Pharmaceutical Market Landscape Quiz
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Questions and Answers

What is the main difference in the duration of action between Salmeterol and Formoterol?

  • Salmeterol has a duration of action of 12 hours, while Formoterol has a duration of action of 7 hours (correct)
  • Salmeterol and Formoterol both have a duration of action of 12 hours
  • Salmeterol and Formoterol both have a duration of action of 7 hours
  • Salmeterol has a duration of action of 7 hours, while Formoterol has a duration of action of 12 hours

    • Which medication has a higher protein binding, leading to lower systemic side effects?

  • Formoterol
  • Fluticasone propionate
  • Salmeterol (correct)
  • Budesonide

    • Which combination of medications is reported to achieve the highest percentage of total control in asthma according to the concept study?

  • Budesonide and Formoterol
  • Salmeterol and Fluticasone propionate
  • Seroflo (Salmeterol and Fluticasone propionate) (correct)
  • Budesonide and Beclomethasone

    • What is the maximum daily dose of Salmeterol?

    <p>160mcg</p> Signup and view all the answers

    What is the main problem with the duration of action of Formoterol?

    <p>Too short, requiring more than twice daily use</p> Signup and view all the answers

    Which medication is classified as a fast-acting bronchodilator?

    <p>Formoterol</p> Signup and view all the answers

    Which medication is reported to achieve the highest percentage of total control in asthma according to the concept study?

    <p>Fluticasone propionate</p> Signup and view all the answers

    Which of the following best describes the mechanism of action of Salmeterol?

    <p>Activation of intracellular adenyl cyclase leading to increased cAMP levels and bronchial smooth muscle relaxation</p> Signup and view all the answers

    Which of the following is an advantage of Fluticasone Propionate over oral corticosteroids?

    <p>Low systemic side effects</p> Signup and view all the answers

    What is the primary effect of Salmeterol on cytokine secretion?

    <p>Reduction of cytokine secretion</p> Signup and view all the answers

    How does Fluticasone Propionate primarily contribute to the improvement in asthma and allergic responses?

    <p>Inhibition of inflammatory cells and secretion of histamines, cytokines, and leukotrienes</p> Signup and view all the answers

    What is the onset of action for Salmeterol in Seroflo?

    <p>30 minutes</p> Signup and view all the answers

    For which patient populations is Seroflo indicated?

    <p>Adults and adolescents</p> Signup and view all the answers

    What is the primary mechanism of action for Fluticasone propionate in Seroflo?

    <p>Inhibiting inflammatory cells</p> Signup and view all the answers

    In what forms are Seroflo and Symbicort available?

    <p>DPI and MDI</p> Signup and view all the answers

    What percentage of the total market does the private sector represent?

    <p>78%</p> Signup and view all the answers

    Which product leads the ICS/LABA combination market with 30% YOY 2022 growth in the private sector?

    <p>Budesonide/Formoterol</p> Signup and view all the answers

    What is the total market size for the Combination ICS/LABA operating at 24% growth YOY 2022?

    <p>$2,819,055$ units</p> Signup and view all the answers

    What is the main driver of growth in the total market for the Asthma ICS Combination market?

    <p>Private market</p> Signup and view all the answers

    Which medication is gaining market share in both private and public sectors?

    <p>Bufomix</p> Signup and view all the answers

    Which product is experiencing significant growth and gaining market share mainly driven by the public sector?

    <p>Airtec</p> Signup and view all the answers

    Which medication is losing market share primarily in the public sector to Airtec?

    <p>Seretide</p> Signup and view all the answers

    Which competitor is gaining market share from the SFP market in the private sector?

    <p>Combiwave</p> Signup and view all the answers

    What is the maximum daily dose of Salmeterol?

    <p>120mcg</p> Signup and view all the answers

    What is the main problem with the duration of action of Formoterol?

    <p>Short duration of action</p> Signup and view all the answers

    Which medication is classified as a fast-acting bronchodilator?

