Peptic Ulcer Disease in Special Populations
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Questions and Answers

What percentage of children and adolescents are reported to experience peptic ulcer bleeding internationally?

  • 2–8% (correct)
  • 0.2–1%
  • 4.4–10%
  • 0.5–4.4%
  • What prompts further assessment for peptic ulcer disease (PUD) in pregnant women?

  • Increased appetite
  • Epigastric discomfort with hematemesis (correct)
  • Nausea and vomiting
  • Weight gain
  • Which co-therapy is commonly used with NSAIDs to lower the risk of PUD in older adults?

  • H2-receptor antagonists (H2RAs) (correct)
  • Antibiotics
  • Proton pump inhibitors (PPIs)
  • Antacids
  • When should treatment for H pylori infection in pregnant women ideally occur?

    <p>After delivery, if possible</p> Signup and view all the answers

    Which finding indicates that a pediatric patient may be at risk for peptic ulcer disease?

    <p>Life-threatening GI bleeding</p> Signup and view all the answers

    Study Notes

    Peptic Ulcer Disease (PUD) in Children and Adolescents

    • The incidence of peptic ulcer bleeding in children and adolescents is between 2% and 8% worldwide.
    • Bleeding occurs in 0.5 to 4.4 per 100,000 children.
    • Carefully assess acutely ill children, especially those in the pediatric intensive care unit with complex chronic diseases, as they may be at risk for PUD.

    PUD in Pregnant Women

    • While nausea and vomiting are common during pregnancy, atypical symptoms like epigastric discomfort, hematemesis, or weight loss warrant further evaluation for PUD.
    • PUD was historically rare during pregnancy but more recent data from routine endoscopy procedures shows an increasing prevalence.
    • Proton pump inhibitors (PPIs) are used to treat PUD during pregnancy.
    • Treatment for H. pylori infection associated with PUD should be delayed until after delivery, if possible.

    PUD in Older Adults

    • PUD is linked to NSAID use in individuals over 65 years old.
    • H2-receptor antagonists (H2RAs) are commonly co-prescribed with NSAIDs to reduce the risk of PUD.
    • High-dose H2RA therapy exhibits greater efficacy than low-dose forms in preventing PUD in NSAID users.
    • Nurses should emphasize the importance of discussing co-therapy with primary healthcare providers (HCPs) to patients taking NSAIDs.

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    Description

    This quiz explores Peptic Ulcer Disease (PUD) in children, pregnant women, and older adults. It highlights the unique epidemiology, symptoms, and treatment considerations for these vulnerable groups. Assess your knowledge on how PUD impacts different stages of life.

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