Pathophysiology of Pain: Anatomy of Pain and Somatosensory System
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Questions and Answers

Which type of neurons transmit pain signals from the periphery to the spinal cord?

  • A-delta and C fibers
  • Motor neurons
  • First-order neurons (correct)
  • Third-order neurons
  • What is the primary function of the periaqueductal gray matter?

  • Inhibition of pain transmission (correct)
  • Transmission of pain signals to the brain
  • Processing of sensory information
  • Regulation of motor function
  • What is the term for the perception of an ordinarily non-noxious stimulus as pain?

  • Allodynia (correct)
  • Hyperalgesia
  • Dysesthesia
  • Hypoalgesia
  • What is the term for the absence of all sensation?

    <p>Anesthesia</p> Signup and view all the answers

    Which part of the brain receives fibers from third-order neurons?

    <p>Postcentral gyrus of the parietal cortex</p> Signup and view all the answers

    What is the term for pain in the distribution of a nerve or a group of nerves?

    <p>Neuralgia</p> Signup and view all the answers

    What is the term for an abnormal sensation perceived without an apparent stimulus?

    <p>Paresthesia</p> Signup and view all the answers

    What is the term for the presence of hyperesthesia, allodynia, and hyperalgesia?

    <p>Hyperapthia</p> Signup and view all the answers

    What is the primary function of neutrophils in response to invading microbes?

    <p>To engulf and kill invading microbes and release more inflammatory cytokines</p> Signup and view all the answers

    What is the primary cause of pain in patients who experience psychogenic pain?

    <p>A psychological problem or disturbance</p> Signup and view all the answers

    What is somatization disorder characterized by?

    <p>Physical symptoms of a medical condition that cannot be explained</p> Signup and view all the answers

    What percentage of children and adolescents are affected by chronic pain worldwide?

    <p>20-35%</p> Signup and view all the answers

    What type of pain is often made worse by touch, movement, emotions, and temperature changes?

    <p>Central pain</p> Signup and view all the answers

    What is the primary characteristic of malingering?

    <p>Intentional production of physical or psychological symptoms</p> Signup and view all the answers

    What is a predictor of the development of chronic postsurgical pain in children?

    <p>Pain unpleasantness</p> Signup and view all the answers

    What is a characteristic of superficial somatic pain?

    <p>Sharp, pricking, throbbing, burning</p> Signup and view all the answers

    What is the mechanism of central pain?

    <p>Lesions in the brain or nervous system</p> Signup and view all the answers

    What is the primary difference between inflammatory pain and central pain?

    <p>The location of the lesion or injury</p> Signup and view all the answers

    What is a characteristic of visceral nociceptive pain?

    <p>Dull and poorly localized</p> Signup and view all the answers

    What is a subtype of visceral nociceptive pain?

    <p>Localized parietal pain</p> Signup and view all the answers

    What is the primary characteristic of chronic pain?

    <p>Pain secondary to changes in the nervous system</p> Signup and view all the answers

    What is a common symptom associated with visceral pain?

    <p>Nausea and vomiting</p> Signup and view all the answers

    What is a predictor of the persistence of chronic postsurgical pain in children?

    <p>Anxiety sensitivity</p> Signup and view all the answers

    What type of pain is characterized by a defined time period?

    <p>Ongoing time-limited pain</p> Signup and view all the answers

    Which component of pain refers to the neural response to traumatic or noxious stimuli?

    <p>Nociception</p> Signup and view all the answers

    What is true about the relationship between nociception and pain?

    <p>Not all pain results from nociception</p> Signup and view all the answers

    Where does the process of perceiving pain begin?

    <p>The dorsal horn of the spinal cord</p> Signup and view all the answers

    What is suffering, in the context of pain?

    <p>A negative affective response generated in the brain</p> Signup and view all the answers

    What is the primary focus of most commonly employed assessment strategies for pain?

    <p>Pain behaviors</p> Signup and view all the answers

    What can trigger pain, according to the perception of pain component?

