Podcast Beta
Questions and Answers
What is the annual incidence of the disease in the UK?
What is the primary purpose of PET-CT in the initial work-up of the disease?
What is required for a favourable prognosis according to GHSG?
What is the primary reason for considering fertility preservation prior to treatment?
Signup and view all the answers
What is the purpose of performing a biopsy in the initial work-up of the disease?
Signup and view all the answers
Which of the following age groups does not have a peak incidence of the disease?
Signup and view all the answers
Which of the following tests is not required for staging?
Signup and view all the answers
What is the primary difference between the 4 histological subtypes of the disease?
Signup and view all the answers
What is the primary reason for performing an HIV test in the initial work-up?
Signup and view all the answers
Which of the following laboratory results is not required for the initial work-up?
Signup and view all the answers
Study Notes
Epidemiology of Hodgkin Lymphoma
- Annual incidence of Hodgkin Lymphoma in the UK is 2.7 per 100,000 people
- Two incidence peaks occur at ages 20-34 and over 70
Initial Work-Up
- Blood tests: FBC, ESR, U&E, LFT, Bone profile, HIV, Hep B, Hep C
- Biopsy is necessary to determine histological subtype
- 4 histological subtypes of Hodgkin Lymphoma: Nodular sclerosis, Mixed cellularity, Lymphocyte-rich, Lymphocyte-depleted
- No difference in outcomes among histological subtypes
Imaging and Staging
- PET-CT is used for staging and detects bone involvement
- BM biopsy is not required
- Fertility preservation should be considered prior to treatment
Staging
- Early stages: Stage I and II
- Favourable prognosis (GHSG) requires:
- No large mediastinal mass
- Normal ESR
Epidemiology of Hodgkin Lymphoma
- Annual incidence of Hodgkin Lymphoma in the UK is 2.7 per 100,000 people
- Two incidence peaks occur at ages 20-34 and over 70
Initial Work-Up
- Blood tests: FBC, ESR, U&E, LFT, Bone profile, HIV, Hep B, Hep C
- Biopsy is necessary to determine histological subtype
- 4 histological subtypes of Hodgkin Lymphoma: Nodular sclerosis, Mixed cellularity, Lymphocyte-rich, Lymphocyte-depleted
- No difference in outcomes among histological subtypes
Imaging and Staging
- PET-CT is used for staging and detects bone involvement
- BM biopsy is not required
- Fertility preservation should be considered prior to treatment
Staging
- Early stages: Stage I and II
- Favourable prognosis (GHSG) requires:
- No large mediastinal mass
- Normal ESR
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Description
This quiz covers the epidemiology of Hodgkin lymphoma, including incidence rates, initial work-up, biopsy, staging, and treatment considerations.
