Pathophysiology of Type 2 Diabetes

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4 Questions

What is the main characteristic of type 2 diabetes?

Combination of peripheral insulin resistance and inadequate insulin secretion

What leads to decreased glucose transport into muscle cells in type 2 diabetes?

Elevated levels of free fatty acids and proinflammatory cytokines in plasma

What is the impact of the lost reciprocal relationship between alpha and beta cells in type 2 diabetes?

Hyperglycemia due to hyperglucagonemia

What is the relationship between high fasting plasma concentrations of certain amino acids and the risk of future diabetes?

The risk of future diabetes increases

Test your knowledge of the pathophysiology of type 2 diabetes, including peripheral insulin resistance, inadequate insulin secretion, elevated free fatty acids, proinflammatory cytokines, and the role of glucagon. Understand the mechanisms behind decreased glucose transport into muscle cells and elevated hepatic glucose production.

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