Peak Level and Serum Concentrations Quiz

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52 Questions

When collecting blood culture samples with a butterfly, which sample is aerobic and which is anaerobic?

The first sample is aerobic, the second is anaerobic

What is the purpose of a blood culture?

To detect the presence of microorganisms in the blood

What issue can arise from arthritis in geriatric patients?

Difficulty straightening arm or fingers

What is a common risk factor for geriatric patients on anticoagulant therapy?

Increased risk of hematoma

What is therapeutic drug monitoring (TDM) used for?

To adjust drug dosing

Why are aminoglycoside antibiotics like gentamicin and tobramycin carefully monitored?

Because they have short half-lives

When is the peak level usually collected in therapeutic drug monitoring?

30 minutes after the dose is administered

What does the requisition specify in therapeutic drug monitoring?

The actual collection time

Why is it important to maintain constant therapeutic plasma drug levels?

To prevent toxicity and maintain effectiveness

Why do patients differ greatly in how they metabolize medications?

Because of differences in metabolism rate

What is the recommended technique to locate veins for venipuncture in geriatric patients?

Gently massage the area to warm it up

Why is the antecubital fossa not always the best site for venipuncture?

It has more fragile veins in geriatric patients

What should be done after locating the appropriate vein for venipuncture?

Ensure the area is sufficiently cleaned

Why is it advised to use a smaller needle or butterfly in geriatric patients?

To cause less pain

What should be done after completing a venipuncture in geriatric patients?

Apply pressure longer to ensure bleeding has stopped

Why do patients with certain conditions require regular blood testing over an extended period?

To keep track of their health status

What can happen to commonly used sites for blood draws in patients needing regular blood testing over extended periods?

Veins become hardened and difficult to penetrate

Why might the skin of patients requiring frequent blood draws become delicate and easily torn?

Because of trauma from frequent needle puncture

What is the correct order of collecting blood culture samples with a butterfly?

Aerobic first, then anaerobic

Why should you add a short blood sample to the aerobic bottle?

Because most significant pathogens are aerobes

How should you prepare the site for obtaining a valid blood culture specimen?

Scrub vigorously with alcohol in a circular motion

What should be done after cleaning the site for a blood culture?

Allow the site to dry for 1 minute

Why should you avoid touching the site after it has been cleaned?

To prevent contamination from skin bacteria

Why is it recommended to use a butterfly for blood sample collection?

To reduce clotting risk

What is the purpose of culturing the blood specimen onto appropriate media?

To identify pathogens present

Why is the peak level in therapeutic drug monitoring typically drawn a few hours after administering the drug?

To calculate how much drug was actually absorbed

What is the primary reason for promptly obtaining therapeutic drug monitoring (TDM) results?

To determine the timing and dosage of the drug

What is the role of insulin in controlling glucose levels in patients with dysfunctional glucose metabolism?

It helps glucose enter cells

Why are most therapeutic drug monitoring samples collected in a red top tube?

To prevent interference from gel in serum separator tubes

What happens when cells do not respond to insulin in patients with dysfunctional glucose metabolism?

Diabetes may occur

Why is careful attention to timing and labeling important in therapeutic drug monitoring?

To ensure accurate dosage determination

What is the key determinant of when the peak level occurs after administering a drug?

Characteristics of the drug

Why is timely collection of TDM results crucial for pharmacy decisions?

To adjust drug timing and dosages

Why do veins become harder to anchor in geriatric patients?

Due to a reduction in elasticity

What may lead to the narrowing of vessels in geriatric patients?

Atherosclerosis

Why do arteries tend to be closer to the surface in geriatric patients?

Loss of muscle tissue

What effect does visual impairment have on geriatric patients during blood draws?

Impairs compliance with requests

Why is it important not to mistake an artery near the surface for a vein in geriatric patients?

Arteries can be pulsing

How should healthcare professionals begin speaking with geriatric patients during encounters?

Speaking slowly and deliberately

What issue may arise if the skin is not held taut during venipuncture in geriatric patients?

Veins moving from their locations

How does the thickness of the skin impact the visibility of veins in geriatric patients?

Thinner skin makes veins less visible

What is the recommended way to prepare the arm before finding a vein for venipuncture?

Massage the area gently for several minutes

Why may a smaller needle or butterfly be recommended for geriatric patients during venipuncture?

To avoid rolling of fragile veins

What should you avoid doing when trying to locate a vein for venipuncture?

Probing the skin

Why may patients requiring extended blood draws experience difficulty with commonly used sites?

Because of frequent needle punctures causing damage

What can happen if a patient's skin from frequent needle punctures becomes delicate and easily torn?

The patient may develop scars

Why is it important to apply pressure longer after completing a venipuncture in geriatric patients?

To stop excessive bleeding

What is a risk associated with hardening of veins in patients needing regular blood draws over extended periods?

Veins becoming difficult to penetrate with needles

Why should you not "slap" the arm to find a vein for venipuncture?

To prevent unnecessary discomfort to the patient

What is septicemia?

A lifethreatening infection caused by rapid multiplication of pathogens in the bloodstream

Why is it necessary to collect a blood culture before administering antimicrobial therapy?

To decrease false negatives due to low organism numbers

What is the meaning of bacteremia?

The presence of bacteria in the blood

Test your knowledge on peak levels and serum concentrations of drugs. Learn about the importance of correct timing for drawing peak levels and accurate labeling in therapeutic drug monitoring.

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