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Questions and Answers
What are the primary anatomical components of the peripheral nervous system (PNS)?
What are the primary anatomical components of the peripheral nervous system (PNS)?
Which division of the PNS is responsible for sensory innervation?
Which division of the PNS is responsible for sensory innervation?
What type of sensory stimuli do exteroceptors respond to?
What type of sensory stimuli do exteroceptors respond to?
How many pairs of cranial nerves are present in the human body?
How many pairs of cranial nerves are present in the human body?
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What kind of information do proprioceptors primarily provide?
What kind of information do proprioceptors primarily provide?
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Which of the following is NOT a type of interoceptor?
Which of the following is NOT a type of interoceptor?
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Which type of intervertebral disc abnormality can occur and could lead to spinal stenosis?
Which type of intervertebral disc abnormality can occur and could lead to spinal stenosis?
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Which division of the autonomic nervous system is NOT recognized as part of the PNS?
Which division of the autonomic nervous system is NOT recognized as part of the PNS?
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What type of receptors primarily sense deep touch?
What type of receptors primarily sense deep touch?
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Which receptors are responsible for the sensation of a cold ice cube on your skin?
Which receptors are responsible for the sensation of a cold ice cube on your skin?
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What type of adaptation do nociceptors exhibit?
What type of adaptation do nociceptors exhibit?
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Which of the following medications would reduce the activity of histamine in the body?
Which of the following medications would reduce the activity of histamine in the body?
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What happens to the ion channels in a receptor when it receives a stimulus?
What happens to the ion channels in a receptor when it receives a stimulus?
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Which type of receptors are quick to adapt to stimuli?
Which type of receptors are quick to adapt to stimuli?
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The receptor portion of tactile receptors is a modification of which neuron part?
The receptor portion of tactile receptors is a modification of which neuron part?
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What do opiates chemically resemble in the brain?
What do opiates chemically resemble in the brain?
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What is the purpose of a Snellen chart?
What is the purpose of a Snellen chart?
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What does having 20/40 vision indicate about a person's eyesight?
What does having 20/40 vision indicate about a person's eyesight?
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What does a prescription of -2.5 indicate?
What does a prescription of -2.5 indicate?
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What are the three layers of cells in the retina, in order from innermost to outermost?
What are the three layers of cells in the retina, in order from innermost to outermost?
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Where is the fovea centralis located?
Where is the fovea centralis located?
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What is the main function of ganglion cells in the retina?
What is the main function of ganglion cells in the retina?
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What does the macula of the retina refer to?
What does the macula of the retina refer to?
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Can diopters be directly converted into Snellen chart numbers?
Can diopters be directly converted into Snellen chart numbers?
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What happens to rods when they are bleached?
What happens to rods when they are bleached?
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Which type of cells in the retina have receptors for neurotransmitters released during the bleaching of rods?
Which type of cells in the retina have receptors for neurotransmitters released during the bleaching of rods?
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What happens to retinal when it is exposed to light in rhodopsin?
What happens to retinal when it is exposed to light in rhodopsin?
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Which process helps retinal return to its original conformation after light exposure?
Which process helps retinal return to its original conformation after light exposure?
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What immediate effect does walking from a dark environment into bright light have on rods and cones?
What immediate effect does walking from a dark environment into bright light have on rods and cones?
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What happens to the sensitivity of rods during dark adaptation?
What happens to the sensitivity of rods during dark adaptation?
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What is a likely reason for pirates to wear an eyepatch?
What is a likely reason for pirates to wear an eyepatch?
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How long can it take for rods to recover fully in dark adaptation?
How long can it take for rods to recover fully in dark adaptation?
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What is the primary reason for the symptoms experienced during rapid ascent?
What is the primary reason for the symptoms experienced during rapid ascent?
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Which maneuver can help alleviate pressure-related symptoms in the ear?
Which maneuver can help alleviate pressure-related symptoms in the ear?
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What fluid is contained in the scala media of the cochlea?
What fluid is contained in the scala media of the cochlea?
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What is the main function of the cochlea?
What is the main function of the cochlea?
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Which cells in the organ of Corti are primarily responsible for sending nerve impulses to the brain?
Which cells in the organ of Corti are primarily responsible for sending nerve impulses to the brain?
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What type of fluid do the scala vestibuli and scala tympani contain?
What type of fluid do the scala vestibuli and scala tympani contain?
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Where is the organ of Corti located?
Where is the organ of Corti located?
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Do outer hair cells in the organ of Corti have motile structures?
Do outer hair cells in the organ of Corti have motile structures?
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Study Notes
### Peripheral Nervous System Anatomy
- The PNS is comprised of the cranial and spinal nerves.
- The PNS is functionally organized into two divisions: afferent and efferent.
- The afferent division is responsible for sensory information, including:
- Somatosensory (touch, pressure, temperature, pain)
- Special Sensory (sight, hearing, taste, smell)
- Visceral Sensory (internal organ information)
- The efferent division transmits motor commands and is comprised of:
- Somatic Motor (controls skeletal muscle)
- Autonomic Motor (controls smooth muscle, cardiac muscle, glands, and adipose tissue)
- The autonomic motor system further subdivides into the sympathetic, parasympathetic, and enteric nervous systems.
Sensory Receptors
- Exteroceptors are sensory receptors that receive external stimuli from both special and somatic senses.
- Proprioceptors provide the CNS with information about joint angle, muscle length, and muscle tension, ultimately giving information about limb position.
- Interoceptors receive stimuli from internal organs, providing information about visceral sensations.
Cranial and Spinal Nerves
- There are 12 pairs of cranial nerves, some of which are mixed (containing both sensory and motor fibers).
- There are 31 pairs of spinal nerves.
Spinal Stenosis
- Intervertebral disc abnormalities can lead to spinal stenosis:
- Deterioration: Weakening and breakdown of the disc
- Herniation: Protrusion of the disc material, potentially compressing nerves
Touch Receptors
- Pacinian corpuscles detect deep touch.
- Meissner's corpuscles and Merkel cells detect light touch.
Sensory Processing
- Ipsilateral sensory information converges at the brainstem.
- Contralateral sensory information converges at the spinal cord.
Receptor Types
- Thermoreceptors detect temperature.
- Chemoreceptors detect chemical stimuli (e.g., taste).
- Nociceptors detect pain.
- Mechanoreceptors detect pressure and movement.
Receptor Properties
- Nociceptors are tonic, slowly adapting receptors.
- Tactile receptors are phasic, quickly adapting receptors.
- Odorant receptors are phasic.
Sensory Neuron Structure
- Tactile receptors are modifications of a sensory neuron's dendrite.
- Stimulus reception opens ion channels in the receptor, allowing sodium to enter and initiating an action potential at the neuron's initial segment.
Pain Modulation
- NSAIDs (e.g., ibuprofen, aspirin) reduce prostaglandin activity.
- Antihistamines (e.g., Benadryl) reduce histamine activity.
- Capsaicin reduces substance P activity.
- Opiates mimic the effects of the brain's natural opioids (endorphins).
Visual Acuity
- A Snellen chart is used to measure visual acuity.
- 20/20 vision is considered "normal" vision. A person can read the smallest letters on the 20/20 line of a Snellen chart from 20 feet away.
- 20/40 vision indicates myopia (nearsightedness). A person can read the smallest letters on the 20/40 line from 20 feet away, while someone with 20/20 vision can read the same line from 40 feet away.
- 20/20 visual acuity does not mean perfect vision.
### Eyeglass Prescription
- Eyeglass prescriptions are measured in diopters.
- Diopters cannot be directly converted to Snellen chart values.
- A prescription of -2.5 diopters indicates myopia.
### Retinal Structure
- The retina has three layers:
- Ganglion cell layer (innermost)
- Bipolar cell layer (middle)
- Photoreceptor layer (outermost, containing rods and cones)
- The macula is a retinal indentation off-center from the optic disc.
- The fovea centralis is a region within the macula, containing a high concentration of cone photoreceptor cells.
Phototransduction
- Ganglion cells are responsible for firing action potentials in response to light.
- Light stimulates rhodopsin, leading to a conformational change in retinal from cis to trans.
- "Bleaching" of rods occurs when opsin dissociates from retinal in rhodopsin, making rods unresponsive to photons.
- Retinal is converted back to its original conformation via the retinoid cycle, mediated by pigmented epithelial cells of the retina.
### Light and Dark Adaptation
- Light adaptation happens when transitioning from a dark environment to a bright environment, causing temporary dazzling.
- Dark adaptation happens when transitioning from a bright environment to a dark environment, initially resulting in near blindness.
- Over time, rhodopsin regenerates through the retinoid cycle, restoring rod sensitivity.
### Ear Structure
- The inner ear contains a bony labyrinth and a membranous labyrinth.
- Cochlea contains three chambers:
- Scala vestibuli (vestibular duct) - filled with perilymph
- Scala media (cochlear duct) - filled with endolymph
- Scala tympani (tympanic duct) - filled with perilymph
- Membranes associated with these chambers:
- Vestibular membrane
- Tectorial membrane
- Basilar membrane
Organ of Corti
- The organ of Corti is the sensory organ of audition, located within the cochlea.
- It comprises:
- Tectorial membrane
- Outer hair cells
- Basilar membrane
- Inner hair cells
- Support cells
- Inner hair cells fire nerve impulses in response to basilar membrane distortion.
- Outer hair cells amplify basilar membrane vibrations by pushing on the tectorial membrane.
- Stereocilia, found on hair cells, are not motile structures.
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Description
Test your knowledge on the anatomy and functions of the Peripheral Nervous System. This quiz covers the divisions of the PNS, sensory receptors, and their roles in transmitting information to and from the Central Nervous System. Prepare to dive into both afferent and efferent pathways of the nervous system.