Peroxisomes
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Questions and Answers

What is the approximate diameter of a peroxisome?

  • 0.5 µm (correct)
  • 1.5 µm
  • 0.05 µm
  • 5 µm
  • Where are integral membrane proteins of peroxisomes synthesized?

  • Mitochondria
  • Nucleus
  • Golgi apparatus
  • Endoplasmic reticulum (correct)
  • How do peroxisomes replicate?

  • By meiosis
  • By fusion
  • By budding
  • By fission (correct)
  • Where are peroxisomal precursor vesicles formed?

    <p>Budding part of endoplasmic reticulum</p> Signup and view all the answers

    Where are most of the peroxisome matrix and membrane proteins synthesized?

    <p>Cytoplasm</p> Signup and view all the answers

    How many known peroxisomal proteins, called peroxins, participate in the process of peroxisome assembly?

    <p>At least 50</p> Signup and view all the answers

    What is the approximate half-life of peroxisomes?

    <p>5 days</p> Signup and view all the answers

    How are peroxisomes degraded?

    <p>By themselves or when fusing with lysosomes</p> Signup and view all the answers

    What is the function of peroxisomes?

    <p>Contain more than 60 different enzymes</p> Signup and view all the answers

    What is the primary function of peroxisomes?

    <p>Detoxification</p> Signup and view all the answers

    Which enzyme is responsible for the conversion of excessive hydrogen peroxide to water?

    <p>Catalase</p> Signup and view all the answers

    What process occurs in peroxisomes to convert fatty acids to acetyl CoA?

    <p>8-oxidation</p> Signup and view all the answers

    What lipid molecules are synthesized in peroxisomes?

    <p>Cholesterol and dolichol</p> Signup and view all the answers

    Where does the synthesis of bile acids primarily occur?

    <p>Peroxisomes</p> Signup and view all the answers

    What is the product of the oxidation of ethanol in peroxisomes?

    <p>Acetaldehyde</p> Signup and view all the answers

    Which reactive oxygen species are detoxified in peroxisomes?

    <p>Hydrogen peroxide and superoxide anions</p> Signup and view all the answers

    What is the primary function of catalases in peroxisomes?

    <p>To convert hydrogen peroxide to water</p> Signup and view all the answers

    Which of the following is NOT a process associated with peroxisomes?

    <p>Breakdown of amino acids</p> Signup and view all the answers

    What is the primary role of peroxisomes in the synthesis of plasmalogens?

    <p>Important membrane components synthesis</p> Signup and view all the answers

    Study Notes

    Peroxisome Structure and Formation

    • Diameter of peroxisomes is approximately 0.1 to 1.0 micrometers.
    • Integral membrane proteins of peroxisomes are synthesized in the endoplasmic reticulum.
    • Peroxisomes replicate by a process known as "fission."
    • Peroxisomal precursor vesicles are formed in the endoplasmic reticulum.

    Protein Synthesis and Composition

    • Most peroxisome matrix and membrane proteins are synthesized in the cytosol.
    • There are at least 32 known peroxisomal proteins, called peroxins, that participate in peroxisome assembly.

    Lifespan and Degradation

    • The approximate half-life of peroxisomes is 20 days.
    • Peroxisomes are degraded through a process called autophagy, specifically via selective autophagy.

    Functions and Processes

    • Primary function of peroxisomes includes the breakdown of fatty acids and detoxification of harmful substances.
    • Peroxisomes convert fatty acids into acetyl CoA through β-oxidation.
    • Synthesis of bile acids primarily occurs in the liver.
    • Lipid molecules synthesized in peroxisomes include plasmalogens and ether lipids.

    Enzymatic Processes

    • Catalase enzyme is responsible for the conversion of excessive hydrogen peroxide (H2O2) into water and oxygen.
    • Reactive oxygen species detoxified in peroxisomes include hydrogen peroxide and superoxide anions.
    • Primary role of catalases in peroxisomes is to eliminate hydrogen peroxide, preventing oxidative damage.

    Additional Information

    • The product of the oxidation of ethanol in peroxisomes is acetaldehyde, which can then be further oxidized.
    • Peroxisomes are also involved in the synthesis of plasmalogens, which play an important role in membrane integrity and function.
    • Processes NOT associated with peroxisomes typically include protein synthesis, which occurs predominantly in ribosomes.

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