Cancer Therapy and Pathology Fundamentals

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Questions and Answers

What type of malignant neoplasm originates from pigment-producing cells?

  • Melanoma (correct)
  • Lymphoma
  • Colorectal carcinoma
  • Leukemia

What is the primary mechanism of action of traditional chemotherapy drugs?

  • Hormone-dependent pathways
  • Activating the immune system
  • Inhibiting DNA replication or repair (correct)
  • Targeting abnormal growth pathways

What is the purpose of testing lung cancer biopsies via PCR for EGFR mutations?

  • To diagnose lung cancer
  • To identify patients eligible for Afatinib treatment (correct)
  • To determine the stage of cancer
  • To monitor treatment response

What is the role of molecular pathology in cancer diagnosis?

<p>To identify specific genetic markers for targeted therapy (D)</p> Signup and view all the answers

What is the goal of immune checkpoint inhibitors in cancer therapy?

<p>To activate the immune system to eradicate tumor cells (A)</p> Signup and view all the answers

What is the significance of HER2+ status in breast cancer?

<p>It predicts response to trastuzumab (D)</p> Signup and view all the answers

What is the term for an abnormal cellular proliferation with loss of normal architecture?

<p>Dysplasia (A)</p> Signup and view all the answers

What type of neoplasm originates from epithelial cells and is malignant?

<p>Carcinoma (D)</p> Signup and view all the answers

What is the term for a benign tumor of surface epithelium that grows outward in finger-like fibrovascular stalks?

<p>Papilloma (A)</p> Signup and view all the answers

What is the process called when there is a defect in the molecular controls that regulate cellular proliferation and/or cell death?

<p>Neoplasia (A)</p> Signup and view all the answers

What is the term for the formation and proliferation of connective tissues and cells?

<p>Desmoplasia (B)</p> Signup and view all the answers

What type of neoplasm is made up of several different differentiated cell/tissue types?

<p>Teratoma (C)</p> Signup and view all the answers

What is the term for a lump or swelling in cancer terminology?

<p>Tumor (B)</p> Signup and view all the answers

Which type of gene is involved in maintaining the integrity of the genome?

<p>DNA repair gene (B)</p> Signup and view all the answers

What is the term for the process of non-lethal genetic damage that can lead to cancer?

<p>Mutation (C)</p> Signup and view all the answers

Which of the following is an example of an oncogene?

<p>Src (A)</p> Signup and view all the answers

What is the term for the characteristics of cancer cells that distinguish them from normal cells?

<p>Hallmarks of cancer (C)</p> Signup and view all the answers

Which of the following is NOT a type of gene that can contribute to the development of cancer?

<p>Housekeeping gene (B)</p> Signup and view all the answers

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