Pathophysiology of Psychosis Quiz

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Questions and Answers

What is the primary cause of positive symptoms in schizophrenia?

  • Increased dopamine activity in the tuberoinfundibular pathway
  • Dopamine blockade leading to increased prolactin
  • Excess dopamine activity in the mesolimbic pathway (correct)
  • Dopamine receptor blockade in the nigrostriatal pathway
  • Decreased dopamine activity in the mesocortical pathway

Which dopaminergic tract is implicated in the development of negative symptoms in schizophrenia?

  • Nigrostriatal
  • Mesolimbic
  • Mesocortical (correct)
  • Tuberoinfundibular
  • None of the above

What is the effect of dopamine receptor blockade in the nigrostriatal pathway?

  • Negative symptoms
  • Tuberoinfundibular pathway activation
  • Positive symptoms
  • Increased prolactin levels
  • Extrapyramidal symptoms (EPS) (correct)

Which type of symptoms in schizophrenia is associated with dopamine receptor hypofunction in the mesocortical pathway?

<p>Negative symptoms (C)</p> Signup and view all the answers

What is the consequence of dopamine blockade in the tuberoinfundibular pathway?

<p>Increased prolactin levels (D)</p> Signup and view all the answers

What is the primary cause of positive symptoms in schizophrenia?

<p>Excess/distortion of normal function associated with dopamine receptor hyperactivity in the mesolimbic pathway (B)</p> Signup and view all the answers

What is the consequence of dopamine blockade in the tuberoinfundibular pathway?

<p>Increased prolactin levels (C)</p> Signup and view all the answers

What type of symptoms are associated with dopamine receptor hypofunction in the mesocortical pathway?

<p>Decrease/absence of normal function associated with dopamine receptor hypofunction in the mesocortical pathway (D)</p> Signup and view all the answers

What is the effect of dopamine receptor blockade in the nigrostriatal pathway?

<p>Extrapyramidal symptoms (C)</p> Signup and view all the answers

What is the primary cause of negative symptoms in schizophrenia?

<p>Decrease/absence of normal function associated with dopamine receptor hypofunction in the mesocortical pathway (E)</p> Signup and view all the answers

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