Perfusion Technology and Techniques

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Which of the following characteristics describes an ideal oxygenator?

Efficient flow pathway (correct)

Minimized surface area for gas and heat exchange

High pressure drop across the membrane

Limited oxygen transfer

Who developed Fick's First Law of Diffusion?

Adolf Fick (correct)

Albert Einstein

Louis Pasteur

Robert Boyle

According to Fick's First Law of Diffusion, the movement of O2 and CO2 across a barrier is in the direction of...

No movement

Higher to lower concentration (correct)

Equal concentration

Lower to higher concentration

Which of the following is NOT a characteristic of an ideal oxygenator?

Limited oxygen transfer Signup and view all the answers

What is the diffusion coefficient (D) in Fick's First Law of Diffusion?

A constant for the particular barrier Signup and view all the answers

What does Fick's First Law of Diffusion tell us about the movement of O2 and CO2 across a barrier?

It is in the direction of higher to lower concentration Signup and view all the answers

What is the equation for Fick's First Law of Diffusion?

$J = -D\frac{d\phi},{dx}$ Signup and view all the answers

What does the diffusion coefficient (D) represent in Fick's First Law of Diffusion?

A constant for the particular barrier Signup and view all the answers

What does the variable J represent in Fick's First Law of Diffusion?

The diffusion flux or amount of substance moved per unit area, per unit time Signup and view all the answers

What does the variable x represent in Fick's First Law of Diffusion?

The length of the barrier Signup and view all the answers

Which of the following statements is true about gas diffusion across a membrane?

Gas diffusion is faster when the gradient across the membrane is higher. Signup and view all the answers

In the Extracorporeal circuit, why is countercurrent flow more efficient for the exchange of molecules or particles across the barrier?

Countercurrent flow allows for movement of molecules or particles throughout the entire length of the system. Signup and view all the answers

What is the priming volume of an oxygenator?

The volume of fluid required to fill the blood phase of the device. Signup and view all the answers

How is the ability of an oxygenator to oxygenate blood expressed?

In the oxygen reference blood flow. Signup and view all the answers

What is the oxygen reference blood flow?

The flow rate of whole blood at normothermia that will increase the oxygen content of venous blood by 45 mL/L of flow. Signup and view all the answers

What is the rated flow or reference flow of an oxygenator?

The maximal recommended flow to achieve adequate gas exchange. Signup and view all the answers

Which of the following is true about concurrent flow in the Extracorporeal circuit?

At the entrance, the concentrations are 100%:0%. Signup and view all the answers

Which of the following is true about countercurrent flow in the Extracorporeal circuit?

The movement of molecules or particles occurs throughout the entire length of the system. Signup and view all the answers

Which of the following is true about gas diffusion across a membrane?

Gas diffusion is slower when the gradient across the membrane is higher. Signup and view all the answers

What is the purpose of the sweep gas flow across the oxygenator in the Extracorporeal circuit?

To efficiently remove CO2 from higher to lower concentrations. Signup and view all the answers