5 Questions
What is the dispersion medium for coarse suspensions?
Oily liquid
What characterizes deflocculated suspensions?
Clear supernatant
What is the dispersed phase in coarse suspensions?
Insoluble solid
What type of suspensions are formulated for non-stable drugs?
Reconstituted suspensions
What is the role of pharmaceutical excipients in suspensions?
To control the formulation and performance
Study Notes
Suspension Characteristics
- The dispersion medium for coarse suspensions is typically a liquid, which can be water or a non-aqueous solvent.
- Deflocculated suspensions are characterized by individual particles or very small aggregates, which are dispersed throughout the dispersion medium.
Coarse Suspensions
- The dispersed phase in coarse suspensions is composed of large, visible particles that settle out of the dispersion medium over time.
Formulation for Unstable Drugs
- Suspensions are formulated for non-stable drugs to improve their stability and solubility.
Role of Pharmaceutical Excipients
- Pharmaceutical excipients play a crucial role in suspensions as they help to stabilize the dispersed phase, prevent settling, and improve the overall physical and chemical stability of the suspension.
Test your understanding of pharmaceutical suspensions formulation principles, including physicochemical principles, comparison between Flocculated and Deflocculated suspensions, the role of pharmaceutical excipients, and independent formulation of suspensions.
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