Podcast
Questions and Answers
What is one of the common etiologies for gastric mucosal injury?
What is one of the common etiologies for gastric mucosal injury?
- Reduced mucosal blood flow
- Normal gastric acid secretion
- Increased mucus and bicarbonate secretion
- Chronic corticosteroid use (correct)
Which factor contributes to disrupting mucosal integrity in the stomach?
Which factor contributes to disrupting mucosal integrity in the stomach?
- Increased mucus production
- Helicobacter pylori infection (correct)
- Enhanced mucosal blood flow
- Normal intrinsic epithelial cell defense
How do nonsteroidal anti-inflammatory drugs (NSAIDs) contribute to stress-related mucosal damage (SRMD)?
How do nonsteroidal anti-inflammatory drugs (NSAIDs) contribute to stress-related mucosal damage (SRMD)?
- Through inhibition of prostaglandin synthesis (correct)
- By increasing mucus production
- By enhancing mucosal blood flow
- By decreasing stomach pH
Which protective factor is involved in maintaining gastroduodenal mucosal integrity?
Which protective factor is involved in maintaining gastroduodenal mucosal integrity?
What is the mechanism by which nonselective NSAIDs, including aspirin, cause gastric mucosal damage?
What is the mechanism by which nonselective NSAIDs, including aspirin, cause gastric mucosal damage?
How does the addition of aspirin affect the ulcer-sparing benefit of a selective COX-2 inhibitor?
How does the addition of aspirin affect the ulcer-sparing benefit of a selective COX-2 inhibitor?
What is the effect of corticosteroids alone on the risk of ulcers and complications?
What is the effect of corticosteroids alone on the risk of ulcers and complications?
Which factor has been linked to an increased risk of peptic ulcer disease, impaired ulcer healing, and ulcer recurrence?
Which factor has been linked to an increased risk of peptic ulcer disease, impaired ulcer healing, and ulcer recurrence?
What is the role of HCl in the stomach?
What is the role of HCl in the stomach?
Which cells release histamine and stimulate HCl secretion in the stomach?
Which cells release histamine and stimulate HCl secretion in the stomach?
What inhibits HCl secretion in the body?
What inhibits HCl secretion in the body?
Which substances increase acid secretion through G cells?
Which substances increase acid secretion through G cells?
How do medications decrease HCl secretion in the body?
How do medications decrease HCl secretion in the body?
What is the main factor affecting peptic ulcer disease (PUD) risk?
What is the main factor affecting peptic ulcer disease (PUD) risk?
