Peptic Ulcer Disease
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Questions and Answers

Where is a duodenal ulcer usually located?

  • Duodenal bulb of the small intestine (correct)
  • Jejunum
  • Stomach
  • Esophagus

Which age group is more commonly affected by gastric ulcers?

  • Teenagers between 13-19 years old
  • Adults between 30-50 years old
  • Children under 10 years old
  • Elderly individuals over 60 years old (correct)

What is the hormone-like substance that keeps blood vessels dilated and stimulates mucus and bicarbonate production in the stomach?

  • Insulin
  • Prostaglandins (PGs) (correct)
  • Thyroid hormone
  • Growth hormone

Which aggressive factor is commonly associated with the development of peptic ulcers?

<p>H. pylori infection (A)</p> Signup and view all the answers

Which factor is considered the first line of defense in protecting the stomach lining?

<p>Bicarbonate production (D)</p> Signup and view all the answers

Which factor plays a role in the pathogenesis of peptic ulcers by attracting inflammatory cells to the mucosa?

<p>Lipopolysaccharide (B)</p> Signup and view all the answers

In the pathogenesis of peptic ulcers, which action decreases mucous and bicarbonate secretion?

<p>Inhibition of cyclooxygenase activity (C)</p> Signup and view all the answers

What is the primary route through which Helicobacter pylori (HP) is spread?

<p>Fecal to oral route (A)</p> Signup and view all the answers

Which population group is at a greater risk of developing NSAID-related complications?

<p>Individuals older than 60 years old (C)</p> Signup and view all the answers

What effect does aspirin have on cyclooxygenase activity in the pathogenesis of peptic ulcers?

<p>Decreases prostaglandin synthesis (C)</p> Signup and view all the answers

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