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Questions and Answers
What is a characteristic of healing by primary intention?
What is a characteristic of healing by primary intention?
- Small scar formation (correct)
- Longer time
- Wound contraction
- Excess granulation tissue
What type of scar is characterized by excess granulation tissue?
What type of scar is characterized by excess granulation tissue?
- Ulcer scar
- Contracture scar
- Hypertrophic scar (correct)
- Burns
What is an example of a tissue that can repair by regeneration?
What is an example of a tissue that can repair by regeneration?
- Bone
- Dermis
- Epidermis (correct)
- Central Nervous system
What type of cells are hematopoietic cells an example of?
What type of cells are hematopoietic cells an example of?
What is the result of repair by regeneration?
What is the result of repair by regeneration?
What is a characteristic of defective healing?
What is a characteristic of defective healing?
What type of cells are nerve cells an example of?
What type of cells are nerve cells an example of?
What is a characteristic of healing by secondary intention?
What is a characteristic of healing by secondary intention?
What is the process of replacing damaged tissue with new healthy tissue called?
What is the process of replacing damaged tissue with new healthy tissue called?
Which of the following cells can regenerate continuously?
Which of the following cells can regenerate continuously?
What is the term for the replacement of damaged cells by connective tissue?
What is the term for the replacement of damaged cells by connective tissue?
Which of the following factors can affect repair?
Which of the following factors can affect repair?
What is the term for the healing of a bone fracture through regeneration?
What is the term for the healing of a bone fracture through regeneration?
Which of the following tissues is repaired by connective tissue formation?
Which of the following tissues is repaired by connective tissue formation?
What is the difference between 1ry and 2ry intention healing?
What is the difference between 1ry and 2ry intention healing?
Which of the following systems heals through gliosis?
Which of the following systems heals through gliosis?
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Study Notes
Repair or Healing
- Replacement of damaged tissue by new healthy tissue
- Types of repair:
- Regeneration: replacement of damaged cells by new cells of the same kind
- Healing by connective tissue: replacement of damaged cells by connective tissue (fibrosis or gliosis)
Classification of Body Cells According to Power of Regeneration
- Labile cells: continuously dividing cells
- Examples: surface epithelium, haematopoietic cells, lymphoid cells
- Stable cells: quiescent cells
- Examples: parenchymatous cells, mesenchymal cells, nerve cells, muscle cells
- Permanent cells: non-dividing cells
- Examples: nerve cells, muscle cells
Factors Affecting Repair
- Local factors: type of damaged cell, blood supply, infection, foreign body
- Systemic factors: age, nutritional deficiency, glucocorticoids, diabetes mellitus
Tissues Repaired by Regeneration
- Skin (epidermis)
- Liver cells
- Bone fracture
- Peripheral nerve
Healing of Skin
- Epidermis: healing by regeneration
- Dermis: healing by connective tissue formation
Healing of Nervous System
- Central nervous system: gliosis
- Peripheral nervous system: regeneration
Primary and Secondary Intention Healing
- Primary intention: shorter time, scanty granulation tissue, small scar formation, no wound contraction
- Secondary intention: longer time, excess granulation tissue, large scar formation, wound contraction
Abnormal Healing
- Excess healing: keloid, hypertrophic scar
- Defective healing: ulcer, fistula, sinus
- Contracture
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