Pharmaceutical Industry Challenges
30 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the estimated annual loss of exclusivity for the pharmaceutical industry from 2008 to 2011?

  • $11 Bn (correct)
  • $5 Bn
  • $10 Bn
  • $15 Bn

What is the perception problem faced by Brand Pharma?

  • High research costs
  • The Big Evil Pharma (correct)
  • Increasing competition from generics
  • Inadequate safety measures

Which industry has the highest R&D percentage of sales?

  • Drugs & Medicine
  • Electrical & Electronics
  • Computer Software & Services
  • Research-based Pharmaceuticals (correct)

What is the pressure faced by the pharmaceutical industry due to healthcare reforms?

<p>Further payor pressure (B)</p> Signup and view all the answers

What is the challenge faced by the pharmaceutical industry due to patent expiries?

<p>Loss of exclusivity (B)</p> Signup and view all the answers

What percentage of sales do Research-based Pharmaceuticals spend on R&D?

<p>17.5% (C)</p> Signup and view all the answers

What was the most significant discovery of the 20th century in the context of drug development?

<p>The Randomised, Double Blind, Placebo Controlled Clinical Trial (C)</p> Signup and view all the answers

What is the cumulative success rate of the Pre-Clinical Phase in the 2000-2003 period?

<p>68.23% (A)</p> Signup and view all the answers

What is the average development timeframe in years in the 2010s?

<p>4.3 (B)</p> Signup and view all the answers

What was the outcome of the drug amendments in the USA in the 1960s?

<p>The establishment of the FDA (C)</p> Signup and view all the answers

What is the main challenge for Pharma innovation according to the Bain Consulting Drug Development Attrition Model?

<p>All of the above (D)</p> Signup and view all the answers

What was the outcome of the enactment of the SAPHRA act in 2017?

<p>The modernisation of clinical trials in South Africa (C)</p> Signup and view all the answers

How many total developments from first-time in man (FIM) to FDA registration has South Africa achieved?

<p>3 (C)</p> Signup and view all the answers

What is the primary reason for the decline in Pharma innovation?

<p>Increasing payor pressures and shorter exclusivity periods (A)</p> Signup and view all the answers

What is the last anti-TB drug registered in South Africa?

<p>Rifapentine (C)</p> Signup and view all the answers

What was the outcome of Pfizer's $900 million investment in testing its HDL increasing drug, torcetrapib?

<p>The drug failed in Phase III (D)</p> Signup and view all the answers

What is the name of the device that is currently being developed in South Africa?

<p>BURL- device (D)</p> Signup and view all the answers

What is one of the FDA's six priority public health challenges in 2004?

<p>Developing antibiotics and countermeasures to combat emerging infections and bioterrorism (A)</p> Signup and view all the answers

What is one of the benefits of using innovative study designs in clinical trials?

<p>Optimal designs of trial protocols (A)</p> Signup and view all the answers

What is a key aspect of the creative process delivery in clinical trials?

<p>Electronic data capturing (D)</p> Signup and view all the answers

What is one of the areas where South Africa has a competitive edge?

<p>Primate research (B)</p> Signup and view all the answers

What is required for research clinicians?

<p>All of the above (D)</p> Signup and view all the answers

What is a key benefit of a drug development-friendly regulatory authority?

<p>28-day CTA-exemption (C)</p> Signup and view all the answers

What can individuals do to support clinical research at the UP Medical school?

<p>Create a research culture (A)</p> Signup and view all the answers

What was the outcome of the 15,000-patient study on torcetrapib in December 2006?

<p>It revealed that the chemical increased death rates (D)</p> Signup and view all the answers

What is the main goal of personalised medicine?

<p>To increase the efficacy of drugs while reducing adverse events (C)</p> Signup and view all the answers

According to the source, how much can the cost of drug development be reduced with the help of pharmacogenomics?

<p>$1.3 billion to $200 million (C)</p> Signup and view all the answers

What is the potential benefit of using biomarkers in drug development?

<p>Early elimination of unviable/unsafe candidates (B)</p> Signup and view all the answers

What is the main advantage of predictive bio-simulation in drug development?

<p>It can replace distant clinical endpoints with more proximal surrogate endpoints (B)</p> Signup and view all the answers

What is the estimated time-to-market for a new drug with the help of pharmacogenomics?

<p>2-4 years (D)</p> Signup and view all the answers

More Like This

Use Quizgecko on...
Browser
Browser