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Questions and Answers
Which type of neurons transmit pain signals from the periphery to the spinal cord?
Which type of neurons transmit pain signals from the periphery to the spinal cord?
What is the primary function of the periaqueductal gray matter?
What is the primary function of the periaqueductal gray matter?
What is the term for the perception of an ordinarily non-noxious stimulus as pain?
What is the term for the perception of an ordinarily non-noxious stimulus as pain?
What is the term for the absence of all sensation?
What is the term for the absence of all sensation?
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Which part of the brain receives fibers from third-order neurons?
Which part of the brain receives fibers from third-order neurons?
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What is the term for pain in the distribution of a nerve or a group of nerves?
What is the term for pain in the distribution of a nerve or a group of nerves?
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What is the term for an abnormal sensation perceived without an apparent stimulus?
What is the term for an abnormal sensation perceived without an apparent stimulus?
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What is the term for the presence of hyperesthesia, allodynia, and hyperalgesia?
What is the term for the presence of hyperesthesia, allodynia, and hyperalgesia?
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What is the primary function of neutrophils in response to invading microbes?
What is the primary function of neutrophils in response to invading microbes?
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What is the primary cause of pain in patients who experience psychogenic pain?
What is the primary cause of pain in patients who experience psychogenic pain?
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What is somatization disorder characterized by?
What is somatization disorder characterized by?
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What percentage of children and adolescents are affected by chronic pain worldwide?
What percentage of children and adolescents are affected by chronic pain worldwide?
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What type of pain is often made worse by touch, movement, emotions, and temperature changes?
What type of pain is often made worse by touch, movement, emotions, and temperature changes?
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What is the primary characteristic of malingering?
What is the primary characteristic of malingering?
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What is a predictor of the development of chronic postsurgical pain in children?
What is a predictor of the development of chronic postsurgical pain in children?
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What is a characteristic of superficial somatic pain?
What is a characteristic of superficial somatic pain?
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What is the mechanism of central pain?
What is the mechanism of central pain?
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What is the primary difference between inflammatory pain and central pain?
What is the primary difference between inflammatory pain and central pain?
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What is a characteristic of visceral nociceptive pain?
What is a characteristic of visceral nociceptive pain?
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What is a subtype of visceral nociceptive pain?
What is a subtype of visceral nociceptive pain?
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What is the primary characteristic of chronic pain?
What is the primary characteristic of chronic pain?
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What is a common symptom associated with visceral pain?
What is a common symptom associated with visceral pain?
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What is a predictor of the persistence of chronic postsurgical pain in children?
What is a predictor of the persistence of chronic postsurgical pain in children?
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What type of pain is characterized by a defined time period?
What type of pain is characterized by a defined time period?
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Which component of pain refers to the neural response to traumatic or noxious stimuli?
Which component of pain refers to the neural response to traumatic or noxious stimuli?
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What is true about the relationship between nociception and pain?
What is true about the relationship between nociception and pain?
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Where does the process of perceiving pain begin?
Where does the process of perceiving pain begin?
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What is suffering, in the context of pain?
What is suffering, in the context of pain?
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What is the primary focus of most commonly employed assessment strategies for pain?
What is the primary focus of most commonly employed assessment strategies for pain?
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What can trigger pain, according to the perception of pain component?
What can trigger pain, according to the perception of pain component?
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What is the relationship between pain and suffering?
What is the relationship between pain and suffering?
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What is a common manifestation of pain in patients who are non-verbal or unable to describe their pain?
What is a common manifestation of pain in patients who are non-verbal or unable to describe their pain?
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What is a physiologic effect of pain on the cardiovascular system?
What is a physiologic effect of pain on the cardiovascular system?
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What is a consequence of chronic pain on the immune system?
What is a consequence of chronic pain on the immune system?
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What is a long-term impact of chronic pain on the nervous system?
What is a long-term impact of chronic pain on the nervous system?
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What is a gastrointestinal effect of pain?
What is a gastrointestinal effect of pain?
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What is a benefit of multimodal anesthesia?
What is a benefit of multimodal anesthesia?
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What is a hematologic effect of pain?
What is a hematologic effect of pain?
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What is a respiratory effect of pain?
What is a respiratory effect of pain?
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What is an advantage of using ultrasound-guided regional anesthesia techniques?
What is an advantage of using ultrasound-guided regional anesthesia techniques?
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What is a limitation of ultrasound-guided regional anesthesia techniques?
What is a limitation of ultrasound-guided regional anesthesia techniques?
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What is a benefit of using ultrasound-guided regional anesthesia techniques?
What is a benefit of using ultrasound-guided regional anesthesia techniques?
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What is a characteristic of traditional nerve stimulation techniques?
What is a characteristic of traditional nerve stimulation techniques?
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What is an advantage of using ultrasound-guided regional anesthesia techniques over traditional techniques?
What is an advantage of using ultrasound-guided regional anesthesia techniques over traditional techniques?
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What is a potential drawback of using ultrasound-guided regional anesthesia techniques?
What is a potential drawback of using ultrasound-guided regional anesthesia techniques?
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What is a benefit of using ultrasound-guided regional anesthesia techniques in terms of needle advancement?
What is a benefit of using ultrasound-guided regional anesthesia techniques in terms of needle advancement?
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What is an advantage of using ultrasound-guided regional anesthesia techniques in terms of learning curve?
What is an advantage of using ultrasound-guided regional anesthesia techniques in terms of learning curve?
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What is the recommended length of a needle for an interscalene brachial plexus block?
What is the recommended length of a needle for an interscalene brachial plexus block?
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What is the term for the plane that divides the body into left and right halves?
What is the term for the plane that divides the body into left and right halves?
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What is a benefit of continuous infusion catheters in pain management?
What is a benefit of continuous infusion catheters in pain management?
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What is the primary purpose of in-plane needle guidance?
What is the primary purpose of in-plane needle guidance?
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What is the recommended length of a needle for a lumbar plexus block?
What is the recommended length of a needle for a lumbar plexus block?
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What is the benefit of practice in ultrasound-guided regional anesthesia?
What is the benefit of practice in ultrasound-guided regional anesthesia?
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What is the recommended length of a needle for a sciatic block with an anterior approach?
What is the recommended length of a needle for a sciatic block with an anterior approach?
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What is a benefit of single-injection nerve blocks?
What is a benefit of single-injection nerve blocks?
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What is the term for the view created when the structures are at a right angle to the probe?
What is the term for the view created when the structures are at a right angle to the probe?
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What is the purpose of out-of-plane needle guidance?
What is the purpose of out-of-plane needle guidance?
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What is the recommended length of a needle for a popliteal block with a posterior approach?
What is the recommended length of a needle for a popliteal block with a posterior approach?
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What is a benefit of continuous infusion catheters in rehabilitation?
What is a benefit of continuous infusion catheters in rehabilitation?
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What is the term for the plane that divides the body into front and back halves?
What is the term for the plane that divides the body into front and back halves?
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What is the recommended length of a needle for a cervical plexus block?
What is the recommended length of a needle for a cervical plexus block?
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What is the benefit of the 3 probe maneuvers (A, R, T) in ultrasound-guided regional anesthesia?
What is the benefit of the 3 probe maneuvers (A, R, T) in ultrasound-guided regional anesthesia?
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What is the primary focus of clinical application in ultrasound-guided regional anesthesia?
What is the primary focus of clinical application in ultrasound-guided regional anesthesia?
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What is a potential cause of nerve injury following a peripheral nerve block?
What is a potential cause of nerve injury following a peripheral nerve block?
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What is the primary focus of the anesthesia team in the preoperative management phase?
What is the primary focus of the anesthesia team in the preoperative management phase?
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What does the acronym SCANNING stand for in the context of anesthesia?
What does the acronym SCANNING stand for in the context of anesthesia?
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What is the primary reason for following up with patients after a peripheral nerve block?
What is the primary reason for following up with patients after a peripheral nerve block?
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What is a key component of the anesthesia team's technique in regional anesthesia?
What is a key component of the anesthesia team's technique in regional anesthesia?
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What is the primary goal of preoperative management in regional anesthesia?
What is the primary goal of preoperative management in regional anesthesia?
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What is a critical aspect of postoperative management in regional anesthesia?
What is a critical aspect of postoperative management in regional anesthesia?
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What is the primary responsibility of the anesthesia team in regional anesthesia?
