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Questions and Answers
What is the purpose of controlled flocculation in pharmaceutical dosage forms?
What is the purpose of controlled flocculation in pharmaceutical dosage forms?
- To increase the zeta potential of particles
- To induce the formation of a cake
- To prevent the formation of compact sediment (correct)
- To disperse the particles evenly
How is controlled flocculation usually achieved?
How is controlled flocculation usually achieved?
- Addition of surfactants only
- Use of extreme heat and pressure
- Combination of particle size control, use of electrolytes, and addition of polymers (correct)
- Mechanical agitation only
What is the role of electrolytes in converting a suspension from a deflocculated to a partially flocculated state?
What is the role of electrolytes in converting a suspension from a deflocculated to a partially flocculated state?
- Alter the zeta potential and reduce the electric barrier between particles (correct)
- Increase the repulsion force between particles
- Cause further deflocculation
- Stabilize the suspension
What do polymers termed as 'polyelectrolytes' do in controlled flocculation?
What do polymers termed as 'polyelectrolytes' do in controlled flocculation?
How do electrolytes act as flocculating agents?
How do electrolytes act as flocculating agents?
What are the most widely used electrolytes for flocculation?
What are the most widely used electrolytes for flocculation?
What effect does a decrease in zeta potential have on suspended particles?
What effect does a decrease in zeta potential have on suspended particles?
Which type of surfactants can cause flocculation by neutralizing the charge?
Which type of surfactants can cause flocculation by neutralizing the charge?
How do optimum concentrations of surfactants reduce the surface tension between liquid medium and solid particles?
How do optimum concentrations of surfactants reduce the surface tension between liquid medium and solid particles?
What effect do non-ionic surfactants have on the charge density of a particle?
What effect do non-ionic surfactants have on the charge density of a particle?
How do polymeric flocculating agents promote flocculation?
How do polymeric flocculating agents promote flocculation?
What is the purpose of structured entrapping vehicles in relation to flocculated particles?
What is the purpose of structured entrapping vehicles in relation to flocculated particles?
Which type of polymers are examples of structured entrapping vehicles?
Which type of polymers are examples of structured entrapping vehicles?
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What are structured vehicles used to increase in suspensions?
What are structured vehicles used to increase in suspensions?
