Pemphigoid Group Immunologically-Mediated Disease Quiz
36 Questions
0 Views

Pemphigoid Group Immunologically-Mediated Disease Quiz

Created by
@BrighterVitality4568

Podcast Beta

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which autoimmune condition is characterized by the presence of circulating and/or tissue-bound autoantibodies that target structural components of skin and mucosae?

  • Pemphigoid group (correct)
  • Oral lichen planus
  • Erythema multiforme
  • Behcet’s disease

    • Which type of immunodeficiency is exemplified by HIV and drugs?

  • Congenital immunodeficiency
  • Primary immunodeficiency
  • Secondary immunodeficiency (correct)
  • Autoimmune immunodeficiency

    • Which oral autoimmune disease is characterized by IgG autoantibodies attacking desmoglein-3 (Dsg 3) leading to acantholysis?

  • Oral lichen planus
  • Pemphigus vulgaris (correct)
  • Lupus erythematosus
  • Erythema multiforme

    • Which oral autoimmune disease is indicated by the presence of superficial ulcers on normally looking mucosa without an inflammatory halo?

    <p>Pemphigus vulgaris</p> Signup and view all the answers

    Which drug is used as an immunosuppressive therapy for pemphigus vulgaris along with corticosteroids to reduce the side effects of high doses of steroids?

    <p>Azathioprine</p> Signup and view all the answers

    Which variant of pemphigus vegetans may give rise to 'cerebroform tongue' as a result of oral involvement?

    <p>Hallopeau variant</p> Signup and view all the answers

    Which condition, more recognized than in the past, reflects haematological malignancy in 66% of cases and can mimic mucocutaneous pemphigoid, erythema multiforme, lichen planus, or chronic graft-versus-host disease?

    <p>Paraneoplastic autoimmune multi-organ syndrome</p> Signup and view all the answers

    Which of the following is NOT typically associated with the classification of oral ulceration mentioned in the text?

    <p>Neurological disorders</p> Signup and view all the answers

    What is the most common cause of mouth ulcers according to the classification of oral ulceration in the text?

    <p>Recurrent aphthous stomatitis</p> Signup and view all the answers

    Which of the following is NOT mentioned as a pathogenic mechanism of immunologically-mediated diseases in the text?

    <p>Viral infections</p> Signup and view all the answers

    Which type of infection is typically associated with the classification of oral ulceration mentioned in the text?

    <p>Viral</p> Signup and view all the answers

    What is the aim of the lecture mentioned in the text?

    <p>To detail the clinical, diagnostic and therapeutic aspects of immunologically mediated disease</p> Signup and view all the answers

    Which of the following reflects an anaemia or neutropenia according to the classification of oral ulceration in the text?

    <p>Haematological/gastroenterological</p> Signup and view all the answers

    Which of the following is NOT a feature of immunologically-mediated oral ulceration mentioned in the text?

    <p>Trauma</p> Signup and view all the answers

    What can immunobullous disease affect according to the lecture objectives in the text?

    <p>The oral mucosa</p> Signup and view all the answers

    What type of disease can Behcet's and FPAPA be categorized as according to the classification of oral ulceration mentioned in the text?

    <p>Immunologically-mediated</p> Signup and view all the answers

    Which of the following is NOT a typical mechanism of causing mouth ulcers based on the classification of oral ulceration mentioned in the text?

    <p>Hormonal changes</p> Signup and view all the answers

    Which autoimmune disorder is characterized by ulceration of the tongue, buccal mucosae, and palate with white patches?

    <p>Dermatomyositis</p> Signup and view all the answers

    Which autoimmune disorder may cause swelling of the tongue, floor of the mouth, and dysphagia due to myositis?

    <p>Dermatomyositis</p> Signup and view all the answers

    Which hematologic disorder is characterized by antibodies to gastric parietal cells, leading to lack of intrinsic factor and vitamin B12 deficiency?

    <p>Pernicious anaemia</p> Signup and view all the answers

    In which immunologically-mediated disease does 30% of cases show a tendency for recurrence, especially in winter and spring?

    <p>Erythema multiforme</p> Signup and view all the answers

    Which condition is characterized by acute, immunologically-mediated, mucocutaneous disease with vesicles and bullae formation?

    <p>Erythema multiforme</p> Signup and view all the answers

    Which disease is managed with systemic steroids and systemic antibiotics in moderate-severe cases, along with an ophthalmological opinion if the eye is involved?

    <p>Erythema multiforme</p> Signup and view all the answers

    Which group of diseases is characterized by characteristic oral, skin, and eye lesions?

    <p>Immunobullous diseases</p> Signup and view all the answers

    Which immunologically-mediated disease tends to be autoimmune in basis and is most likely in middle-to-late aged females?

    <p>Oral lichen planus</p> Signup and view all the answers

    Which immunologically-driven disease has a small, but real, malignant potential unrelated to its clinical presentation?

    <p>Oral lichen planus</p> Signup and view all the answers

    When suspecting immunologically mediated oral disease, what should be done with patients?

    <p>Refer patients to specialists immediately</p> Signup and view all the answers

    Which autoimmune disease is associated with gluten-sensitive enteropathy and presents with painful oral erosions and pruritic papulovesicular eruptions?

    <p>IgA Dermatoses</p> Signup and view all the answers

    Which autoimmune mucocutaneous disease is characterized by subepithelial bullae separation of the basement membrane zone (BMZ) in histopathology?

    <p>Pemphigoid group</p> Signup and view all the answers

    Which autoimmune disease is associated with reticular, papular/plaque-like, atrophic, and erosive (ulcerative) clinical types referred to as white Wickham’s striae?

    <p>Lichen Planus</p> Signup and view all the answers

    Which autoimmune mucocutaneous disease is commonly associated with drugs such as beta-blockers, ACE inhibitors, and oral hypoglycaemics?

    <p>Lichen Planus</p> Signup and view all the answers

    Which autoimmune mucocutaneous disease is characterized by lesions affecting the palate and presenting with a 'sun ray' and 'honeycomb' patterns?

    <p>Lupus erythematosus</p> Signup and view all the answers

    Which autoimmune mucocutaneous disease is associated with unilateral lesions often affecting the labial mucosa?

    <p>Lupus erythematosus</p> Signup and view all the answers

    Which autoimmune disease is described as having a submucosal band-like infiltrate of lymphocytes and histiocytes?

    <p>Lichen Planus</p> Signup and view all the answers

    Which autoimmune mucocutaneous disease is known for having linear IgA deposits at the basement membrane zone (BMZ)?

    <p>IgA Dermatoses</p> Signup and view all the answers

    Which autoimmune disease is characterized by ulceration and oral lesions similar to that of oral lichen planus, and often affects the palatal mucosa?

    <p>Lupus erythematosus</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser