Untitled Quiz
18 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which type of antibiotic is vancomycin?

  • Polypeptide
  • Beta-lactam
  • Glycopeptide (correct)
  • Polyene
  • At what concentration is vancomycin bactericidal to all susceptible bacteria?

  • No specific concentration
  • At its MIC (correct)
  • Below its MIC
  • Above its MIC
  • What problem has arisen due to the development of Vancomycin Resistant enterococci (VRE)?

  • Emergence of a common hospital-acquired infection (correct)
  • Increased effectiveness of vancomycin
  • Decreased toxicity of vancomycin
  • Improved treatment options for MRSA
  • Which antibiotic inhibits cell wall synthesis at an early stage by interfering with bactoprenol?

    <p>Bacitracin</p> Signup and view all the answers

    What characteristic is responsible for the acid-fast staining in mycobacteria?

    <p>Lipid-rich nature</p> Signup and view all the answers

    Which antibiotics are commonly used to treat mycobacterial infections like tuberculosis?

    <p>Isoniazid and Ethambutol</p> Signup and view all the answers

    What is the mechanism of action of D-cycloserine in interfering with bacterial cell wall synthesis?

    <p>Competitively inhibiting L-alanine racemase and D-alanine:D-alanine ligase</p> Signup and view all the answers

    How does Vancomycin inhibit peptidoglycan formation necessary for bacterial cell wall synthesis?

    <p>Preventing the precursors from crossing the cell membrane</p> Signup and view all the answers

    Why can't Glycopeptides like Vancomycin effectively inhibit gram-negative bacteria?

    <p>Their molecular size prevents them from crossing the cell wall</p> Signup and view all the answers

    Which enzymes are responsible for polymerizing glycan chains and catalyzing peptide cross-linking in peptidoglycan macromolecule assembly?

    <p>Transglycosylase and transpeptidase</p> Signup and view all the answers

    What is the role of lipid carrier molecules in peptidoglycan biosynthesis?

    <p>Transporting precursors across the cytoplasmic membrane</p> Signup and view all the answers

    How does Glycopeptide antibiotics like Vancomycin block peptidoglycan synthesis in bacterial cell walls?

    <p>By preventing extension of linear glycan peptides in the cell wall</p> Signup and view all the answers

    What is the mechanism of action of ß-Lactam antibiotics in inhibiting the transpeptidase enzyme?

    <p>They mimic the D-alanyl-D-alanin residues and react covalently with transpeptidase</p> Signup and view all the answers

    Which type of bacteria are ß-Lactam antibiotics generally active against?

    <p>Gram-positive bacteria</p> Signup and view all the answers

    Which of the following antibiotics is NOT active against Pseudomonas aeruginosa?

    <p>Penicillin</p> Signup and view all the answers

    Which group of penicillins is effective against both Gram-negative and Gram-positive bacteria?

    <p>Extended Spectrum Penicillins</p> Signup and view all the answers

    What characteristic makes Extended Spectrum Penicillins different from other penicillins?

    <p>They overcome narrow spectrum problems</p> Signup and view all the answers

    Which of the following is true about Carboxypenicillins like carbenicillin?

    <p>They are not effective against Pseudomonas aeruginosa</p> Signup and view all the answers

    Use Quizgecko on...
    Browser
    Browser