10 Questions
What is the size range of the dispersed phase in pharmaceutical suspensions and emulsions?
0.1mm to 5 microns
What is the purpose of a suspending agent in pharmaceutical suspensions?
To maintain uniform dispersion of solid particles in the vehicle
What is a disadvantage of pharmaceutical suspensions?
Physical stability issues leading to sedimentation
What is the external phase in pharmaceutical suspensions generally composed of?
Aqueous medium
Which of the following is a disadvantage of liquid dosage forms?
Shorter shelf life compared to other dosage forms
What is an example of a parenteral suspension?
Procaine penicillin G Zinc Suspension
Which of the following is an example of an oily vehicle for liquid dosage forms?
Vegetable oils
Which of the following is an example of a coloring agent for liquid dosage forms?
Tincture lemon
What is the purpose of a wetting agent in liquid dosage forms?
To improve dispersion of the drug in the vehicle
What is the advantage of liquid dosage forms for pediatric and geriatric use?
They are easier to swallow
Study Notes
Pharmaceutical Suspensions and Emulsions
- The size range of the dispersed phase in pharmaceutical suspensions and emulsions is typically between 0.1-100 μm.
- Suspending agents in pharmaceutical suspensions serve to prevent sedimentation and maintain the uniform distribution of the dispersed phase.
- A disadvantage of pharmaceutical suspensions is that the particles may settle over time, leading to inconsistent dosing.
Composition of Pharmaceutical Suspensions
- The external phase in pharmaceutical suspensions is generally composed of water or a aqueous solution.
Disadvantages of Liquid Dosage Forms
- A disadvantage of liquid dosage forms is that they can be susceptible to microbiological contamination.
Examples of Pharmaceutical Suspensions
- An example of a parenteral suspension is insulin.
Oily Vehicles for Liquid Dosage Forms
- Mineral oil is an example of an oily vehicle for liquid dosage forms.
Coloring Agents for Liquid Dosage Forms
- Certified food dyes are an example of a coloring agent for liquid dosage forms.
Wetting Agents in Liquid Dosage Forms
- The purpose of a wetting agent in liquid dosage forms is to reduce the interfacial tension between the active pharmaceutical ingredient and the vehicle, allowing for better dispersion and dissolution.
Advantages of Liquid Dosage Forms
- One advantage of liquid dosage forms is that they are often easier to administer to pediatric and geriatric patients, who may have difficulty swallowing solid dosage forms.
Test your knowledge of pharmaceutical suspensions and emulsions with this quiz. Learn about the characteristics, types, and definitions of these biphasic liquid dosage forms. Explore the differences between suspensions and emulsions and enhance your understanding of their applications in pharmaceutical formulations.
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