WK 5: Pathology of Inflammation and Healing
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Questions and Answers

What type of necrosis is typically seen in tuberculosis?

  • Liquefactive necrosis
  • Fat necrosis
  • Coagulative necrosis
  • Caseous necrosis (correct)
  • What is the outcome of fibrosis in hollow organs?

  • Dilation
  • Obstruction (correct)
  • Rupture
  • Perforation
  • What type of cells are transformed macrophages that form granulomas?

  • Epithelial cells
  • Epithelioid histiocytes (correct)
  • Fibroblasts
  • Endothelial cells
  • What is the primary driver cell in chronic inflammation?

    <p>Macrophages</p> Signup and view all the answers

    What is a common cause of chronic inflammation that starts as a chronic process?

    <p>Persistent infections with low acute virulence</p> Signup and view all the answers

    What is the term for the formation of small blood vessels during the repair process?

    <p>Angiogenesis</p> Signup and view all the answers

    What is the primary cause of chronic inflammation from the outset?

    <p>Persistent infections</p> Signup and view all the answers

    Which type of cell is responsible for ingesting pathogens and dead tissue in chronic inflammation?

    <p>Macrophages</p> Signup and view all the answers

    What is the characteristic feature of granulomatous inflammation?

    <p>Aggregates of macrophages forming granulomas</p> Signup and view all the answers

    What is the outcome of chronic inflammation if it subsides and the affected area scars?

    <p>Inactive</p> Signup and view all the answers

    What type of inflammation is often caused by low acute virulence microorganisms?

    <p>Chronic inflammation</p> Signup and view all the answers

    What is the characteristic feature of the inflammatory cells in chronic inflammation?

    <p>Predominance of mononuclear white blood cells</p> Signup and view all the answers

    What is the outcome of acute inflammation when vital organs are overwhelmed by exogenous toxins and/or products of inflammation?

    <p>Death due to shock and/or loss of function</p> Signup and view all the answers

    What is the term used to describe the mix of capillary vessels and fibroblasts that grow in when an area of tissue dies?

    <p>Granulation tissue</p> Signup and view all the answers

    What is characteristic of chronic inflammation?

    <p>Lasts for weeks to years</p> Signup and view all the answers

    What is the outcome of acute inflammation when tissue dies locally and then putrefies?

    <p>Gangrene</p> Signup and view all the answers

    What is deposited in the extracellular matrix during the healing process?

    <p>Collagen</p> Signup and view all the answers

    What is an example of a condition where acute inflammation is repeated, leading to chronic inflammation?

    <p>Peptic ulcers</p> Signup and view all the answers

    What is the term for the presence of micro-organisms in or on tissue?

    <p>Infection</p> Signup and view all the answers

    What is the term that describes the response of tissues to injury?

    <p>Inflammation</p> Signup and view all the answers

    What is the result of increased blood vessel permeability in acute inflammation?

    <p>Leakage of fluid, fibrin, and red blood cells</p> Signup and view all the answers

    What is the process by which white blood cells move through injured tissue in acute inflammation?

    <p>Chemotaxis</p> Signup and view all the answers

    What is the term for the process by which white blood cells take up pathogens and dead cells?

    <p>Phagocytosis</p> Signup and view all the answers

    What is the term for the presence of micro-organisms on or in tissue without an immune response?

    <p>Colonization</p> Signup and view all the answers

    What is the duration of acute inflammation?

    <p>Hours or a few days</p> Signup and view all the answers

    What is the fifth principal change described in acute inflammation?

    <p>Loss of function</p> Signup and view all the answers

    What is an example of a physical agent that can cause acute inflammation?

    <p>Ionising radiation</p> Signup and view all the answers

    What is the sequence of events in acute inflammation?

    <p>Dilation of arteries and capillaries, then increased blood flow</p> Signup and view all the answers

    What type of micro-organisms can cause acute inflammation?

    <p>Bacteria, viruses, and parasites</p> Signup and view all the answers

    What is the consequence of chronic inflammation?

    <p>Formation of new blood vessels and fibrous tissue</p> Signup and view all the answers

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