    <p>Formoterol</p> Signup and view all the answers

    What is the primary difference in protein binding between Salmeterol and Formoterol?

    <p>Salmeterol has higher protein binding</p> Signup and view all the answers

    Which medication is reported to achieve the highest percentage of total control in asthma according to the concept study?

    <p>Fluticasone propionate</p> Signup and view all the answers

    For which patient populations is Seroflo indicated?

    <p>Adult patients with asthma using ICS only</p> Signup and view all the answers

    What is the percentage of the total market represented by the public sector?

    <p>22%</p> Signup and view all the answers

    Which molecule leads the market with 30% YOY 2022 growth in the private sector for the ICS/LABA combination?

    <p>Budesonide/Formoterol</p> Signup and view all the answers

    What is the main driver of growth for the Asthma ICS Combination market?

    <p>Private market</p> Signup and view all the answers

    What is the growth rate for the MDI dosage form in the Asthma ICS Combination market in the private sector?

    <p>28%</p> Signup and view all the answers

    Which product is the leading product in the Asthma Combination market?

    <p>Symbicort 160</p> Signup and view all the answers

    What is the total market size for the Combination ICS/LABA operating at 24% growth YOY 2022?

    <p>2,819,055 units</p> Signup and view all the answers

    What is the primary difference in the onset of action between Seroflo and Symbicort?

    <p>Seroflo has an onset of action of 30 minutes, while Symbicort has an onset of action of 15 minutes</p> Signup and view all the answers

    In what patient populations is Seroflo indicated?

    <p>Asthma and COPD in adults and adolescents</p> Signup and view all the answers

    What is the primary mechanism of action of Fluticasone propionate in Seroflo?

    <p>It has a glucocorticoid anti-inflammatory action within the lungs</p> Signup and view all the answers

    Which medication may be used with a spacer device for patients who find it difficult to synchronize aerosol actuation with breath inspiration?

    <p>Seroflo</p> Signup and view all the answers

    What is the duration of action for both Seroflo and Symbicort?

    <p>12 hours</p> Signup and view all the answers

    What are the primary disadvantages of both Seroflo and Symbicort?

    <p>Oral infection, tremors, palpitation, and difficulty in usage</p> Signup and view all the answers

    Which medication is losing market share by 14% in the public sector primarily to Airtec?

    <p>Seretide</p> Signup and view all the answers

    Which product is gaining market share from the SFP (Seretide) market in the private sector?

    <p>BUD/FOR</p> Signup and view all the answers

    What is the primary driver of Airtec's significant growth in the total asthma market?

    <p>Public sector demand</p> Signup and view all the answers

    Which medication represents 17% of the total asthma market and is experiencing a 34% increase, mainly driven by the public market?

    <p>Airtec MDI</p> Signup and view all the answers

    Which medication is gaining market share from Seretide MDI in the public sector and starting to gain market share from Seretide in the private sector?

    <p>Airtec-SF</p> Signup and view all the answers

    Which medication is reported to achieve the highest percentage of total control in asthma according to the concept study?

    <p>Symbicort</p> Signup and view all the answers

    Which of the following accurately describes the mechanism of action of Salmeterol?

    <p>Activation of intracellular adenyl cyclase, leading to increased cAMP levels and bronchial smooth muscle relaxation</p> Signup and view all the answers

    Which of the following is a primary effect of Fluticasone Propionate in the context of asthma and allergic responses?

    <p>Inhibition of inflammatory cell activity and reduction of histamine, cytokine, and leukotriene secretion</p> Signup and view all the answers

    What is the main advantage of Fluticasone Propionate over oral corticosteroids?

    <p>Low systemic side effects</p> Signup and view all the answers

    How does Salmeterol primarily contribute to the improvement in COPD?

    <p>Reduction of cytokine secretion and improved mucociliary clearance</p> Signup and view all the answers

    Which of the following accurately describes the mechanism of action of Salmeterol compared to salbutamol (albuterol)?

