Peripheral Neuropathy and Motor Units
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Questions and Answers

Which of the following conditions is characterized by predominant motor fiber involvement?

  • Lead toxicity
  • Guillain-Barre syndrome
  • Carcinoma
  • Charcot-Marie-Tooth disease (correct)

    • Which of the following conditions is associated with sensory neuropathy?

  • Guillain-Barre syndrome
  • Lead toxicity
  • Carcinoma
  • Vitamin B6 toxicity (correct)

    • Which of the following conditions is associated with autonomic nerve involvement?

  • Amyloidosis
  • Guillain-Barre syndrome
  • Diabetes (correct)
  • Vincristine

    • What is the most common type of peripheral neuropathy?

    <p>Axonal</p> Signup and view all the answers

    Which of the following conditions is characterized by demyelination?

    <p>Charcot-Marie-Tooth disease</p> Signup and view all the answers

    Which of the following can cause a hereditary peripheral neuropathy?

    <p>Charcot-Marie-Tooth disease</p> Signup and view all the answers

    Which of the following can cause peripheral neuropathy as a side effect?

    <p>Vincristine</p> Signup and view all the answers

    What are the common features of an inherited neuropathy?

    <p>Orthopedic deformities</p> Signup and view all the answers

    Which of the following can cause demyelinating peripheral neuropathy?

    <p>Cancer drugs</p> Signup and view all the answers

    What is the most likely diagnosis for a 36-year-old woman with numbness, tingling, and weakness in her legs?

    <p>Peripheral neuropathy</p> Signup and view all the answers

    Which of the following is the preferred treatment option for Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) due to its ease of administration?

    <p>IVIG</p> Signup and view all the answers

    How many treatments of plasmapheresis are usually recommended over a period of 8-10 days?

    <p>4-6 treatments</p> Signup and view all the answers

    What percentage of patients with CIDP can walk independently after 6 months?

    <p>65%</p> Signup and view all the answers

    What percentage of patients with CIDP usually recover completely?

    <p>80%</p> Signup and view all the answers

    What percentage of patients with CIDP have a prolonged course with incomplete recovery?

    <p>3-5%</p> Signup and view all the answers

    What percentage of patients with CIDP may require ventilatory support due to respiratory status?

    <p>20-30%</p> Signup and view all the answers

    What percentage of patients with CIDP may experience neuropathic pain?

    <p>70-80%</p> Signup and view all the answers

    What percentage of patients with CIDP may die despite ICU care?

    <p>1-2%</p> Signup and view all the answers

    What percentage of patients with CIDP will develop chronic relapsing disease?

    <p>9-10%</p> Signup and view all the answers

    Which of the following treatments has NO ROLE in the management of CIDP?

    <p>Glucocorticoids</p> Signup and view all the answers

    Which of the following is a characteristic of peripheral neuropathy?

    <p>Diminished sensation in the upper extremities</p> Signup and view all the answers

    What is the distribution of deficits in mononeuropathy?

    <p>Asymmetric</p> Signup and view all the answers

    What is the duration of most polyneuropathies?

    <p>Months to years</p> Signup and view all the answers

    Which fibers are affected in peripheral neuropathy?

    <p>All of the above</p> Signup and view all the answers

    What is the disease pathology in peripheral neuropathy?

    <p>Both axonal and demyelinating</p> Signup and view all the answers

    What is the etiology of peripheral neuropathy?

    <p>All of the above</p> Signup and view all the answers

    What is the most common pattern of peripheral neuropathy?

    <p>Polyneuropathy</p> Signup and view all the answers

    What percentage of individuals over 55 years old have polyneuropathy?

    <p>2.4%</p> Signup and view all the answers

    What is the term used to describe multiple nerves contiguous typically length dependent deficits in polyneuropathy?

    <p>Polyneuropathy</p> Signup and view all the answers

    What is the term used to describe polyneuropathy that affects both motor and sensory fibers?

    <p>Both axonal and demyelinating</p> Signup and view all the answers

    Which of the following treatments is frequently preferred for Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) due to its ease of administration?

