Peptide Display and T Cell Recognition
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Peptide Display and T Cell Recognition

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@StupendousNovaculite

Questions and Answers

Which cells are responsible for eliminating cytoplasmic microbes?

CD8+ CTLs

What is the main function of CD4+ T lymphocytes?

Assisting macrophages

Which cells are responsible for eliminating intracellular viruses?

CD8+ CTLs

What is the role of antibodies in the immune response?

<p>Eliminating extracellular microbes</p> Signup and view all the answers

Which type of antigens can T lymphocytes recognize?

<p>Both intracellular and extracellular antigens</p> Signup and view all the answers

What is the function of class I MHC molecules?

<p>To display cytosolic antigens</p> Signup and view all the answers

What is the significance of segregating the class I and class II pathways of antigen processing?

<p>To respond to all types of microbes</p> Signup and view all the answers

Which type of peptides are considered immunodominant peptides of the antigen?

<p>Peptides that are covalently modified by chemicals</p> Signup and view all the answers

What makes it difficult to select a small number of peptides from any microbe that would be immunogenic in a large number of people?

<p>The enormous polymorphism of MHC molecules in the population</p> Signup and view all the answers

Which genes are responsible for the lack of response to simple protein antigens in some inbred animals?

<p>Immune response (Ir) genes</p> Signup and view all the answers

In what manner do T cells recognize and react against small molecules and metal ions?

<p>By altering the structure of the peptide-binding cleft of MHC molecules</p> Signup and view all the answers

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