11 Questions
Which cells are responsible for eliminating cytoplasmic microbes?
CD8+ CTLs
What is the main function of CD4+ T lymphocytes?
Assisting macrophages
Which cells are responsible for eliminating intracellular viruses?
CD8+ CTLs
What is the role of antibodies in the immune response?
Eliminating extracellular microbes
Which type of antigens can T lymphocytes recognize?
Both intracellular and extracellular antigens
What is the function of class I MHC molecules?
To display cytosolic antigens
What is the significance of segregating the class I and class II pathways of antigen processing?
To respond to all types of microbes
Which type of peptides are considered immunodominant peptides of the antigen?
Peptides that are covalently modified by chemicals
What makes it difficult to select a small number of peptides from any microbe that would be immunogenic in a large number of people?
The enormous polymorphism of MHC molecules in the population
Which genes are responsible for the lack of response to simple protein antigens in some inbred animals?
Immune response (Ir) genes
In what manner do T cells recognize and react against small molecules and metal ions?
By altering the structure of the peptide-binding cleft of MHC molecules
Test your knowledge on the peptide display function of MHC molecules and its importance in T cell-mediated immunity. Explore the fundamental features and restrictions of T cell recognition in this informative quiz.
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