    <p>The anticipation of potential pain</p> Signup and view all the answers

    What is the relationship between pain and suffering?

    <p>Suffering is a distinct component of the pain experience</p> Signup and view all the answers

    What is a common manifestation of pain in patients who are non-verbal or unable to describe their pain?

    <p>Vocalizations of distress</p> Signup and view all the answers

    What is a physiologic effect of pain on the cardiovascular system?

    <p>Hypertension</p> Signup and view all the answers

    What is a consequence of chronic pain on the immune system?

    <p>Increased risk of infection</p> Signup and view all the answers

    What is a long-term impact of chronic pain on the nervous system?

    <p>Plasticity leading to sensitization</p> Signup and view all the answers

    What is a gastrointestinal effect of pain?

    <p>Hypersecretion of gastric acid</p> Signup and view all the answers

    What is a benefit of multimodal anesthesia?

    <p>Pain relief through intervening at multiple points</p> Signup and view all the answers

    What is a hematologic effect of pain?

    <p>Increased platelet adhesiveness</p> Signup and view all the answers

    What is a respiratory effect of pain?

    <p>Increased total body O2 consumption</p> Signup and view all the answers

    What is an advantage of using ultrasound-guided regional anesthesia techniques?

    <p>Allows for improved visualization of nerve location and surrounding anatomic structures</p> Signup and view all the answers

    What is a limitation of ultrasound-guided regional anesthesia techniques?

    <p>Adds an additional layer of complexity</p> Signup and view all the answers

    What is a benefit of using ultrasound-guided regional anesthesia techniques?

    <p>Improves the block quality and onset time</p> Signup and view all the answers

    What is a characteristic of traditional nerve stimulation techniques?

    <p>Relies heavily on anatomic landmarks</p> Signup and view all the answers

    What is an advantage of using ultrasound-guided regional anesthesia techniques over traditional techniques?

    <p>Improves the ability to differentiate perineural injection from unintentional epineural injection</p> Signup and view all the answers

    What is a potential drawback of using ultrasound-guided regional anesthesia techniques?

    <p>Adds an additional layer of complexity</p> Signup and view all the answers

    What is a benefit of using ultrasound-guided regional anesthesia techniques in terms of needle advancement?

    <p>Provides real-time imaging of needle advancement</p> Signup and view all the answers

    What is an advantage of using ultrasound-guided regional anesthesia techniques in terms of learning curve?

    <p>Accelerates the learning curve for regional anesthesia</p> Signup and view all the answers

    What is the recommended length of a needle for an interscalene brachial plexus block?

    <p>25 mm (1 in) to 50 mm (2 in)</p> Signup and view all the answers

    What is the term for the plane that divides the body into left and right halves?

    <p>Sagittal plane</p> Signup and view all the answers

    What is a benefit of continuous infusion catheters in pain management?

    <p>Prolonged analgesia</p> Signup and view all the answers

    What is the primary purpose of in-plane needle guidance?

    <p>To visualize the needle tip</p> Signup and view all the answers

    What is the recommended length of a needle for a lumbar plexus block?

    <p>50 mm (2 in) to 100 mm (4 in)</p> Signup and view all the answers

    What is the benefit of practice in ultrasound-guided regional anesthesia?

    <p>All of the above</p> Signup and view all the answers

    What is the recommended length of a needle for a sciatic block with an anterior approach?

    <p>100 mm (4 in) to 150 mm (6 in)</p> Signup and view all the answers

    What is a benefit of single-injection nerve blocks?

    <p>Faster onset of analgesia</p> Signup and view all the answers

    What is the term for the view created when the structures are at a right angle to the probe?

    <p>Cross-sectional view</p> Signup and view all the answers

    What is the purpose of out-of-plane needle guidance?

    <p>To direct the needle at the target perpendicularly</p> Signup and view all the answers

    What is the recommended length of a needle for a popliteal block with a posterior approach?

    <p>25 mm (1 in) to 50 mm (2 in)</p> Signup and view all the answers

    What is a benefit of continuous infusion catheters in rehabilitation?

