Pathology Quiz (Lec 1) (set 1)

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Questions and Answers

Which process is tightly regulated and energy-dependent?

  • Swelling of cytoplasm
  • Necrosis
  • Apoptosis (correct)
  • Shrinking of cytoplasm

Which process is characterized by the formation of membrane-bound vesicles?

  • Blebbing of plasma membrane, maintains integrity
  • Swelling & disintegration of organelles
  • Necrosis
  • Apoptosis (correct)

Which process shows a ladder pattern on agarose gel electrophoresis?

  • Apoptosis (correct)
  • Necrosis
  • Non-random degradation of DNA
  • Random digestion of DNA

Which process is characterized by the release of cell contents and an inflammatory response?

<p>Necrosis (B)</p> Signup and view all the answers

Which process occurs at 4°C and is a passive process?

<p>Necrosis (B)</p> Signup and view all the answers

Which of the following is NOT an example of a physiological adaptive response during cell stress?

<p>Increased functional demand (A)</p> Signup and view all the answers

What is the function of heat shock proteins (HSPs) during cell stress?

<p>They protect proteins and assist in refolding (B)</p> Signup and view all the answers

What is the difference between hyperplasia and hypertrophy?

<p>Hyperplasia is an increase in the number of cells, while hypertrophy is an increase in cell size (A)</p> Signup and view all the answers

Which of the following is a target of apoptosis?

<p>All of the above (D)</p> Signup and view all the answers

What triggers necrosis in cells?

<p>All of the above (D)</p> Signup and view all the answers

Which of the following is NOT encompassed by the study of pathology?

<p>Biochemistry (D)</p> Signup and view all the answers

What did R. Virchow propose about disease and cellular changes?

<p>Disease is caused by cellular abnormalities (D)</p> Signup and view all the answers

Which of the following is a potential cause of cell death?

<p>Injury (D)</p> Signup and view all the answers

What are some examples of pathological stimuli that can cause cellular stresses?

<p>All of the above (D)</p> Signup and view all the answers

What is the role of genetic and immune factors in cellular adaptation to environmental stresses?

<p>They determine the ability to adapt (D)</p> Signup and view all the answers

Which of the following is NOT included in the study of pathology?

<p>Genetics (B)</p> Signup and view all the answers

What did R. Virchow propose about disease?

<p>Disease is due to abnormalities in cellular structure and function (D)</p> Signup and view all the answers

Which of the following is a pathological process that may result in abnormal cell growth?

<p>Dysplasia (D)</p> Signup and view all the answers

What can stimulate healing in response to pathological stress?

<p>Physical injury (C)</p> Signup and view all the answers

What can cause cellular stresses according to the text?

<p>Osmotic stress (C)</p> Signup and view all the answers

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Study Notes

Cellular Processes

  • Exocytosis is tightly regulated and energy-dependent.
  • Endocytosis is characterized by the formation of membrane-bound vesicles.

Genetic Analysis

  • DNA fragmentation shows a ladder pattern on agarose gel electrophoresis.

Cellular Stress

  • Necrosis is characterized by the release of cell contents and an inflammatory response.
  • Facilitated diffusion occurs at 4°C and is a passive process.

Cellular Response to Stress

  • Heat shock proteins (HSPs) protect cells against protein denaturation during cell stress.
  • Hypertrophy is NOT an example of a physiological adaptive response during cell stress.
  • Hyperplasia is an increase in cell number, while hypertrophy is an increase in cell size.

Apoptosis

  • Apoptosis targets damaged or unwanted cells for destruction.

Pathology

  • Necrosis is triggered by ischemia, which can cause cell death.
  • Pathology does NOT encompass the study of normal cellular function.
  • R.Virchow proposed that disease arises from cellular changes.
  • Cellular stresses can be caused by pathological stimuli, such as radiation or chemicals.
  • Genetic and immune factors play a role in cellular adaptation to environmental stresses.
  • Cancer is a pathological process that may result in abnormal cell growth.
  • Healing can be stimulated in response to pathological stress through various mechanisms, such as protein synthesis.
  • Cellular stresses can be caused by factors such as hypoxia, radiation, or chemicals.

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