33 Questions
What action should you take before copying or distributing others’ copyright-protected materials?
Check if the materials are in line with the University's Fair Dealing Copyright Guidelines
Which of the following is NOT covered under the University’s Fair Dealing Copyright Guidelines?
Posting content on the open web
What type of changes are included in the outline provided for 'Inflammation'?
Vascular changes
Which of the following is NOT a component of the 'Inflammation Outline' provided?
Pathogenesis of Inflammation
What is required if one intends to post others’ copyright-protected materials on the open web?
Seek permission from the copyright holder
What are the 3 major components of acute inflammation related to vascular and cellular events?
Dilation of small vessels, increased vascular permeability, migration and activation of leukocytes
Which of the following is NOT a factor that can activate endothelial cells as mentioned in the text?
Platelet-deactivating factor
What process involves leukocytes assuming a peripheral position during acute inflammation?
Margination
Which of the following is NOT released by endothelium when activated?
Interleukin: IL-8
What is the main role of leukocytes during acute inflammation?
Adhere to endothelial cells and undergo phagocytosis
Which factor contributes to increased vascular permeability during acute inflammation?
Production of PGI2 and NO by endothelium
What are the three steps involved in phagocytosis during acute inflammation?
Recognition, phagosome formation, lysosome discharge
Which of the following proteins enhances the efficiency of phagocytosis by binding to microbes?
Lectins
Which of the following is NOT a major opsonin that enhances the efficiency of phagocytosis?
Albumin
What is formed when a phagosome fuses with a lysosome during phagocytosis?
Phagolysosome
What can happen if a phagocyte releases granule contents into the extracellular space during phagocytosis?
Damage to normal cells
How does opsonization affect the process of phagocytosis during acute inflammation?
Enhances efficiency by binding to microbes
Which cells primarily produce mediators of inflammation at the site of inflammation?
Tissue macrophages
What is the main product of the conversion of O2 by MPO?
(OCl-)
Which type of inflammation is typically NOT infected by destructive organisms?
Serous inflammation
What is the characteristic feature of fibrinous inflammation?
Presence of fibrin in lining of body cavities
Which condition leads to a localized area of liquefactive necrosis?
Purulent inflammation
What is the main component of pus in purulent inflammation?
Neutrophils
Which type of inflammation results in diffuse permeative infiltration of neutrophils with edema?
Purulent inflammation
In which condition do you observe erosion of the epithelial surface exposing the underlying connective tissue?
Ulcers
What is characteristic of serous inflammation?
Exudation of cell-rich fluid.
Which molecule is involved in transmigration of leukocytes during acute inflammation?
PECAM-1 (CD31)
What is the role of Selectins in acute inflammation?
Promote weak, transient sticking
What is dissolved by fibrinolysis in fibrinous inflammation?
Fibrin deposits.
Which of the following is NOT an endogenous chemotactic factor during acute inflammation?
Bacterial products
What stimulates leukocyte activation in acute inflammation?
Complement system (especially C5a)
What is the consequence of leukocyte activation during acute inflammation?
Phagocytosis of particles
After systemic steroid treatment, what mediators are affected in leukocyte activation during acute inflammation?
Prostaglandins
Test your knowledge on the mechanism of inflammation, focusing on acute inflammation and cellular events such as Rolling Selectins, Integrins, and Transmigration. Explore the key concepts related to inflammation and tissue repair.
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