    <p>Improved ability to participate in rehabilitation</p> Signup and view all the answers

    What is the term for the plane that divides the body into front and back halves?

    <p>Frontal plane</p> Signup and view all the answers

    What is the recommended length of a needle for a cervical plexus block?

    <p>25 mm (1 in) to 50 mm (2 in)</p> Signup and view all the answers

    What is the benefit of the 3 probe maneuvers (A, R, T) in ultrasound-guided regional anesthesia?

    <p>All of the above</p> Signup and view all the answers

    What is the primary focus of clinical application in ultrasound-guided regional anesthesia?

    <p>Matching the appropriate mode of pain control with the surgery</p> Signup and view all the answers

    What is a potential cause of nerve injury following a peripheral nerve block?

    <p>A hematoma compressing a nerve</p> Signup and view all the answers

    What is the primary focus of the anesthesia team in the preoperative management phase?

    <p>Patient selection and education</p> Signup and view all the answers

    What does the acronym SCANNING stand for in the context of anesthesia?

    <p>Supplies, Comfortable positioning, Ambiance, Nominate a transducer, Name and procedure, Infection control, Note lateral/medial side on screen, Gain and depth adjustments</p> Signup and view all the answers

    What is the primary reason for following up with patients after a peripheral nerve block?

    <p>To monitor for potential complications</p> Signup and view all the answers

    What is a key component of the anesthesia team's technique in regional anesthesia?

    <p>Proficiency of the clinician</p> Signup and view all the answers

    What is the primary goal of preoperative management in regional anesthesia?

    <p>To prepare the patient for the procedure</p> Signup and view all the answers

    What is a critical aspect of postoperative management in regional anesthesia?

    <p>Monitoring for potential complications</p> Signup and view all the answers

    What is the primary responsibility of the anesthesia team in regional anesthesia?

    <p>To manage the patient's pain and comfort during and after the procedure</p> Signup and view all the answers

    What is a characteristic of cryoneurolysis?

    <p>It is similar in technique to ultrasound-guided peripheral nerve blockade.</p> Signup and view all the answers

    What is the primary advantage of cryoneurolysis over other treatments?

    <p>It is not specified in the content.</p> Signup and view all the answers

    What is the purpose of cryoneurolysis?

    <p>To treat acute pain.</p> Signup and view all the answers

    What is the name of the nerve that was treated with percutaneous cryoneurolysis in a pilot study?

    <p>Lateral femoral cutaneous nerve.</p> Signup and view all the answers

    Where is cryoneurolysis typically performed?

    <p>In the OR, IR, or procedure room.</p> Signup and view all the answers

    What is the level of sedation required for cryoneurolysis?

    <p>Sedation not necessarily required.</p> Signup and view all the answers

    What is the name of the device used for cryoneurolysis?

    <p>Novel cryoneurolysis device.</p> Signup and view all the answers

    Who wrote a narrative review on cryoneurolysis and percutaneous peripheral nerve stimulation?

    <p>Finneran IV, John J.</p> Signup and view all the answers

    What is the primary goal of incorporating UGRA into clinical practice?

    <p>To reduce the use of opioids in post-operative pain management</p> Signup and view all the answers

    According to the ASA Multimodal Guidelines, what should be considered after thoughtful consideration of the risks and benefits for the individual patient?

    <p>Therapeutic options such as central regional opioids, systemic opioid PCA, and peripheral regional techniques</p> Signup and view all the answers

    What is the benefit of using ultrasound-guided regional anesthesia techniques in terms of needle advancement?

    <p>Real-time visualization of needle placement</p> Signup and view all the answers

    What is the primary focus of the clinical goals outlined in the course objectives?

    <p>Treating pain aggressively</p> Signup and view all the answers

    What is the advantage of using ultrasound-guided regional anesthesia techniques over traditional techniques?

    <p>Real-time visualization of needle placement</p> Signup and view all the answers

    What is the primary characteristic of the course objectives outlined in the content?

