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Questions and Answers
What is the therapeutic lag in schizophrenia patients despite blocking receptors within 30 mins?
What is the therapeutic lag in schizophrenia patients despite blocking receptors within 30 mins?
- 1-2 months
- 4-6 weeks
- 2-3 months (correct)
- 6-8 weeks
Which symptoms are not improved among the lucky 1/3 where antipsychotics work?
Which symptoms are not improved among the lucky 1/3 where antipsychotics work?
- Positive symptoms
- Affective symptoms
- Negative symptoms (correct)
- Cognitive symptoms
What is the main limitation of the dopamine hypothesis in schizophrenia treatment?
What is the main limitation of the dopamine hypothesis in schizophrenia treatment?
- Lack of d2 antagonists targeting striatum
- High drug potency
- Only 1/3 efficacy in schizophrenia patients (correct)
- Inability to target PFC dopamine levels
What accounts for cognitive decline in schizophrenia according to the text?
What accounts for cognitive decline in schizophrenia according to the text?
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What is the primary function of chlorpromazine in treating schizophrenia?
What is the primary function of chlorpromazine in treating schizophrenia?
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Where are D2 dopamine receptors most prevalent?
Where are D2 dopamine receptors most prevalent?
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What is the relationship between drug potency and affinity for D2 receptors?
What is the relationship between drug potency and affinity for D2 receptors?
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What is a limitation of the dopamine hypothesis in explaining schizophrenia?
What is a limitation of the dopamine hypothesis in explaining schizophrenia?
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