Podcast
Questions and Answers
What is the cause of hypersensitivity reaction?
What is the cause of hypersensitivity reaction?
- Inheritance of susceptibility genes
- Imbalance between effector cells & regulatory mechanisms (correct)
- Exaggerated immune response to antigens
- Presence of environmental antigens
Which type of immune diseases does hypersensitivity fall under?
Which type of immune diseases does hypersensitivity fall under?
- Autoimmune (self react)
- Immunodeficiency (under react) (correct)
- Both autoimmune and immunodeficiency
- None of the above
What cells are involved in hypersensitivity reactions?
What cells are involved in hypersensitivity reactions?
- Epithelial cells
- Endothelial cells
- Cells of the immune response (correct)
- Red blood cells
Who does hypersensitivity affect?
Who does hypersensitivity affect?
Which type of hypersensitivity reaction is associated with IgE bound to mast cells and basophils?
Which type of hypersensitivity reaction is associated with IgE bound to mast cells and basophils?
What elicits hypersensitivity reactions?
What elicits hypersensitivity reactions?
What is the characteristic feature of atopic individuals?
What is the characteristic feature of atopic individuals?
Which antibody is stimulated by TH2 and binds to FC receptors on the surface of effector cells?
Which antibody is stimulated by TH2 and binds to FC receptors on the surface of effector cells?
What is the main effect of histamine in hypersensitivity reactions?
What is the main effect of histamine in hypersensitivity reactions?
What is the dominant inflammatory cell in the late phase reaction of hypersensitivity I?
What is the dominant inflammatory cell in the late phase reaction of hypersensitivity I?
Which type of reaction occurs 5-30 minutes after re-exposure to an allergen?
Which type of reaction occurs 5-30 minutes after re-exposure to an allergen?
What is the clinical manifestation of systemic (anaphylactic shock) in sensitized individuals?
What is the clinical manifestation of systemic (anaphylactic shock) in sensitized individuals?
Which effector cells are sensitized by IgE in hypersensitivity I?
Which effector cells are sensitized by IgE in hypersensitivity I?
What is the main effect of prostaglandins in hypersensitivity I?
What is the main effect of prostaglandins in hypersensitivity I?
Which type of cell produces IL-5, which activates eosinophils in the late phase reaction?
Which type of cell produces IL-5, which activates eosinophils in the late phase reaction?
What is the role of leukotrienes in hypersensitivity I reactions?
What is the role of leukotrienes in hypersensitivity I reactions?