Podcast
Questions and Answers
Which factor is NOT considered when designing chemical isosteres?
Which factor is NOT considered when designing chemical isosteres?
- Hydrogen bonding
- Molecular weight
- Charge
- Size (correct)
What purpose can the isosteric replacement of functional groups serve?
What purpose can the isosteric replacement of functional groups serve?
- Reduce duration of action
- Enhance side effects
- Decrease specificity
- Increase potency (correct)
Which compound is mentioned as an example of bioisosteres in the text?
Which compound is mentioned as an example of bioisosteres in the text?
- Procainamide (correct)
- Alloxanthine
- Procaine
- Xanthine
What effect does isosteric replacement have on the duration of action of a compound?
What effect does isosteric replacement have on the duration of action of a compound?
Which compound acts as an inhibitor of xanthine oxidase and is an isostere of xanthine?
Which compound acts as an inhibitor of xanthine oxidase and is an isostere of xanthine?
How does alloxanthine act in relation to xanthine according to the text?
How does alloxanthine act in relation to xanthine according to the text?
What is the main focus of Pharmaceutical Chemistry?
What is the main focus of Pharmaceutical Chemistry?
What does the term 'Structure-Activity Relationship' refer to in Pharmaceutical Chemistry?
What does the term 'Structure-Activity Relationship' refer to in Pharmaceutical Chemistry?
Which functional group in drugs plays a role in muscle relaxant activity?
Which functional group in drugs plays a role in muscle relaxant activity?
What is the key aspect to consider in pharmaceutical applications related to stereochemistry?
What is the key aspect to consider in pharmaceutical applications related to stereochemistry?
Which concept focuses on the relationship between molecular structure and biological activity of drugs?
Which concept focuses on the relationship between molecular structure and biological activity of drugs?
In Pharmaceutical Chemistry, what does the term 'Epimers' refer to?
In Pharmaceutical Chemistry, what does the term 'Epimers' refer to?
What does the Partition Coefficient (P) in Pharmaceutical Chemistry represent?
What does the Partition Coefficient (P) in Pharmaceutical Chemistry represent?
What is the main characteristic of Inorganic salts in pharmaceutical applications?
What is the main characteristic of Inorganic salts in pharmaceutical applications?
Which rule is also known as Pfizer’s Rule of Five and is used to evaluate drug-likeness?
Which rule is also known as Pfizer’s Rule of Five and is used to evaluate drug-likeness?
In what form are Organic salts made in pharmaceutical chemistry?
In what form are Organic salts made in pharmaceutical chemistry?
What is the purpose of using Inorganic salts in pharmaceutical formulations?
What is the purpose of using Inorganic salts in pharmaceutical formulations?
Which class of salts has increased lipid solubility and is generally used for depot injections?
Which class of salts has increased lipid solubility and is generally used for depot injections?