What is the primary responsibility of the anesthesia team in regional anesthesia?
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What is a characteristic of cryoneurolysis?
What is a characteristic of cryoneurolysis?
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What is the primary advantage of cryoneurolysis over other treatments?
What is the primary advantage of cryoneurolysis over other treatments?
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What is the purpose of cryoneurolysis?
What is the purpose of cryoneurolysis?
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What is the name of the nerve that was treated with percutaneous cryoneurolysis in a pilot study?
What is the name of the nerve that was treated with percutaneous cryoneurolysis in a pilot study?
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Where is cryoneurolysis typically performed?
Where is cryoneurolysis typically performed?
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What is the level of sedation required for cryoneurolysis?
What is the level of sedation required for cryoneurolysis?
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What is the name of the device used for cryoneurolysis?
What is the name of the device used for cryoneurolysis?
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Who wrote a narrative review on cryoneurolysis and percutaneous peripheral nerve stimulation?
Who wrote a narrative review on cryoneurolysis and percutaneous peripheral nerve stimulation?
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What is the primary goal of incorporating UGRA into clinical practice?
What is the primary goal of incorporating UGRA into clinical practice?
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According to the ASA Multimodal Guidelines, what should be considered after thoughtful consideration of the risks and benefits for the individual patient?
According to the ASA Multimodal Guidelines, what should be considered after thoughtful consideration of the risks and benefits for the individual patient?
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What is the benefit of using ultrasound-guided regional anesthesia techniques in terms of needle advancement?
What is the benefit of using ultrasound-guided regional anesthesia techniques in terms of needle advancement?
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What is the primary focus of the clinical goals outlined in the course objectives?
What is the primary focus of the clinical goals outlined in the course objectives?
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What is the advantage of using ultrasound-guided regional anesthesia techniques over traditional techniques?
What is the advantage of using ultrasound-guided regional anesthesia techniques over traditional techniques?
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What is the primary characteristic of the course objectives outlined in the content?
What is the primary characteristic of the course objectives outlined in the content?
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What is the recommended approach to pain management according to the ASA Multimodal Guidelines?
What is the recommended approach to pain management according to the ASA Multimodal Guidelines?
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What is the benefit of integrating non-opioid related therapies into clinical practice?
What is the benefit of integrating non-opioid related therapies into clinical practice?
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What is the recommended needle length for a cervical plexus block?
What is the recommended needle length for a cervical plexus block?
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What is a benefit of continuous infusion catheters in pain management?
What is a benefit of continuous infusion catheters in pain management?
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What is the primary goal of multimodal pain management?
What is the primary goal of multimodal pain management?
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What is the primary mechanism of regional anesthesia?
What is the primary mechanism of regional anesthesia?
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What is the recommended needle length for a thoracic paravertebral block?
What is the recommended needle length for a thoracic paravertebral block?
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What is the recommended approach to pain management, according to the American Society of Anesthesiologists?
What is the recommended approach to pain management, according to the American Society of Anesthesiologists?
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What is the recommended needle length for a sciatic block using the anterior approach?
What is the recommended needle length for a sciatic block using the anterior approach?
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What is the benefit of using regional anesthesia techniques in pain management?
What is the benefit of using regional anesthesia techniques in pain management?
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What is a benefit of using ultrasound-guided regional anesthesia techniques?
What is a benefit of using ultrasound-guided regional anesthesia techniques?
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What is a characteristic of regional anesthesia?
What is a characteristic of regional anesthesia?
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What is the recommended needle length for a lumbar paravertebral block?
What is the recommended needle length for a lumbar paravertebral block?
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What is the recommended needle length for an axillary brachial plexus block?
What is the recommended needle length for an axillary brachial plexus block?
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What is the recommended approach to pain management in patients at high risk of respiratory depression?
What is the recommended approach to pain management in patients at high risk of respiratory depression?
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What is a benefit of using ultrasound-guided regional anesthesia techniques?
What is a benefit of using ultrasound-guided regional anesthesia techniques?
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What is the recommended needle length for an infraclavicular brachial plexus block?
What is the recommended needle length for an infraclavicular brachial plexus block?
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What is the primary focus of the American Society of Anesthesiologists' guidelines for acute pain management?
