Plasma Concentration-Time Profiles and Drug Effects Quiz

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Questions and Answers

Which of the following best describes the therapeutic window?

  • The concentration of drug needed to produce a toxic effect
  • The ratio between the toxic and therapeutic doses
  • The average rate of drug absorption
  • The difference between the onset time and the time for the drug to decline back to the MEC (correct)

What does the peak plasma level represent?

  • The time required for the drug to reach the MEC
  • The average rate of drug absorption (correct)
  • The ratio between the toxic and therapeutic doses
  • The concentration of drug needed to produce a toxic effect

What is the therapeutic index?

  • The concentration of drug needed to produce a toxic effect
  • The average rate of drug absorption
  • The ratio between the toxic and therapeutic doses (correct)
  • The difference between the onset time and the time for the drug to decline back to the MEC

What does the area under the curve represent?

<p>The amount of drug absorbed systemically (B)</p> Signup and view all the answers

What does the onset time refer to?

<p>The time required for the drug to reach the MEC (B)</p> Signup and view all the answers

Which of the following best describes the process of elimination for a drug?

<p>Both excretion and biotransformation (D)</p> Signup and view all the answers

What does MEC stand for in the context of drug concentration?

<p>Minimum Effective Concentration (B)</p> Signup and view all the answers

What is the relationship between drug absorption and elimination?

<p>Absorption is faster than elimination (C)</p> Signup and view all the answers

What are the three distinct cut-off points along the y-axis representing plasma-drug concentration?

<p>MTC, MSC, and MEC (D)</p> Signup and view all the answers

What happens to a drug after it is absorbed into the systemic circulation?

<p>It gets distributed to most tissues in the body (C)</p> Signup and view all the answers

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