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Questions and Answers
Which drug acts by physical means?
Which drug is used in the treatment of Wilson’s disease by chelating copper?
Which drug antagonizes heparin?
Which drug increases the permeability of bacterial plasma membrane?
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Which drug inhibits protein synthesis in bacteria by binding to 50 S ribosomal subunit?
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Study Notes
Drug Actions and Mechanisms
- Physical Action Drug: Activated charcoal acts by adsorbing toxins and chemicals in the gastrointestinal tract, thus preventing their absorption into the body.
Specific Drug Treatments
- Wilson's Disease Treatment: Penicillamine is utilized for treating Wilson's disease by chelating excess copper, facilitating its excretion through urine.
Anticoagulant Antagonists
- Heparin Antagonist: Protamine sulfate is the drug that acts as an antagonist to heparin, reversing its anticoagulant effects effectively.
Bacterial Membrane Permeability
- Membrane Permeability Increasing Drug: Polymyxin B operates by increasing the permeability of the bacterial plasma membrane, leading to cell death and is primarily effective against Gram-negative bacteria.
Antibiotic Protein Synthesis Inhibitors
- Protein Synthesis Inhibition: Erythromycin inhibits bacterial protein synthesis by binding to the 50 S subunit of the ribosome, disrupting peptide chain elongation.
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Description
Learn about pharmacodynamics and its significance in understanding the biochemical and pharmacological effects of drugs and their mechanisms of action. Explore non-receptor mediated drug actions, such as chemical and physical means, and their impact on the body.