    <p>Focusing on the essential principles of ultrasound in regional anesthesia</p> Signup and view all the answers

    What is the recommended approach to pain management according to the ASA Multimodal Guidelines?

    <p>Multimodal pain management</p> Signup and view all the answers

    What is the benefit of integrating non-opioid related therapies into clinical practice?

    <p>Reduced risk of opioid-related adverse effects</p> Signup and view all the answers

    What is the recommended needle length for a cervical plexus block?

    <p>50 mm (2 in)</p> Signup and view all the answers

    What is a benefit of continuous infusion catheters in pain management?

    <p>Prolonged analgesia</p> Signup and view all the answers

    What is the primary goal of multimodal pain management?

    <p>To provide around-the-clock analgesia</p> Signup and view all the answers

    What is the primary mechanism of regional anesthesia?

    <p>Blockade of nerve impulse conduction</p> Signup and view all the answers

    What is the recommended needle length for a thoracic paravertebral block?

    <p>90 mm (3.5-4 in)</p> Signup and view all the answers

    What is the recommended approach to pain management, according to the American Society of Anesthesiologists?

    <p>Multimodal therapy with COXIBs, NSAIDs, or acetaminophen</p> Signup and view all the answers

    What is the recommended needle length for a sciatic block using the anterior approach?

    <p>150 mm (6 in)</p> Signup and view all the answers

    What is the benefit of using regional anesthesia techniques in pain management?

    <p>Improved pain relief with fewer side effects</p> Signup and view all the answers

    What is a benefit of using ultrasound-guided regional anesthesia techniques?

    <p>Improved patient satisfaction</p> Signup and view all the answers

    What is a characteristic of regional anesthesia?

    <p>Temporary analgesia and loss of sensory function</p> Signup and view all the answers

    What is the recommended needle length for a lumbar paravertebral block?

    <p>100 mm (4 in)</p> Signup and view all the answers

    What is the recommended needle length for an axillary brachial plexus block?

    <p>50 mm (2 in)</p> Signup and view all the answers

    What is the recommended approach to pain management in patients at high risk of respiratory depression?

    <p>Multimodal therapy with non-opioid analgesics</p> Signup and view all the answers

    What is a benefit of using ultrasound-guided regional anesthesia techniques?

    <p>Higher success rates and fewer complications</p> Signup and view all the answers

    What is the recommended needle length for an infraclavicular brachial plexus block?

    <p>100 mm (4 in)</p> Signup and view all the answers

    What is the primary focus of the American Society of Anesthesiologists' guidelines for acute pain management?

    <p>Optimizing multimodal pain management</p> Signup and view all the answers

    What is crucial to follow after a patient receives regional anesthesia?

    <p>Monitoring until sensory and motor function return</p> Signup and view all the answers

    What could be the cause of a nerve injury following a peripheral nerve block?

    <p>Tight bandage or hematoma compressing a nerve</p> Signup and view all the answers

    What is essential for success in regional anesthesia?

    <p>All of the above</p> Signup and view all the answers

    What does the acronym SCANNING stand for in regional anesthesia?

    <p>Supplies, Comfortable positioning, Ambiance, Name and procedure, Nominate a transducer, Infection control, Note lateral/medial side on screen, Gain and depth adjustments</p> Signup and view all the answers

    Why is it essential to monitor patients who receive regional anesthesia?

    <p>To monitor until sensory and motor function return</p> Signup and view all the answers

    What is crucial in the management of patients receiving regional anesthesia?

    <p>All of the above</p> Signup and view all the answers

    What is essential for the anesthesia team when performing regional anesthesia?

    <p>All of the above</p> Signup and view all the answers

    Why is continuous monitoring essential after regional anesthesia?

    <p>To monitor until sensory and motor function return</p> Signup and view all the answers

    What is the primary benefit of programmed intermittent bolus over continuous epidural infusion for labor analgesia?

