Pathophysiology of Hypertension

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Questions and Answers

What is the primary function of the baroreceptor reflex in maintaining blood pressure?

  • To sense changes in blood pressure and regulate it back to a set point (correct)
  • To increase cardiac contractility and heart rate
  • To decrease total peripheral resistance
  • To regulate renal function and influence vascular tone

Which system is responsible for regulating renal function and influencing vascular tone in the long term?

  • Autonomic nervous system
  • Renin-angiotensin-aldosterone system (correct)
  • Baroreceptor reflex
  • Pressure natriuresis

What is the effect of sympathetic nervous system (SNS) activation on heart rate?

  • Variable effect on heart rate
  • Decreased heart rate
  • No effect on heart rate
  • Increased heart rate (correct)

What is the primary cause of primary hypertension?

<p>Unknown or no identifiable cause (B)</p> Signup and view all the answers

What is the effect of the autonomic nervous system on total peripheral resistance (TPR)?

<p>Increases TPR (B)</p> Signup and view all the answers

What is the primary function of the pressure natriuresis system in maintaining blood pressure?

<p>To regulate renal function to stabilize blood volume (B)</p> Signup and view all the answers

What happens to the blood pressure when the blood volume falls?

<p>It decreases (D)</p> Signup and view all the answers

What is the effect of increased pressure in afferent arterioles on glomerular filtration?

<p>It increases (B)</p> Signup and view all the answers

What is the mechanism of action of ACE inhibitors in reducing blood pressure?

<p>Inhibiting the production and effects of angiotensin 2 (B)</p> Signup and view all the answers

What is the side effect of ACE inhibitors in 5-10% of patients?

<p>Chronic dry cough (B)</p> Signup and view all the answers

What is the mechanism of action of Ca2+ channel blockers in reducing blood pressure?

<p>Inhibiting the contraction of blood vessels (D)</p> Signup and view all the answers

What is the effect of activated RAAS on pressure natriuresis?

<p>It decreases (D)</p> Signup and view all the answers

What is the primary function of the renin-angiotensin-aldosterone system (RAAS) in the body?

<p>To control blood pressure and blood volume (C)</p> Signup and view all the answers

Which hormone is released from the adrenal cortex in response to angiotensin II?

<p>Aldosterone (C)</p> Signup and view all the answers

What is the effect of angiotensin II on the sensitivity of the baroreceptor reflex to blood pressure?

<p>Decreases sensitivity (A)</p> Signup and view all the answers

Which part of the nervous system stimulates the release of renin from the juxtaglomerular cells?

<p>Sympathetic nervous system (B)</p> Signup and view all the answers

What is the effect of increased arterial blood pressure on sodium excretion in the kidneys?

<p>Decreases sodium reabsorption (D)</p> Signup and view all the answers

What is the enzyme that converts angiotensin I to angiotensin II?

<p>Angiotensin-converting enzyme (ACE) (C)</p> Signup and view all the answers

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