What is the primary focus of the American Society of Anesthesiologists' guidelines for acute pain management?
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What is crucial to follow after a patient receives regional anesthesia?
What is crucial to follow after a patient receives regional anesthesia?
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What could be the cause of a nerve injury following a peripheral nerve block?
What could be the cause of a nerve injury following a peripheral nerve block?
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What is essential for success in regional anesthesia?
What is essential for success in regional anesthesia?
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What does the acronym SCANNING stand for in regional anesthesia?
What does the acronym SCANNING stand for in regional anesthesia?
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Why is it essential to monitor patients who receive regional anesthesia?
Why is it essential to monitor patients who receive regional anesthesia?
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What is crucial in the management of patients receiving regional anesthesia?
What is crucial in the management of patients receiving regional anesthesia?
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What is essential for the anesthesia team when performing regional anesthesia?
What is essential for the anesthesia team when performing regional anesthesia?
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Why is continuous monitoring essential after regional anesthesia?
Why is continuous monitoring essential after regional anesthesia?
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What is the primary benefit of programmed intermittent bolus over continuous epidural infusion for labor analgesia?
What is the primary benefit of programmed intermittent bolus over continuous epidural infusion for labor analgesia?
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What is the primary advantage of liposomal bupivacaine infiltration over interscalene nerve block for total shoulder arthroplasty?
What is the primary advantage of liposomal bupivacaine infiltration over interscalene nerve block for total shoulder arthroplasty?
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What is the primary benefit of continuous interscalene block over single-injection interscalene block for major shoulder surgery?
What is the primary benefit of continuous interscalene block over single-injection interscalene block for major shoulder surgery?
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What is the primary advantage of programmed intermittent bolus over continuous infusion for peripheral nerve catheters?
What is the primary advantage of programmed intermittent bolus over continuous infusion for peripheral nerve catheters?
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What is the primary benefit of local infiltration over interscalene nerve block for total shoulder arthroplasty?
What is the primary benefit of local infiltration over interscalene nerve block for total shoulder arthroplasty?
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What is the primary advantage of continuous infusion over programmed intermittent bolus for peripheral nerve catheters?
What is the primary advantage of continuous infusion over programmed intermittent bolus for peripheral nerve catheters?
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What is the primary benefit of liposomal bupivacaine infiltration over continuous interscalene block for total shoulder arthroplasty?
What is the primary benefit of liposomal bupivacaine infiltration over continuous interscalene block for total shoulder arthroplasty?
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What is the primary advantage of programmed intermittent bolus over continuous infusion for labor analgesia?
What is the primary advantage of programmed intermittent bolus over continuous infusion for labor analgesia?
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Study Notes
Anatomy of Pain
- The somatosensory system is composed of peripheral nervous system, spinal cord, and brain.
- Afferent neurons, A-delta and C fibers, transmit pain signals to the spinal cord.
- The spinal cord has ascending and descending pathways that process pain information.
- The somatosensory cortex, thalamus, and brain process pain information.
First-Order Neurons
- First-order neurons transmit pain signals from the periphery to the spinal cord.
Ascending Pathways
- Ascending pathways transmit pain signals from the spinal cord to the brain.
- The periaqueductal gray matter is a key structure in the brain that initiates pain inhibition.
Third-Order Neurons
- Third-order neurons transmit pain signals from the thalamus to the cortex.
Common Pain Terms
- Allodynia: perception of non-noxious stimuli as pain.
- Analgesia: absence of pain perception.
- Anesthesia: absence of all sensation.
- Anesthesia dolorosa: pain in an area that lacks sensation.
- Dysesthesia: unpleasant or abnormal sensation with or without stimuli.
- Hyperalgesia: increased response to noxious stimuli.
- Hyperesthesia: increased response to mild stimuli.
- Hyperapthia: presence of hyperesthesia, allodynia, and hyperalgesia.
- Hypoalgesia: diminished response to noxious stimuli.
- Hypoesthesia: reduced cutaneous sensation.
- Neuralgia: pain in the distribution of a nerve or group of nerves.
- Paresthesia: abnormal sensation perceived without stimuli.
- Radiculopathy: functional abnormality of one or more nerve roots.