    <p>At least 50 times more selective for β2‐adrenoceptors</p> Signup and view all the answers

    What is the primary action of increased cAMP levels due to the binding of Salmeterol to the β2‐adrenoceptor?

    <p>Bronchial smooth muscle relaxation</p> Signup and view all the answers

    Study Notes

    Pharmaceutical Market Analysis 2022

    • The pharmaceutical market for bronchial asthma and chronic obstructive pulmonary disease (COPD) is growing at a rate of 30% year over year in both private (38% YOY) and public (21% YOY) sectors.
    • Symbicort (AstraZeneca) is losing market share in both private (4% YOY) and public (11% YOY) sectors, while Bufomix (Hikma) is gaining market share, particularly in the private sector.
    • Airtec is experiencing significant growth in both private and public sectors, gaining a 34% market share increase, mainly driven by the public sector.
    • Seretide is losing market share by 14%, primarily in the public sector, to Airtec.
    • The market share of SFP (seretide) is growing, while all other similar products are losing market share except for Seretide 125 (MDI) in the private sector and Seretide 250 (DPI) in the public sector.
    • Airtec-SF (Combiwave) is gaining market share from Seretide (MDI) in the public sector and BUD/FOR is gaining market share from the SFP market in the private sector.
    • Airtec MDI is gaining market share, representing 17% of the total asthma market and experiencing a 34% increase, mainly driven by the public market.
    • Airtec is gaining market share from Seretide MDI in the public sector and starting to gain market share from Seretide in the private sector.
    • The competitor landscape includes Symbicort, Seretide, Relvar Ellipta, Bufomix, Airtec-SF, and Flutiform, with various manufacturers and doses.
    • The analysis includes a comparison of molecules in Symbicort, Seretide, Bufomix, Combiwave, and Formoterol, focusing on their uses and potential side effects.
    • Detailed information is provided regarding the doses, manufacturers, and prices of different products such as Symbicort, Seretide, Bufomix, Airtec-SF, and Flutiform.
    • The text provides a comprehensive understanding of the pharmaceutical market trends, including market growth, product performance, and competitor landscape in the bronchial asthma and COPD sector.

    Pharmaceutical Market Analysis 2022

    • The pharmaceutical market for bronchial asthma and chronic obstructive pulmonary disease (COPD) is growing at a rate of 30% year over year in both private (38% YOY) and public (21% YOY) sectors.
    • Symbicort (AstraZeneca) is losing market share in both private (4% YOY) and public (11% YOY) sectors, while Bufomix (Hikma) is gaining market share, particularly in the private sector.
    • Airtec is experiencing significant growth in both private and public sectors, gaining a 34% market share increase, mainly driven by the public sector.
    • Seretide is losing market share by 14%, primarily in the public sector, to Airtec.
    • The market share of SFP (seretide) is growing, while all other similar products are losing market share except for Seretide 125 (MDI) in the private sector and Seretide 250 (DPI) in the public sector.
    • Airtec-SF (Combiwave) is gaining market share from Seretide (MDI) in the public sector and BUD/FOR is gaining market share from the SFP market in the private sector.
    • Airtec MDI is gaining market share, representing 17% of the total asthma market and experiencing a 34% increase, mainly driven by the public market.
    • Airtec is gaining market share from Seretide MDI in the public sector and starting to gain market share from Seretide in the private sector.
    • The competitor landscape includes Symbicort, Seretide, Relvar Ellipta, Bufomix, Airtec-SF, and Flutiform, with various manufacturers and doses.
    • The analysis includes a comparison of molecules in Symbicort, Seretide, Bufomix, Combiwave, and Formoterol, focusing on their uses and potential side effects.
    • Detailed information is provided regarding the doses, manufacturers, and prices of different products such as Symbicort, Seretide, Bufomix, Airtec-SF, and Flutiform.
    • The text provides a comprehensive understanding of the pharmaceutical market trends, including market growth, product performance, and competitor landscape in the bronchial asthma and COPD sector.

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