    <p>Fewer side effects with similar analgesic efficacy</p> Signup and view all the answers

    What is the primary advantage of liposomal bupivacaine infiltration over interscalene nerve block for total shoulder arthroplasty?

    <p>Similar pain relief with reduced risk of systemic toxicity</p> Signup and view all the answers

    What is the primary benefit of continuous interscalene block over single-injection interscalene block for major shoulder surgery?

    <p>Improved analgesic efficacy with reduced risk of nerve damage</p> Signup and view all the answers

    What is the primary advantage of programmed intermittent bolus over continuous infusion for peripheral nerve catheters?

    <p>Similar analgesic efficacy with reduced risk of systemic toxicity</p> Signup and view all the answers

    What is the primary benefit of local infiltration over interscalene nerve block for total shoulder arthroplasty?

    <p>Similar pain relief with reduced risk of systemic toxicity</p> Signup and view all the answers

    What is the primary advantage of continuous infusion over programmed intermittent bolus for peripheral nerve catheters?

    <p>Reduced risk of bleeding with similar analgesic efficacy</p> Signup and view all the answers

    What is the primary benefit of liposomal bupivacaine infiltration over continuous interscalene block for total shoulder arthroplasty?

    <p>Similar pain relief with reduced risk of systemic toxicity</p> Signup and view all the answers

    What is the primary advantage of programmed intermittent bolus over continuous infusion for labor analgesia?

    <p>Similar analgesic efficacy with reduced risk of systemic toxicity</p> Signup and view all the answers

    Study Notes

    Anatomy of Pain

    • The somatosensory system is composed of peripheral nervous system, spinal cord, and brain.
    • Afferent neurons, A-delta and C fibers, transmit pain signals to the spinal cord.
    • The spinal cord has ascending and descending pathways that process pain information.
    • The somatosensory cortex, thalamus, and brain process pain information.

    First-Order Neurons

    • First-order neurons transmit pain signals from the periphery to the spinal cord.

    Ascending Pathways

    • Ascending pathways transmit pain signals from the spinal cord to the brain.
    • The periaqueductal gray matter is a key structure in the brain that initiates pain inhibition.

    Third-Order Neurons

    • Third-order neurons transmit pain signals from the thalamus to the cortex.

    Common Pain Terms

    • Allodynia: perception of non-noxious stimuli as pain.
    • Analgesia: absence of pain perception.
    • Anesthesia: absence of all sensation.
    • Anesthesia dolorosa: pain in an area that lacks sensation.
    • Dysesthesia: unpleasant or abnormal sensation with or without stimuli.
    • Hyperalgesia: increased response to noxious stimuli.
    • Hyperesthesia: increased response to mild stimuli.
    • Hyperapthia: presence of hyperesthesia, allodynia, and hyperalgesia.
    • Hypoalgesia: diminished response to noxious stimuli.
    • Hypoesthesia: reduced cutaneous sensation.
    • Neuralgia: pain in the distribution of a nerve or group of nerves.
    • Paresthesia: abnormal sensation perceived without stimuli.
    • Radiculopathy: functional abnormality of one or more nerve roots.

    Classification of Pain

    • Etiology of pain: considering the anticipated tissue damage secondary to a procedure.
    • Duration of pain: chronic pain lasts more than 3 months.

    Mechanism of Pain

    • Nociceptive pain: arises from tissue damage or inflammation.
    • Somatic nociceptive pain: superficial (sharp, pricking) or deep (dull, aching).
    • Visceral nociceptive pain: arises from internal organs, often poorly localized.
    • Neuropathic pain: arises from nerve damage or dysfunction.
    • Inflammatory pain: arises from inflammation and tissue damage.
    • Psychogenic pain: arises from psychological or emotional factors.
    • Central pain: arises from lesions in the brain or spinal cord.

    Associated Emotional Disorders

    • Somatization disorder: physical symptoms cannot be explained, resulting in distress and impairment.
    • Conversion disorder: symptoms suggest a medical condition but are not explainable.
    • Hypochondriasis: prolonged fear of having a serious illness.
    • Malingering: intentional production of physical or psychological symptoms.
    • Substance-related disorders: habitual misuse of prescribed or illicit substances.

