16 Questions
What is a characteristic of healing by primary intention?
Small scar formation
What type of scar is characterized by excess granulation tissue?
Hypertrophic scar
What is an example of a tissue that can repair by regeneration?
Epidermis
What type of cells are hematopoietic cells an example of?
Labile cells
What is the result of repair by regeneration?
Replacement of damaged cells by new cells of the same kind
What is a characteristic of defective healing?
Fistula formation
What type of cells are nerve cells an example of?
Permanent cells
What is a characteristic of healing by secondary intention?
Excess granulation tissue
What is the process of replacing damaged tissue with new healthy tissue called?
Regeneration
Which of the following cells can regenerate continuously?
Surface epithelium
What is the term for the replacement of damaged cells by connective tissue?
Healing by connective tissue
Which of the following factors can affect repair?
Both A and B
What is the term for the healing of a bone fracture through regeneration?
Healing by regeneration
Which of the following tissues is repaired by connective tissue formation?
Skin dermis
What is the difference between 1ry and 2ry intention healing?
All of the above
Which of the following systems heals through gliosis?
Nervous system
Study Notes
Repair or Healing
- Replacement of damaged tissue by new healthy tissue
- Types of repair:
- Regeneration: replacement of damaged cells by new cells of the same kind
- Healing by connective tissue: replacement of damaged cells by connective tissue (fibrosis or gliosis)
Classification of Body Cells According to Power of Regeneration
- Labile cells: continuously dividing cells
- Examples: surface epithelium, haematopoietic cells, lymphoid cells
- Stable cells: quiescent cells
- Examples: parenchymatous cells, mesenchymal cells, nerve cells, muscle cells
- Permanent cells: non-dividing cells
- Examples: nerve cells, muscle cells
Factors Affecting Repair
- Local factors: type of damaged cell, blood supply, infection, foreign body
- Systemic factors: age, nutritional deficiency, glucocorticoids, diabetes mellitus
Tissues Repaired by Regeneration
- Skin (epidermis)
- Liver cells
- Bone fracture
- Peripheral nerve
Healing of Skin
- Epidermis: healing by regeneration
- Dermis: healing by connective tissue formation
Healing of Nervous System
- Central nervous system: gliosis
- Peripheral nervous system: regeneration
Primary and Secondary Intention Healing
- Primary intention: shorter time, scanty granulation tissue, small scar formation, no wound contraction
- Secondary intention: longer time, excess granulation tissue, large scar formation, wound contraction
Abnormal Healing
- Excess healing: keloid, hypertrophic scar
- Defective healing: ulcer, fistula, sinus
- Contracture
This quiz covers the types of repair, including regeneration and replacement of damaged cells, in the context of acute and chronic inflammation in pathology.
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