Classification of Pain
- Etiology of pain: considering the anticipated tissue damage secondary to a procedure.
- Duration of pain: chronic pain lasts more than 3 months.
Mechanism of Pain
- Nociceptive pain: arises from tissue damage or inflammation.
- Somatic nociceptive pain: superficial (sharp, pricking) or deep (dull, aching).
- Visceral nociceptive pain: arises from internal organs, often poorly localized.
- Neuropathic pain: arises from nerve damage or dysfunction.
- Inflammatory pain: arises from inflammation and tissue damage.
- Psychogenic pain: arises from psychological or emotional factors.
- Central pain: arises from lesions in the brain or spinal cord.
Associated Emotional Disorders
- Somatization disorder: physical symptoms cannot be explained, resulting in distress and impairment.
- Conversion disorder: symptoms suggest a medical condition but are not explainable.
- Hypochondriasis: prolonged fear of having a serious illness.
- Malingering: intentional production of physical or psychological symptoms.
- Substance-related disorders: habitual misuse of prescribed or illicit substances.
Physiologic Effects of Pain
- Cardiovascular: hypertension, tachycardia, increased SVR.
- Respiratory: increased O2 consumption, CO2 production, and minute ventilation.
- GI and urinary: decreased motility, hypersecretion of gastric acid, nausea, vomiting, and constipation.
- Hematologic: increased platelet adhesiveness, reduced fibrinolysis, and hypercoagulability.
- Endocrine: increased catabolic hormones, decreased anabolic hormones, and development of negative nitrogen balance.
- Immune: predisposes to infection.
Long Term Impact of Pain
- Plasticity results in alterations in neuronal structure, interneuronal connections, and neurotransmitters.
- Leads to sensitization and wind-up phenomenon.
Multimodal Anesthesia
- Intervene at multiple points in the pain pathway to reduce pain transmission.
Motor Response
- Disappears after injection of local anesthetic or saline
- PNS does not prevent intravascular, intraneural, or pleural puncture
Ultrasound-Guided Regional Anesthesia (UGRA)
- Decreases the incidence of block failure
- Improves upon the false negative rate of nerve stimulation techniques
- Allows for alternative approaches for nerve blockade
- May accelerate the learning curve for regional anesthesia
- Provides an additional layer of safety
Advantages of UGRA
- Allows for visualization of nerve location and surrounding anatomic structures
- Provides real-time imaging of needle advancement and local anesthetic injection
- Reduces the number of needle insertions
- Improves block quality, onset time, and success rate
Limitations of UGRA
- Adds an additional layer of complexity
- Needles may be slightly longer for certain blocks (e.g., cervical plexus block: 50 mm, interscalene brachial plexus block: 25-50 mm)
Needle Lengths for Different Blocks
- Cervical plexus block: 50 mm
- Interscalene brachial plexus block: 25-50 mm
- Infraclavicular brachial plexus block: 100 mm
- Axillary brachial plexus block: 25-50 mm
- Thoracic paravertebral block: 90 mm
- Lumbar paravertebral block: 100 mm
- Lumbar plexus block: 100 mm
- Sciatic block (posterior approach): 100 mm
- Sciatic block (anterior approach): 150 mm
- Femoral block: 50 mm
- Popliteal block (posterior approach): 50 mm
- Popliteal block (lateral approach): 100 mm
Single-Injection vs. Continuous Infusion
- Catheter benefits: prolonged analgesia, improved ability to participate in rehabilitation, and improved patient satisfaction
Block Room
- Short axis: cross-sectional view, structures at a right angle to the probe
- Long axis: longitudinal view, structures and probe aligned
- In-plane: visualization of entire needle, including tip
- Out-of-plane: needle directed at the target in a perpendicular fashion, image may not represent the tip of the needle
Probe Orientation
- Terminology: sagittal plane, transverse plane, frontal plane, oblique plane
- Midsagittal plane and parasagittal plane are types of sagittal planes
Needle Guidance Principles
- 3 probe maneuvers: alignment, rotation, and tilt
- 2 needle maneuvers: advance or withdraw, change in angle of approach
Practice and Clinical Application
- Evaluate patients for regional anesthesia
- Match the appropriate mode of pain control with the surgery
- Consider preoperative, intraoperative, or postoperative block
