Penicillins: Origin and Clinical Use

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Questions and Answers

What are the two purified compounds of penicillin in clinical use?

  • Penicillin M and penicillin P
  • Penicillin A and penicillin B
  • Penicillin G and penicillin H
  • Penicillin G and penicillin V (correct)

How are most penicillins in clinical use synthesized?

  • By yeast fermentation
  • By Penicillium chrysogenum using deep tank fermentation (correct)
  • By Aspergillus moulds
  • By chemical synthesis only

What was a significant characteristic of penicillins when they were first introduced?

  • They caused allergic reactions in most patients
  • They were effective against many bacterial infections caused by staphylococci and streptococci (correct)
  • They were effective only against viruses
  • They were ineffective against bacteria

Why have many types of bacteria developed resistance to penicillins?

<p>Due to overuse and misuse (B)</p> Signup and view all the answers

What is the typical route of administration for penicillin V?

<p>Oral (A)</p> Signup and view all the answers

Which microorganisms were some of the first to be effectively treated by penicillins?

<p>Staphylococci (A)</p> Signup and view all the answers

Which type of administration is specifically mentioned for penicillin V?

<p>Oral administration (A)</p> Signup and view all the answers

What is the main source of penicillins in clinical use today?

<p>Penicillium chrysogenum (B)</p> Signup and view all the answers

Which of the following is a common method of production for penicillins?

<p>Fermentation (D)</p> Signup and view all the answers

What has been a consequence of extensive use of penicillins?

<p>Development of resistance in many types of bacteria (C)</p> Signup and view all the answers

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