    <p>Glucocorticoids</p> Signup and view all the answers

    How many treatments of plasmapheresis are usually recommended over a period of 8-10 days?

    <p>4-6</p> Signup and view all the answers

    What percentage of patients with CIDP have a prolonged course with incomplete recovery?

    <p>5-10%</p> Signup and view all the answers

    What is the percentage of patients with CIDP who may die despite ICU care?

    <p>3%</p> Signup and view all the answers

    What percentage of patients with CIDP can walk independently after 6 months?

    <p>65%</p> Signup and view all the answers

    What is the most likely diagnosis for a 36-year-old woman with numbness, tingling, and weakness in her legs?

    <p>CIDP</p> Signup and view all the answers

    What is the duration of most polyneuropathies?

    <p>Months</p> Signup and view all the answers

    What percentage of patients with CIDP usually recover completely?

    <p>80%</p> Signup and view all the answers

    What is the term used to describe polyneuropathy that affects both motor and sensory fibers?

    <p>Polyneuropathy</p> Signup and view all the answers

    What percentage of patients with CIDP may require ventilatory support due to respiratory status?

    <p>30%</p> Signup and view all the answers

    Which of the following conditions is characterized by immune-mediated demyelination of peripheral nerves?

    <p>Guillain-Barre Syndrome</p> Signup and view all the answers

    Which of the following conditions is associated with sensory neuropathy?

    <p>Amyloid</p> Signup and view all the answers

    What is the most common type of peripheral neuropathy?

    <p>Axonal neuropathy</p> Signup and view all the answers

    What is the term used to describe polyneuropathy that affects both motor and sensory fibers?

    <p>Polyneuropathy</p> Signup and view all the answers

    What is the etiology of peripheral neuropathy in Charcot-Marie-Tooth disease?

    <p>Inherited</p> Signup and view all the answers

    Which of the following conditions is associated with autonomic nerve involvement?

    <p>Diabetes</p> Signup and view all the answers

    Which of the following conditions is characterized by predominant motor fiber involvement?

    <p>Charcot-Marie-Tooth disease</p> Signup and view all the answers

    What is the distribution of deficits in mononeuropathy?

    <p>Asymmetric</p> Signup and view all the answers

    What is the term used to describe multiple nerves contiguous typically length-dependent deficits in polyneuropathy?

    <p>Polyneuropathy</p> Signup and view all the answers

    Which of the following conditions is characterized by axonal neuropathy with preserved deep tendon reflexes?

    <p>Charcot-Marie-Tooth disease</p> Signup and view all the answers

    Which of the following is the term used to describe deficits in multiple nerves that are contiguous and typically length dependent in polyneuropathy?

    <p>Polyneuropathy</p> Signup and view all the answers

    Which of the following is the most common pattern of peripheral neuropathy?

    <p>Polyneuropathy</p> Signup and view all the answers

    What is the duration of most polyneuropathies?

    <p>Months to years</p> Signup and view all the answers

    Which of the following is the term used to describe deficits in a single nerve in mononeuropathy?

    <p>Mononeuropathy</p> Signup and view all the answers

    Which of the following is the term used to describe deficits in multiple nerves in mononeuritis multiplex?

    <p>Mononeuritis multiplex</p> Signup and view all the answers

    Which of the following is the term used to describe deficits in both motor and sensory fibers in polyneuropathy?

    <p>Polyneuropathy</p> Signup and view all the answers

    Which of the following is the term used to describe deficits in sensation in peripheral neuropathy?

    <p>Peripheral neuropathy</p> Signup and view all the answers

    Which of the following is the term used to describe deficits in the upper extremities in peripheral neuropathy?

    <p>UL power 4/5</p> Signup and view all the answers

    Which of the following is the term used to describe deficits in the lower extremities and abdomen in peripheral neuropathy?

    <p>Dorsiflexors and plantar flexors were 3/5 bilaterally</p> Signup and view all the answers

    Which of the following is the term used to describe deficits in gait in peripheral neuropathy?

    <p>Her gait was ataxic</p> Signup and view all the answers

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