- Follow patients until sensory and motor function return
Keys to Success
- Anesthesia team
- Preoperative management
- Block selection
- Proficiency of clinician
- Knowledge of equipment
- Local anesthetic solution
Acronym for Success: SCANNING
- S: Supplies
- C: Comfortable positioning
- A: Ambiance
- N: Name and procedure
- N: Nominate a transducer
- I: Infection control
- N: Note lateral/medial side on screen
- G: Gain and depth adjustments
Local Anesthetics
- Sensory vs. motor
Cryoneurolysis
- Performed in OR, IR, or procedure room
- Sedation not necessarily required
- Similar in technique to ultrasound-guided peripheral nerve blockade
- Can be used to treat acute pain
Course Objectives
- Describe essential principles of ultrasound in regional anesthesia
- Demonstrate foundational knowledge requisite to be proficient in sonoanatomy
- Apply imaging techniques and transducer maneuvers that improve ultrasound peripheral nerve image
The Challenge
- Embracing a multimodal approach to pain management
- Treating postsurgical pain aggressively
- Reducing reliance on opioids to minimize undesired opioid-related adverse effects
- Integrating non-opioid related therapies
- Comparing systemic vs local interventions to treat pain at its source
Clinical Goals
- Aggressive treatment of postsurgical pain
- Reduced opioid use to minimize adverse effects
- Integration of non-opioid related therapies
- Comparing systemic vs local interventions for pain management
ASA Multimodal Guidelines
- Utilize multimodal pain management whenever possible
- Consider therapeutic options like central regional opioids, systemic opioid PCA, and peripheral regional techniques
- Consider risks and benefits for individual patients
- Recommend around-the-clock regimens of COXIBs, NSAIDs, or acetaminophen
Regional Anesthesia Defined
- Regional anesthesia involves injecting local anesthetics around nerves or nerve groups
- This results in temporary blockade of nerve impulse conduction, causing analgesia and loss of sensory and motor function
Multimodal Pain Management Rationale
- Adopt a multimodal approach to pain management
- Consider various therapeutic options for individual patients
- Follow established guidelines for acute pain management
Regional Anesthesia Needles
- Cervical plexus block: 50 mm (2 in)
- Interscalene brachial plexus block: 25 mm (1 in) to 50 mm (2 in)
- Infraclavicular brachial plexus block: 100 mm (4 in)
- Axillary brachial plexus block: 25 mm (1 in) to 50 mm (2 in)
- Thoracic paravertebral block: 90 mm (3.5-4 in)
- Lumbar paravertebral block: 100 mm (4 in)
- Sciatic block (posterior approach): 100 mm (4 in)
- Sciatic block (anterior approach): 150 mm (6 in)
- Femoral block: 50 mm (2 in)
- Popliteal block (posterior approach): 50 mm (2 in)
- Popliteal block (lateral approach): 100 mm (4 in)
Single-Injection vs. Continuous Infusion
- Catheter benefits include prolonged analgesia, improved rehabilitation participation, and improved patient satisfaction
Block Room
- Ensure proper equipment and medication availability
- Monitor patients who receive regional anesthesia until sensory and motor function return
Keys to Success
- Anesthesia team and technique
- Preoperative management and patient selection
- Patient education and surgeon cooperation
- Intraoperative management
- Postoperative management
- Proficiency of clinician and knowledge of equipment
- Local anesthetic solution and infection control
Acronym for Success: SCANNING
- Supplies
- Comfortable positioning
- Ambiance
- Name and procedure
- Nominate a transducer
- Infection control
- Note lateral/medial side on screen
- Gain and depth adjustments
Local Anesthetics
- Sensory vs. motor blockade
- Continuous interscalene block vs. single-injection interscalene block vs. local infiltration
- Comparing pain relief and side-effect profiles
Programmed Intermittent Bolus
- Provides optimal delivery of local anesthetics through peripheral nerve catheters
- Improves analgesia, reduces VAS scores, and minimizes rescue opioid use
- Recognizes variable patterns of efficacy depending on anatomic location
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Description
Review the anatomy of pain, including the somatosensory system, peripheral nervous system, spinal cord, and brain. Learn about afferent neurons, ascending and descending pathways, and more.