Pathology Lecture 2: Neoplasms of Lymph Nodes

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What is more common in lymph nodes?

Primary neoplasms

Secondary neoplasms (correct)

It depends on the location of lymph nodes

Both are equally common

What is a characteristic of tumor cell deposits in secondary tumors?

They resemble the surrounding lymph node tissue

They are always benign

They are difficult to distinguish from primary lymphoma

They resemble the primary tumor from which they are derived (correct)

What is a possible complication of lymphoma?

Leukemia (correct)

Metastasis to extranodal sites

Infection of the lymph nodes

Thrombosis

What is a characteristic feature of nodal lymphomas?

Loss of nodal architecture Signup and view all the answers

What is the most common pattern of involvement in nodal lymphoma?

Localized affection of a group of lymph nodes Signup and view all the answers

Which of the following types of Hodgkin's lymphoma has an excellent prognosis?

Nodular sclerosing Signup and view all the answers

What is a characteristic of affected lymph nodes in nodal lymphoma?

They are enlarged, firm with homogeneous grayish pink cut section Signup and view all the answers

What is a feature of extranodal lymphoma involving the spleen?

Multiple grayish nodules causing splenomegaly Signup and view all the answers

What is the characteristic feature of Reed-Sternberg cells?

Large cells with amphophilic cytoplasm Signup and view all the answers

Which of the following is a type of non-Hodgkin's lymphoma?

Follicular lymphoma Signup and view all the answers

What is the common site of origin for Hodgkin's lymphoma?

Cervical nodes Signup and view all the answers

What is a characteristic feature of high-grade non-Hodgkin's lymphomas?

Aggressive prognosis Signup and view all the answers

What is the primary characteristic of peripheral blood changes in leukemia?

A large number of neoplastic leucocytes Signup and view all the answers

What is the common age group affected by multiple myeloma?

Adults > 40 years Signup and view all the answers

What is the characteristic microscopic feature of bone marrow in multiple myeloma?

Increased plasma cells (>20%) Signup and view all the answers

What is the primary effect of multiple myeloma on the bones?

Bone destruction Signup and view all the answers

What is the common radiological feature of multiple myeloma?

Multiple osteolytic lesions Signup and view all the answers

What is the common site of multiple myeloma?

Skull, vertebrae, sternum, pelvis, and ribs Signup and view all the answers

What is the characteristic feature of a Lacunar cell?

It has shrunken cytoplasm creating a clear space between the nucleus and the cell wall Signup and view all the answers

What is the criteria for Stage IV of Hodgkin Lymphoma?

Involvement of non-lymphoid organs due to blood spread Signup and view all the answers

What is the term for an increase of the total leucocytic count > 11,000/cmm?

Leukocytosis Signup and view all the answers

What is the definition of Leukemia?

A neoplastic proliferation of white blood cells in bone marrow and/or lymphoid tissue Signup and view all the answers

What is the term for a decrease of the total leucocytic count < 4000/cmm?

Leukopenia Signup and view all the answers

What is the term for a type of fever associated with Hodgkin Lymphoma?

Pel-Ebstein fever Signup and view all the answers