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Questions and Answers
What is the mechanism of action of Mupirocin?
What is the mechanism of action of Mupirocin?
- Activates the 30S ribosomal subunit
- Inhibits DNA replication
- Binds with and inhibits isoleucine synthetase enzyme (correct)
- Inhibits RNA synthesis
Which bacteria are targeted by Mupirocin?
Which bacteria are targeted by Mupirocin?
- Gram-negative bacteria only
- Gram-positive bacteria only (correct)
- Anaerobic bacteria
- Gram-positive and Gram-negative bacteria
What is the basis for the inhibition of protein synthesis by Mupirocin?
What is the basis for the inhibition of protein synthesis by Mupirocin?
- Structural similarity between mupirocin molecule and DNA
- Structural similarity between mupirocin molecule and RNA
- Structural similarity between mupirocin molecule and isoleucine (correct)
- Structural similarity between mupirocin molecule and the 30S ribosomal subunit
Which gene mutation can lead to resistance to Mupirocin?
Which gene mutation can lead to resistance to Mupirocin?
How are Tetracyclines and Glycylcyclines composed?
How are Tetracyclines and Glycylcyclines composed?
What is the spectrum of application for Tetracyclines and Glycylcyclines?
What is the spectrum of application for Tetracyclines and Glycylcyclines?
Which mechanism of resistance to aminoglycosides involves the production of inactivation enzymes?
Which mechanism of resistance to aminoglycosides involves the production of inactivation enzymes?
Which drug binds to the 50S ribosomal subunit to prevent the formation of the initiation complex?
Which drug binds to the 50S ribosomal subunit to prevent the formation of the initiation complex?
What is the main route of administration for Oxazolidinones like Linezolid?
What is the main route of administration for Oxazolidinones like Linezolid?
Which of the following is NOT a drug affecting the 50S ribosomal subunit?
Which of the following is NOT a drug affecting the 50S ribosomal subunit?
What is the main reason for using the combination of drugs discussed in the text?
What is the main reason for using the combination of drugs discussed in the text?
Which of the following is a key advantage of co-trimoxazole highlighted in the text?
Which of the following is a key advantage of co-trimoxazole highlighted in the text?
What is the mechanism of action (MOA) of Rifamycins like rifampicin?
What is the mechanism of action (MOA) of Rifamycins like rifampicin?
Which type of bacteria is rifampicin particularly active against?
Which type of bacteria is rifampicin particularly active against?
What makes rifampicin useful in the treatment of tuberculous meningitis?
What makes rifampicin useful in the treatment of tuberculous meningitis?
Which statement best describes the bactericidal effect of rifampicin?
Which statement best describes the bactericidal effect of rifampicin?
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