    Physiologic Effects of Pain

    • Cardiovascular: hypertension, tachycardia, increased SVR.
    • Respiratory: increased O2 consumption, CO2 production, and minute ventilation.
    • GI and urinary: decreased motility, hypersecretion of gastric acid, nausea, vomiting, and constipation.
    • Hematologic: increased platelet adhesiveness, reduced fibrinolysis, and hypercoagulability.
    • Endocrine: increased catabolic hormones, decreased anabolic hormones, and development of negative nitrogen balance.
    • Immune: predisposes to infection.

    Long Term Impact of Pain

    • Plasticity results in alterations in neuronal structure, interneuronal connections, and neurotransmitters.
    • Leads to sensitization and wind-up phenomenon.

    Multimodal Anesthesia

    • Intervene at multiple points in the pain pathway to reduce pain transmission.

    Motor Response

    • Disappears after injection of local anesthetic or saline
    • PNS does not prevent intravascular, intraneural, or pleural puncture

    Ultrasound-Guided Regional Anesthesia (UGRA)

    • Decreases the incidence of block failure
    • Improves upon the false negative rate of nerve stimulation techniques
    • Allows for alternative approaches for nerve blockade
    • May accelerate the learning curve for regional anesthesia
    • Provides an additional layer of safety

    Advantages of UGRA

    • Allows for visualization of nerve location and surrounding anatomic structures
    • Provides real-time imaging of needle advancement and local anesthetic injection
    • Reduces the number of needle insertions
    • Improves block quality, onset time, and success rate

    Limitations of UGRA

    • Adds an additional layer of complexity
    • Needles may be slightly longer for certain blocks (e.g., cervical plexus block: 50 mm, interscalene brachial plexus block: 25-50 mm)

    Needle Lengths for Different Blocks

    • Cervical plexus block: 50 mm
    • Interscalene brachial plexus block: 25-50 mm
    • Infraclavicular brachial plexus block: 100 mm
    • Axillary brachial plexus block: 25-50 mm
    • Thoracic paravertebral block: 90 mm
    • Lumbar paravertebral block: 100 mm
    • Lumbar plexus block: 100 mm
    • Sciatic block (posterior approach): 100 mm
    • Sciatic block (anterior approach): 150 mm
    • Femoral block: 50 mm
    • Popliteal block (posterior approach): 50 mm
    • Popliteal block (lateral approach): 100 mm

    Single-Injection vs. Continuous Infusion

    • Catheter benefits: prolonged analgesia, improved ability to participate in rehabilitation, and improved patient satisfaction

    Block Room

    • Short axis: cross-sectional view, structures at a right angle to the probe
    • Long axis: longitudinal view, structures and probe aligned
    • In-plane: visualization of entire needle, including tip
    • Out-of-plane: needle directed at the target in a perpendicular fashion, image may not represent the tip of the needle

    Probe Orientation

    • Terminology: sagittal plane, transverse plane, frontal plane, oblique plane
    • Midsagittal plane and parasagittal plane are types of sagittal planes

    Needle Guidance Principles

    • 3 probe maneuvers: alignment, rotation, and tilt
    • 2 needle maneuvers: advance or withdraw, change in angle of approach

    Practice and Clinical Application

    • Evaluate patients for regional anesthesia
    • Match the appropriate mode of pain control with the surgery
    • Consider preoperative, intraoperative, or postoperative block
    • Follow patients until sensory and motor function return

    Keys to Success

    • Anesthesia team
    • Preoperative management
    • Block selection
    • Proficiency of clinician
    • Knowledge of equipment
    • Local anesthetic solution

    Acronym for Success: SCANNING

    • S: Supplies
    • C: Comfortable positioning
    • A: Ambiance
    • N: Name and procedure
    • N: Nominate a transducer
    • I: Infection control
    • N: Note lateral/medial side on screen
    • G: Gain and depth adjustments

