Pharmaceuticals: Disadvantages of Parenteral Administration
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Questions and Answers

What is the purpose of the glycerol in the O/W lipid emulsions?

  • To ensure isotonicity (correct)
  • To adjust pH
  • To provide essential fatty acids
  • To act as a thickening agent

What range of particle size is used in O/W lipid emulsions to simulate chylomicra?

  • 0.1-0.5 µm (correct)
  • 1-2 µm
  • 10-20 µm
  • 0.5-1 µm

What is the pH range for the O/W lipid emulsions mentioned?

  • 4-7
  • 6-9
  • 5.5-8 (correct)
  • 3.5-6

Which of the following methods is NOT used to prepare dry powders that are reconstituted before injection?

<p>Sonication (A)</p> Signup and view all the answers

Why are some drugs prepared as dry powders for parenteral dosage forms?

<p>Because they are unstable in liquid formulations (A)</p> Signup and view all the answers

What percentage range of lipid is contained in O/W lipid emulsions for providing essential fatty acids in TPN?

<p>10-20% (B)</p> Signup and view all the answers

After reconstitution, a dry powder may become either a:

<p>solution or a suspension (A)</p> Signup and view all the answers

During freeze drying, how is the product initially filled into vials?

<p>As a liquid (B)</p> Signup and view all the answers

What is the main use of O/W lipid emulsions in TPN?

<p>To provide essential fatty acids (A)</p> Signup and view all the answers

Which email address can be used to contact for more information?

<p><a href="mailto:[email protected]">[email protected]</a> (C)</p> Signup and view all the answers

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