Pathophysiology of Type 2 Diabetes
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Questions and Answers

What are the characteristics of type 2 diabetes?

  • Peripheral insulin resistance and inadequate insulin secretion (correct)
  • Peripheral insulin sensitivity and inadequate insulin secretion
  • Peripheral insulin resistance and excessive insulin secretion
  • Peripheral insulin sensitivity and excessive insulin secretion

What is the role of excess glucagon in type 2 diabetes?

  • It leads to decreased glucose transport into muscle cells
  • It leads to increased breakdown of fat
  • It leads to hyperglucagonemia and consequent hyperglycemia (correct)
  • It causes hyperinsulinemia

What is the effect of high fasting plasma concentrations of 3 amino acids on the risk of future diabetes?

  • Slight increase in the risk of future diabetes
  • No effect on the risk of future diabetes
  • At least 4-fold higher risk of future diabetes (correct)
  • Decreased risk of future diabetes

What has been attributed to the insulin resistance in type 2 diabetes?

<p>Elevated levels of free fatty acids and proinflammatory cytokines in plasma (B)</p> Signup and view all the answers

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