Pharmaceutical Organic Chemistry I Exam
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Questions and Answers

What is the primary difference between SN 1 and SN 2 reactions?

  • Order of reactivity of reaction
  • Kinetics of reaction
  • Stereochemistry of reaction
  • Mechanism of reaction (correct)
  • What is the major factor affecting the acidity of carboxylic acids?

  • Substituent effect (correct)
  • Electronegativity of the atom
  • Conjugation of the acid
  • Molecular weight of the acid
  • Which type of reaction is involved in the formation of alkylhalides from alkanes?

  • Electrophilic addition
  • Electrophilic substitution
  • Free radical substitution (correct)
  • Nucleophilic substitution
  • What is the primary use of paraffins?

    <p>As a lubricant</p> Signup and view all the answers

    Which type of reaction is involved in the formation of conjugated dienes?

    <p>Allylic rearrangement</p> Signup and view all the answers

    What is the primary characteristic of E 1 reactions?

    <p>Unimolecular mechanism</p> Signup and view all the answers

    What is the primary test used to identify amines?

    <p>Hinsberg test</p> Signup and view all the answers

    What is the primary use of chloroform?

    <p>As an anesthetic</p> Signup and view all the answers

    Study Notes

    Pharmaceutical Organic Chemistry I

    SN1 and SN2 Reactions

    • SN1 and SN2 reactions of alkyl halides: write reactions and explain kinetics, order of reactivity, and stereochemistry
    • Factors affecting SN1 and SN2 reactions

    Named Reactions

    • Crossed aldol condensation: write reaction with mechanism
    • Benzoin condensation: write reaction with mechanism
    • Crossed cannizaro reaction: write reaction with mechanism
    • Aldol condensation: write reaction with mechanism

    E1 and E2 Reactions

    • E1 vs E2 reactions: explain differences and factors affecting each
    • Acidity of carboxylic acids: explain and describe effects of substituents on acidity

    Amines

    • Basicity of amines: explain
    • Qualitative tests for amines: describe

    Alkyl Halides and Alkenes

    • Elimination reactions of alkyl halides: explain and provide examples
    • Electrophilic addition reactions of alkenes: explain and provide examples
    • Ozonolysis reaction: write reaction

    Organic Compounds

    • Structure and IUPAC name of organic compounds: explain for each class

    Halogenation and Radical Addition

    • Halogenation of alkanes: explain and describe uses of paraffins
    • Free radical addition reactions of alkenes: explain and describe anti-Markovnikov's orientation

    Allylic Rearrangement and Conjugated Dienes

    • Allylic rearrangement: explain
    • Stability of conjugated dienes: explain

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    Description

    This quiz is for the second semester of B.Pharm degree examination, covering topics in pharmaceutical organic chemistry. It consists of essay questions to test knowledge and understanding of the subject.

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