Pharmaceuticals: Disadvantages of Parenteral Administration

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10 Questions

What is the purpose of the glycerol in the O/W lipid emulsions?

To ensure isotonicity

What range of particle size is used in O/W lipid emulsions to simulate chylomicra?

0.1-0.5 µm

What is the pH range for the O/W lipid emulsions mentioned?

5.5-8

Which of the following methods is NOT used to prepare dry powders that are reconstituted before injection?

Sonication

Why are some drugs prepared as dry powders for parenteral dosage forms?

Because they are unstable in liquid formulations

What percentage range of lipid is contained in O/W lipid emulsions for providing essential fatty acids in TPN?

10-20%

After reconstitution, a dry powder may become either a:

solution or a suspension

During freeze drying, how is the product initially filled into vials?

As a liquid

What is the main use of O/W lipid emulsions in TPN?

To provide essential fatty acids

Which email address can be used to contact for more information?

This quiz covers the drawbacks of using parenteral administration, including pain, infection, and psychological distress.

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