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Pathophysiology of Hypertension
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Pathophysiology of Hypertension

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Questions and Answers

What is the primary function of the baroreceptor reflex in maintaining blood pressure?

  • To sense changes in blood pressure and regulate it back to a set point (correct)
  • To increase cardiac contractility and heart rate
  • To decrease total peripheral resistance
  • To regulate renal function and influence vascular tone
  • Which system is responsible for regulating renal function and influencing vascular tone in the long term?

  • Autonomic nervous system
  • Renin-angiotensin-aldosterone system (correct)
  • Baroreceptor reflex
  • Pressure natriuresis
  • What is the effect of sympathetic nervous system (SNS) activation on heart rate?

  • Variable effect on heart rate
  • Decreased heart rate
  • No effect on heart rate
  • Increased heart rate (correct)
  • What is the primary cause of primary hypertension?

    <p>Unknown or no identifiable cause</p> Signup and view all the answers

    What is the effect of the autonomic nervous system on total peripheral resistance (TPR)?

    <p>Increases TPR</p> Signup and view all the answers

    What is the primary function of the pressure natriuresis system in maintaining blood pressure?

    <p>To regulate renal function to stabilize blood volume</p> Signup and view all the answers

    What happens to the blood pressure when the blood volume falls?

    <p>It decreases</p> Signup and view all the answers

    What is the effect of increased pressure in afferent arterioles on glomerular filtration?

    <p>It increases</p> Signup and view all the answers

    What is the mechanism of action of ACE inhibitors in reducing blood pressure?

    <p>Inhibiting the production and effects of angiotensin 2</p> Signup and view all the answers

    What is the side effect of ACE inhibitors in 5-10% of patients?

    <p>Chronic dry cough</p> Signup and view all the answers

    What is the mechanism of action of Ca2+ channel blockers in reducing blood pressure?

    <p>Inhibiting the contraction of blood vessels</p> Signup and view all the answers

    What is the effect of activated RAAS on pressure natriuresis?

    <p>It decreases</p> Signup and view all the answers

    What is the primary function of the renin-angiotensin-aldosterone system (RAAS) in the body?

    <p>To control blood pressure and blood volume</p> Signup and view all the answers

    Which hormone is released from the adrenal cortex in response to angiotensin II?

    <p>Aldosterone</p> Signup and view all the answers

    What is the effect of angiotensin II on the sensitivity of the baroreceptor reflex to blood pressure?

    <p>Decreases sensitivity</p> Signup and view all the answers

    Which part of the nervous system stimulates the release of renin from the juxtaglomerular cells?

    <p>Sympathetic nervous system</p> Signup and view all the answers

    What is the effect of increased arterial blood pressure on sodium excretion in the kidneys?

    <p>Decreases sodium reabsorption</p> Signup and view all the answers

    What is the enzyme that converts angiotensin I to angiotensin II?

    <p>Angiotensin-converting enzyme (ACE)</p> Signup and view all the answers

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