Peptide Display and T Cell Recognition
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Questions and Answers

Which cells are responsible for eliminating cytoplasmic microbes?

  • B lymphocytes
  • CD8+ CTLs (correct)
  • CD4+ helper T cells
  • Macrophages
  • What is the main function of CD4+ T lymphocytes?

  • Killing infected cells
  • Assisting macrophages (correct)
  • Producing antibodies
  • Destroying ingested microbes
  • Which cells are responsible for eliminating intracellular viruses?

  • CD8+ CTLs (correct)
  • Macrophages
  • B lymphocytes
  • CD4+ helper T cells
  • What is the role of antibodies in the immune response?

    <p>Eliminating extracellular microbes</p> Signup and view all the answers

    Which type of antigens can T lymphocytes recognize?

    <p>Both intracellular and extracellular antigens</p> Signup and view all the answers

    What is the function of class I MHC molecules?

    <p>To display cytosolic antigens</p> Signup and view all the answers

    What is the significance of segregating the class I and class II pathways of antigen processing?

    <p>To respond to all types of microbes</p> Signup and view all the answers

    Which type of peptides are considered immunodominant peptides of the antigen?

    <p>Peptides that are covalently modified by chemicals</p> Signup and view all the answers

    What makes it difficult to select a small number of peptides from any microbe that would be immunogenic in a large number of people?

    <p>The enormous polymorphism of MHC molecules in the population</p> Signup and view all the answers

    Which genes are responsible for the lack of response to simple protein antigens in some inbred animals?

    <p>Immune response (Ir) genes</p> Signup and view all the answers

    In what manner do T cells recognize and react against small molecules and metal ions?

    <p>By altering the structure of the peptide-binding cleft of MHC molecules</p> Signup and view all the answers

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