36 Questions
Which autoimmune condition is characterized by the presence of circulating and/or tissue-bound autoantibodies that target structural components of skin and mucosae?
Pemphigoid group
Which type of immunodeficiency is exemplified by HIV and drugs?
Secondary immunodeficiency
Which oral autoimmune disease is characterized by IgG autoantibodies attacking desmoglein-3 (Dsg 3) leading to acantholysis?
Pemphigus vulgaris
Which oral autoimmune disease is indicated by the presence of superficial ulcers on normally looking mucosa without an inflammatory halo?
Pemphigus vulgaris
Which drug is used as an immunosuppressive therapy for pemphigus vulgaris along with corticosteroids to reduce the side effects of high doses of steroids?
Azathioprine
Which variant of pemphigus vegetans may give rise to 'cerebroform tongue' as a result of oral involvement?
Hallopeau variant
Which condition, more recognized than in the past, reflects haematological malignancy in 66% of cases and can mimic mucocutaneous pemphigoid, erythema multiforme, lichen planus, or chronic graft-versus-host disease?
Paraneoplastic autoimmune multi-organ syndrome
Which of the following is NOT typically associated with the classification of oral ulceration mentioned in the text?
Neurological disorders
What is the most common cause of mouth ulcers according to the classification of oral ulceration in the text?
Recurrent aphthous stomatitis
Which of the following is NOT mentioned as a pathogenic mechanism of immunologically-mediated diseases in the text?
Viral infections
Which type of infection is typically associated with the classification of oral ulceration mentioned in the text?
Viral
What is the aim of the lecture mentioned in the text?
To detail the clinical, diagnostic and therapeutic aspects of immunologically mediated disease
Which of the following reflects an anaemia or neutropenia according to the classification of oral ulceration in the text?
Haematological/gastroenterological
Which of the following is NOT a feature of immunologically-mediated oral ulceration mentioned in the text?
Trauma
What can immunobullous disease affect according to the lecture objectives in the text?
The oral mucosa
What type of disease can Behcet's and FPAPA be categorized as according to the classification of oral ulceration mentioned in the text?
Immunologically-mediated
Which of the following is NOT a typical mechanism of causing mouth ulcers based on the classification of oral ulceration mentioned in the text?
Hormonal changes
Which autoimmune disorder is characterized by ulceration of the tongue, buccal mucosae, and palate with white patches?
Dermatomyositis
Which autoimmune disorder may cause swelling of the tongue, floor of the mouth, and dysphagia due to myositis?
Dermatomyositis
Which hematologic disorder is characterized by antibodies to gastric parietal cells, leading to lack of intrinsic factor and vitamin B12 deficiency?
Pernicious anaemia
In which immunologically-mediated disease does 30% of cases show a tendency for recurrence, especially in winter and spring?
Erythema multiforme
Which condition is characterized by acute, immunologically-mediated, mucocutaneous disease with vesicles and bullae formation?
Erythema multiforme
Which disease is managed with systemic steroids and systemic antibiotics in moderate-severe cases, along with an ophthalmological opinion if the eye is involved?
Erythema multiforme
Which group of diseases is characterized by characteristic oral, skin, and eye lesions?
Immunobullous diseases
Which immunologically-mediated disease tends to be autoimmune in basis and is most likely in middle-to-late aged females?
Oral lichen planus
Which immunologically-driven disease has a small, but real, malignant potential unrelated to its clinical presentation?
Oral lichen planus
When suspecting immunologically mediated oral disease, what should be done with patients?
Refer patients to specialists immediately
Which autoimmune disease is associated with gluten-sensitive enteropathy and presents with painful oral erosions and pruritic papulovesicular eruptions?
IgA Dermatoses
Which autoimmune mucocutaneous disease is characterized by subepithelial bullae separation of the basement membrane zone (BMZ) in histopathology?
Pemphigoid group
Which autoimmune disease is associated with reticular, papular/plaque-like, atrophic, and erosive (ulcerative) clinical types referred to as white Wickham’s striae?
Lichen Planus
Which autoimmune mucocutaneous disease is commonly associated with drugs such as beta-blockers, ACE inhibitors, and oral hypoglycaemics?
Lichen Planus
Which autoimmune mucocutaneous disease is characterized by lesions affecting the palate and presenting with a 'sun ray' and 'honeycomb' patterns?
Lupus erythematosus
Which autoimmune mucocutaneous disease is associated with unilateral lesions often affecting the labial mucosa?
Lupus erythematosus
Which autoimmune disease is described as having a submucosal band-like infiltrate of lymphocytes and histiocytes?
Lichen Planus
Which autoimmune mucocutaneous disease is known for having linear IgA deposits at the basement membrane zone (BMZ)?
IgA Dermatoses
Which autoimmune disease is characterized by ulceration and oral lesions similar to that of oral lichen planus, and often affects the palatal mucosa?
Lupus erythematosus
Test your knowledge about pemphigoid group, an immunologically-mediated disease with auto antibodies attacking the basement membrane zone. This quiz covers topics such as mucous membrane pemphigoid, bullous pemphigoid, autoantibodies, and underlying etiology.
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