Penicillins and Their Mechanism of Action

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Questions and Answers

Which of the following is a characteristic of penicillins?

  • They inhibit bacteria cell wall synthesis
  • They have the same structure as other antibiotics
  • They are agonists
  • They bind to proteins in the cell walls of bacteria (correct)

What is the main function of penicillins?

  • To enhance bacteria cell division
  • To promote bacteria cell wall synthesis
  • To prevent bacteria cell wall synthesis (correct)
  • To destroy bacteria cell walls

What is true about new forms of penicillin?

  • They have different structures (correct)
  • They are less effective than existing penicillins
  • They are not developed anymore
  • They have the same structures as existing penicillins

Which technique has enabled biochemists to determine the precise structure of enzymes and receptor sites?

<p>Analytical chemistry (B)</p> Signup and view all the answers

What is the composition of the structural fragment of a drug molecule that confers pharmacological activity?

<p>Different functional groups (A)</p> Signup and view all the answers

Which of the following correctly describes the orientation of functional groups in a drug molecule?

<p>Correctly orientated with respect to each other (C)</p> Signup and view all the answers

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Study Notes

Characteristics of Penicillins

  • One characteristic of penicillins is that they inhibit bacterial cell wall synthesis.

Function of Penicillins

  • The main function of penicillins is to inhibit bacterial cell wall synthesis, ultimately killing the bacteria.

New Forms of Penicillin

  • New forms of penicillin have been developed through genetic engineering and other techniques.

Determining Enzyme and Receptor Sites

  • X-ray crystallography has enabled biochemists to determine the precise structure of enzymes and receptor sites.

Pharmacological Activity

  • The pharmacophore is the composition of the structural fragment of a drug molecule that confers pharmacological activity.

Orientation of Functional Groups

  • The functional groups in a drug molecule are oriented in a specific three-dimensional arrangement to interact with the receptor site.

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