Penicillins and Cell Wall Synthesis Inhibition Quiz
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Questions and Answers

Who identified the mold that stopped the growth of staphylococci and was later known as penicillin?

  • Prof Filiz Onat
  • H. Florey
  • E. Chain
  • A. Fleming (correct)

What is the chemical feature of penicillins that makes them cell wall inhibitors?

  • Hydroxyl group connected to thiazolidine ring
  • Sulfoxide group connected to thiazolidine ring
  • Thiazolidine ring connected to beta-lactam ring (correct)
  • Carbonyl group connected to beta-lactam ring

Who played a significant role in turning penicillin into a life-saving drug?

  • H. Florey and E. Chain (correct)
  • E. Chain and Prof Filiz Onat
  • Prof Filiz Onat and A. Fleming
  • A. Fleming and Prof Filiz Onat

What did the team at Oxford University need to process in large quantities to carry out animal experiments and clinical trials?

<p>Mold filtrate (C)</p> Signup and view all the answers

Who discovered that a mold had stopped the growth of staphylococci, leading to the identification of penicillin?

<p>Alexander Fleming (D)</p> Signup and view all the answers

What is the chemical structure feature of penicillins that makes them cell wall inhibitors?

<p>Thiazolidine ring connected to beta-lactam ring (C)</p> Signup and view all the answers

Who, along with colleagues, turned penicillin from a laboratory curiosity into a life-saving drug?

<p>Howard Florey and Ernst Chain (D)</p> Signup and view all the answers

What was the name of the mold identified by Alexander Fleming as having stopped the growth of staphylococci?

<p>Penicillium notatum (B)</p> Signup and view all the answers

What did the team at Oxford University need to process in large quantities for animal experiments and clinical trials related to penicillin?

<p>Mold filtrate (A)</p> Signup and view all the answers

Flashcards

Who discovered penicillin?

Alexander Fleming discovered a mold that inhibited the growth of staphylococci, leading to the identification of penicillin.

What makes penicillin a cell wall inhibitor?

Penicillin's structure contains a thiazolidine ring attached to a beta-lactam ring, which is crucial for its function as a cell wall inhibitor.

Who turned penicillin into a drug?

Howard Florey and Ernst Chain played a pivotal role in transforming penicillin from a lab finding to a life-saving drug.

What did the Oxford team need for penicillin research?

The Oxford team needed large quantities of mold filtrate for their animal experiments and clinical trials on penicillin.

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What mold did Fleming discover?

Penicillin notatum is the specific type of mold identified by Alexander Fleming as inhibiting staphylococci growth.

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What is the key feature for penicillin's function?

The thiazolidine ring connected to the beta-lactam ring in penicillin is essential for its cell wall inhibiting properties.

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Who made penicillin a life-saver?

Howard Florey and Ernst Chain, along with their research team, turned penicillin, initially a lab observation, into a clinically effective drug.

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What was needed for penicillin research?

Mold filtrate, the liquid extracted from the mold, was essential for carrying out animal experiments and clinical trials on penicillin.

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