Pathology of Tumors and Cancers
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Questions and Answers

What is a hamartoma composed of?

  • Disorganized mass of tissue with cell types indigenous to the site of the lesion (correct)
  • Disorganized mass of tissue with cell types not indigenous to the site of the lesion
  • Benign tumor with well-differentiated cells
  • Ectopic focus of abnormal tissue
  • What is the term for malignant tumor of lymphocytes?

  • Lymphoma (correct)
  • Seminoma
  • Melanoma
  • Leukemia
  • What is the term for a benign tumor that resembles mature cells of its tissue of origin?

  • Poorly differentiated neoplasm
  • Anaplastic tumor
  • Well-differentiated neoplasm (correct)
  • Undifferentiated neoplasm
  • What is the term for a malignant tumor that grows and develops from the transformation of a single cell?

    <p>Malignant change in the target cell</p> Signup and view all the answers

    What is the term for a tumor that is composed of primitive cells with little differentiation?

    <p>Undifferentiated or anaplastic tumor</p> Signup and view all the answers

    What is the prognosis of a poorly differentiated malignant tumor compared to a well-differentiated malignant tumor?

    <p>Worse</p> Signup and view all the answers

    What is a common characteristic of cancers that occur in individuals with a genetic predisposition?

    <p>Early age at onset and multiple or bilateral tumors</p> Signup and view all the answers

    Which of the following is a viral exposure that is associated with a specific type of cancer?

    <p>Human papilloma virus (HPV) and cervical cancer</p> Signup and view all the answers

    What is a non-hereditary predisposing condition that may increase the risk of cancer?

    <p>Leukoplakia of mucous membranes</p> Signup and view all the answers

    Which of the following is NOT a characteristic of cancers that occur in persons ≥ 55 years?

    <p>Childhood cancers are more common in this age group</p> Signup and view all the answers

    What is the 'soil' theory related to in the context of cancer?

    <p>Two or more primary relatives with the cancer</p> Signup and view all the answers

    What is the primary difference between a Grade I cancer and a Grade III cancer?

    <p>Microscopic appearance</p> Signup and view all the answers

    What is the classification of a tumor that is 3 cm in diameter and has invaded the chest wall?

    <p>T4</p> Signup and view all the answers

    Which of the following tumor markers is an example of an 'ONCO'FETAL marker?

    <p>AFP</p> Signup and view all the answers

    What is the significance of the 'M' in PSMA?

    <p>Membrane</p> Signup and view all the answers

    What is the classification of a tumor with no lymph node metastasis?

    <p>N0</p> Signup and view all the answers

    What is the term for the first tumor marker discovered?

    <p>Carcinoembryonic antigen</p> Signup and view all the answers

    Which of the following is NOT a type of chemical carcinogen initiators?

    <p>Viral particles</p> Signup and view all the answers

    What is the main function of CD8+ T-Cells in tumor immune surveillance?

    <p>To eliminate tumor cells</p> Signup and view all the answers

    Which of the following viruses is associated with the development of Burkitt Lymphoma?

    <p>EBV</p> Signup and view all the answers

    What is the main effect of promoters on initiated cells?

    <p>They increase cell proliferation</p> Signup and view all the answers

    Which type of radiation is associated with the development of hematopoietic tumors?

    <p>Ionizing radiation</p> Signup and view all the answers

    What is the outcome of H.pylori infection in relation to carcinogenesis?

    <p>It leads to the development of gastric lymphomas</p> Signup and view all the answers

    What is a common characteristic of CEA and AFP?

    <p>They can be elevated in both benign and malignant diseases</p> Signup and view all the answers

    What is the primary advantage of PSA as a marker for prostate carcinoma?

    <p>It is not expressed by any tissue other than prostate</p> Signup and view all the answers

    What is the correlation between low AFP levels and a specific condition?

    <p>Down syndrome</p> Signup and view all the answers

    What is a benign condition that can cause elevated PSA levels?

    <p>Benign prostatic hyperplasia</p> Signup and view all the answers

    What is a common feature of CEA, AFP, and PSA?

    <p>They can be elevated in both benign and malignant diseases</p> Signup and view all the answers

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