    Local Anesthetics

    • Sensory vs. motor

    Cryoneurolysis

    • Performed in OR, IR, or procedure room
    • Sedation not necessarily required
    • Similar in technique to ultrasound-guided peripheral nerve blockade
    • Can be used to treat acute pain

    Course Objectives

    • Describe essential principles of ultrasound in regional anesthesia
    • Demonstrate foundational knowledge requisite to be proficient in sonoanatomy
    • Apply imaging techniques and transducer maneuvers that improve ultrasound peripheral nerve image

    The Challenge

    • Embracing a multimodal approach to pain management
    • Treating postsurgical pain aggressively
    • Reducing reliance on opioids to minimize undesired opioid-related adverse effects
    • Integrating non-opioid related therapies
    • Comparing systemic vs local interventions to treat pain at its source

    Clinical Goals

    • Aggressive treatment of postsurgical pain
    • Reduced opioid use to minimize adverse effects
    • Integration of non-opioid related therapies
    • Comparing systemic vs local interventions for pain management

    ASA Multimodal Guidelines

    • Utilize multimodal pain management whenever possible
    • Consider therapeutic options like central regional opioids, systemic opioid PCA, and peripheral regional techniques
    • Consider risks and benefits for individual patients
    • Recommend around-the-clock regimens of COXIBs, NSAIDs, or acetaminophen

    Regional Anesthesia Defined

    • Regional anesthesia involves injecting local anesthetics around nerves or nerve groups
    • This results in temporary blockade of nerve impulse conduction, causing analgesia and loss of sensory and motor function

    Multimodal Pain Management Rationale

    • Adopt a multimodal approach to pain management
    • Consider various therapeutic options for individual patients
    • Follow established guidelines for acute pain management

    Regional Anesthesia Needles

    • Cervical plexus block: 50 mm (2 in)
    • Interscalene brachial plexus block: 25 mm (1 in) to 50 mm (2 in)
    • Infraclavicular brachial plexus block: 100 mm (4 in)
    • Axillary brachial plexus block: 25 mm (1 in) to 50 mm (2 in)
    • Thoracic paravertebral block: 90 mm (3.5-4 in)
    • Lumbar paravertebral block: 100 mm (4 in)
    • Sciatic block (posterior approach): 100 mm (4 in)
    • Sciatic block (anterior approach): 150 mm (6 in)
    • Femoral block: 50 mm (2 in)
    • Popliteal block (posterior approach): 50 mm (2 in)
    • Popliteal block (lateral approach): 100 mm (4 in)

    Single-Injection vs. Continuous Infusion

    • Catheter benefits include prolonged analgesia, improved rehabilitation participation, and improved patient satisfaction

    Block Room

    • Ensure proper equipment and medication availability
    • Monitor patients who receive regional anesthesia until sensory and motor function return

    Keys to Success

    • Anesthesia team and technique
    • Preoperative management and patient selection
    • Patient education and surgeon cooperation
    • Intraoperative management
    • Postoperative management
    • Proficiency of clinician and knowledge of equipment
    • Local anesthetic solution and infection control

    Acronym for Success: SCANNING

    • Supplies
    • Comfortable positioning
    • Ambiance
    • Name and procedure
    • Nominate a transducer
    • Infection control
    • Note lateral/medial side on screen
    • Gain and depth adjustments

    Local Anesthetics

    • Sensory vs. motor blockade
    • Continuous interscalene block vs. single-injection interscalene block vs. local infiltration
    • Comparing pain relief and side-effect profiles

    Programmed Intermittent Bolus

    • Provides optimal delivery of local anesthetics through peripheral nerve catheters
    • Improves analgesia, reduces VAS scores, and minimizes rescue opioid use
    • Recognizes variable patterns of efficacy depending on anatomic location

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    Description

    Review the anatomy of pain, including the somatosensory system, peripheral nervous system, spinal cord, and brain. Learn about afferent neurons, ascending and descending pathways, and more.

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