Pathology Student Notes: Immune System Diseases

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Questions and Answers

What role do CD4+ T cells play in the graft rejection process?

  • Suppress inflammation
  • Inhibit lymphocyte proliferation
  • Release cytokines that incite an inflammatory reaction (correct)
  • Directly kill graft cells

Which of the following factors is NOT influential in graft survival?

  • Genetic considerations
  • Number of acute rejection episodes
  • Recipient's history of opportunistic infections (correct)
  • Donor’s age

What is a primary method of preventing acute rejection in transplant recipients?

  • Increased allograft immunogenicity
  • Plasmapheresis
  • T-cell activation
  • Steroids to reduce inflammation (correct)

What is a key characteristic of AIDS?

<p>Severe immunosuppression leading to opportunistic infections (B)</p> Signup and view all the answers

Which group is considered at highest risk for HIV transmission?

<p>Homosexual and bisexual men (B)</p> Signup and view all the answers

Flashcards

Glomerulopathy

A condition affecting the glomeruli of the kidney, often characterized by inflammation and damage.

Peritubular capilaritis

Inflammation of the small blood vessels surrounding the kidney tubules.

Graft Rejection

An immune response where the recipient's body rejects the transplanted organ.

HLA Matching

The most effective way to prevent graft rejection, aiming to match the donor and recipient's HLA genes.

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CD8+ Cytotoxic T Cells

A type of T cell that plays a vital role in graft rejection by directly attacking the transplanted organ cells.

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Study Notes

Student Notes - Pathology

  • This document is a set of student notes for pathology, focusing on diseases of the immune system.
  • The notes were compiled by medical students currently studying at various medical colleges in Tamil Nadu and Pondicherry.
  • The notes primarily serve as a revision tool for university examinations.
  • The content is derived from various published medical resources.
  • The document does not intend to be a primary learning material but rather a supplementary aid for revision purposes.
  • Key concepts include diseases of the immune system, including amyloidosis, SLE, graft rejection, AIDS, hypersensitivity reactions and primary immunodeficiency syndromes.
  • Information on various diseases, essays, short notes, short answers and updates are provided, including details on specific diseases like amyloidosis (primary and secondary), systemic lupus erythematosus (SLE), morphology of graft rejection, and HIV/AIDS.
  • The materials mention various aspects, including classification, staining, morphology, and clinical features of specific diseases.
  • Acknowledgements are given to the instructors and team members who contributed to the notes' creation.

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