Pathophysiology of Type 2 Diabetes

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Questions and Answers

What is the main characteristic of type 2 diabetes?

  • Peripheral insulin resistance only
  • Combination of peripheral insulin resistance and inadequate insulin secretion (correct)
  • Elevated hepatic glucose production
  • Inadequate insulin secretion only

What leads to decreased glucose transport into muscle cells in type 2 diabetes?

  • Elevated levels of free fatty acids and proinflammatory cytokines in plasma (correct)
  • Increased breakdown of fat
  • Low levels of glucagon
  • High levels of insulin

What is the impact of the lost reciprocal relationship between alpha and beta cells in type 2 diabetes?

  • Decreased glucagon secretion
  • Increased insulin secretion
  • Hyperglycemia due to hyperglucagonemia (correct)
  • Normalization of blood glucose levels

What is the relationship between high fasting plasma concentrations of certain amino acids and the risk of future diabetes?

<p>The risk of future diabetes increases (A)</p>
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