28 Questions
What is the innermost layer of the uterus called?
Endometrium
What is the primary role of the stroma in the endometrium?
Providing structural support
Which hormone primarily drives the proliferative phase of the menstrual cycle?
Estrogen
What is the most common cause of dysfunctional uterine bleeding?
Anovulatory cycles
What is the key risk factor for acute endometritis?
Cesarean section delivery
What is the primary function of the spiral arterioles in the secretory phase of the menstrual cycle?
Maintaining the functional layer
Which of the following is not a common cause of an anovulatory cycle?
Endometrial polyps
What is the primary consequence of an anovulatory cycle?
All of the above
What is the primary function of the basal layer of the endometrium?
Regenerating the functional layer
Which of the following is not a characteristic of the secretory phase of the menstrual cycle?
Increased proliferation of the endometrium
Which symptom is not commonly associated with endometrial carcinoma?
Breast tenderness
What is the most common risk factor for endometrioid subtype carcinoma?
Estrogen-dependent hyperplasia
Which characteristic is specific to serous subtype carcinoma of the endometrium?
Pink, serous material on biopsy
Which stage of endometrial carcinoma involves pelvic lymph node involvement?
Stage IIIB
What is a distinguishing feature of Lynch syndrome in relation to endometrial cancer?
Germline mutation in DNA mismatch repair genes
What is the typical initial diagnostic procedure for endometrial carcinoma?
Endometrial biopsy
Which type of endometrial carcinoma is driven by unopposed estrogen?
Endometrioid subtype
What is the main difference between the two major types of endometrial carcinoma?
Histological classification
In which stage of endometrial carcinoma does the tumor invade the bladder mucosa and/or bowel mucosa?
Stage IVB
What is a common feature of serous subtype carcinoma with regard to prognosis?
Poor prognosis due to aggressive behavior
Which condition may occur after delivery or miscarriage and can lead to acute endometritis?
Retained Products of Conception
What is the classic regimen for treating Retained Products of Conception (RPOC)?
Clindamycin + Gentamycin
Which condition is associated with the growth of endometrial tissue (glands and stroma) outside of the uterus?
Endometriosis
What is the hallmark histological finding in endometrial polyps?
Fibrous stroma
Which condition presents with symptoms like heavy menstrual bleeding and painful menstruation due to endometrial glands/stroma in the myometrium?
Adenomyosis
What is the most common gynecologic cancer, commonly seen in postmenopausal women, with its most common type being the endometrioid subtype?
Endometrial carcinoma
Which medication is a competitive antagonist of breast estrogen receptor and can cause endometrial proliferation, hyperplasia, and polyp formation?
Tamoxifen
What treatment is considered first-line therapy for managing Endometriosis?
Oral contraceptive pills (OCPs)
Test your knowledge on the anatomy and layers of the uterine corpus, including the serosa, myometrium, and endometrium. Learn about the functions of the endometrium layers, glands, and stroma in the menstrual cycle.
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