Pathology: Acute and Chronic Inflammation Repair
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Pathology: Acute and Chronic Inflammation Repair

This quiz covers the types of repair, including regeneration and replacement of damaged cells, in the context of acute and chronic inflammation in pathology.

Created by
@SharpAustin

Questions and Answers

What is a characteristic of healing by primary intention?

Small scar formation

What type of scar is characterized by excess granulation tissue?

Hypertrophic scar

What is an example of a tissue that can repair by regeneration?

Epidermis

What type of cells are hematopoietic cells an example of?

<p>Labile cells</p> Signup and view all the answers

What is the result of repair by regeneration?

<p>Replacement of damaged cells by new cells of the same kind</p> Signup and view all the answers

What is a characteristic of defective healing?

<p>Fistula formation</p> Signup and view all the answers

What type of cells are nerve cells an example of?

<p>Permanent cells</p> Signup and view all the answers

What is a characteristic of healing by secondary intention?

<p>Excess granulation tissue</p> Signup and view all the answers

What is the process of replacing damaged tissue with new healthy tissue called?

<p>Regeneration</p> Signup and view all the answers

Which of the following cells can regenerate continuously?

<p>Surface epithelium</p> Signup and view all the answers

What is the term for the replacement of damaged cells by connective tissue?

<p>Healing by connective tissue</p> Signup and view all the answers

Which of the following factors can affect repair?

<p>Both A and B</p> Signup and view all the answers

What is the term for the healing of a bone fracture through regeneration?

<p>Healing by regeneration</p> Signup and view all the answers

Which of the following tissues is repaired by connective tissue formation?

<p>Skin dermis</p> Signup and view all the answers

What is the difference between 1ry and 2ry intention healing?

<p>All of the above</p> Signup and view all the answers

Which of the following systems heals through gliosis?

<p>Nervous system</p> Signup and view all the answers

Study Notes

Repair or Healing

  • Replacement of damaged tissue by new healthy tissue
  • Types of repair:
    • Regeneration: replacement of damaged cells by new cells of the same kind
    • Healing by connective tissue: replacement of damaged cells by connective tissue (fibrosis or gliosis)

Classification of Body Cells According to Power of Regeneration

  • Labile cells: continuously dividing cells
    • Examples: surface epithelium, haematopoietic cells, lymphoid cells
  • Stable cells: quiescent cells
    • Examples: parenchymatous cells, mesenchymal cells, nerve cells, muscle cells
  • Permanent cells: non-dividing cells
    • Examples: nerve cells, muscle cells

Factors Affecting Repair

  • Local factors: type of damaged cell, blood supply, infection, foreign body
  • Systemic factors: age, nutritional deficiency, glucocorticoids, diabetes mellitus

Tissues Repaired by Regeneration

  • Skin (epidermis)
  • Liver cells
  • Bone fracture
  • Peripheral nerve

Healing of Skin

  • Epidermis: healing by regeneration
  • Dermis: healing by connective tissue formation

Healing of Nervous System

  • Central nervous system: gliosis
  • Peripheral nervous system: regeneration

Primary and Secondary Intention Healing

  • Primary intention: shorter time, scanty granulation tissue, small scar formation, no wound contraction
  • Secondary intention: longer time, excess granulation tissue, large scar formation, wound contraction

Abnormal Healing

  • Excess healing: keloid, hypertrophic scar
  • Defective healing: ulcer, fistula, sinus
  • Contracture

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