DENT 291 Basic Pathology: Inflammation and Tissue Repair Quiz
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Questions and Answers

What action should you take before copying or distributing others’ copyright-protected materials?

  • Check if the materials are in line with the University's Fair Dealing Copyright Guidelines (correct)
  • Review the University’s plagiarism policy
  • Post the materials on the open web without any concerns
  • Ask for permission from the copyright holder

Which of the following is NOT covered under the University’s Fair Dealing Copyright Guidelines?

  • Distributing materials within a closed network
  • Using materials for educational activities
  • Copying materials for research purposes
  • Posting content on the open web (correct)

What type of changes are included in the outline provided for 'Inflammation'?

  • Biological changes
  • Chemical changes
  • Structural changes
  • Vascular changes (correct)

Which of the following is NOT a component of the 'Inflammation Outline' provided?

<p>Pathogenesis of Inflammation (B)</p> Signup and view all the answers

What is required if one intends to post others’ copyright-protected materials on the open web?

<p>Seek permission from the copyright holder (A)</p> Signup and view all the answers

What are the 3 major components of acute inflammation related to vascular and cellular events?

<p>Dilation of small vessels, increased vascular permeability, migration and activation of leukocytes (C)</p> Signup and view all the answers

Which of the following is NOT a factor that can activate endothelial cells as mentioned in the text?

<p>Platelet-deactivating factor (D)</p> Signup and view all the answers

What process involves leukocytes assuming a peripheral position during acute inflammation?

<p>Margination (C)</p> Signup and view all the answers

Which of the following is NOT released by endothelium when activated?

<p>Interleukin: IL-8 (A)</p> Signup and view all the answers

What is the main role of leukocytes during acute inflammation?

<p>Adhere to endothelial cells and undergo phagocytosis (D)</p> Signup and view all the answers

Which factor contributes to increased vascular permeability during acute inflammation?

<p>Production of PGI2 and NO by endothelium (D)</p> Signup and view all the answers

What are the three steps involved in phagocytosis during acute inflammation?

<p>Recognition, phagosome formation, lysosome discharge (C)</p> Signup and view all the answers

Which of the following proteins enhances the efficiency of phagocytosis by binding to microbes?

<p>Lectins (A)</p> Signup and view all the answers

Which of the following is NOT a major opsonin that enhances the efficiency of phagocytosis?

<p>Albumin (D)</p> Signup and view all the answers

What is formed when a phagosome fuses with a lysosome during phagocytosis?

<p>Phagolysosome (A)</p> Signup and view all the answers

What can happen if a phagocyte releases granule contents into the extracellular space during phagocytosis?

<p>Damage to normal cells (D)</p> Signup and view all the answers

How does opsonization affect the process of phagocytosis during acute inflammation?

<p>Enhances efficiency by binding to microbes (A)</p> Signup and view all the answers

Which cells primarily produce mediators of inflammation at the site of inflammation?

<p>Tissue macrophages (A)</p> Signup and view all the answers

What is the main product of the conversion of O2 by MPO?

<p>(OCl-) (C)</p> Signup and view all the answers

Which type of inflammation is typically NOT infected by destructive organisms?

<p>Serous inflammation (C)</p> Signup and view all the answers

What is the characteristic feature of fibrinous inflammation?

<p>Presence of fibrin in lining of body cavities (D)</p> Signup and view all the answers

Which condition leads to a localized area of liquefactive necrosis?

<p>Purulent inflammation (D)</p> Signup and view all the answers

What is the main component of pus in purulent inflammation?

<p>Neutrophils (B)</p> Signup and view all the answers

Which type of inflammation results in diffuse permeative infiltration of neutrophils with edema?

<p>Purulent inflammation (B)</p> Signup and view all the answers

In which condition do you observe erosion of the epithelial surface exposing the underlying connective tissue?

<p>Ulcers (C)</p> Signup and view all the answers

What is characteristic of serous inflammation?

<p>Exudation of cell-rich fluid. (A)</p> Signup and view all the answers

Which molecule is involved in transmigration of leukocytes during acute inflammation?

<p>PECAM-1 (CD31) (B)</p> Signup and view all the answers

What is the role of Selectins in acute inflammation?

<p>Promote weak, transient sticking (B)</p> Signup and view all the answers

What is dissolved by fibrinolysis in fibrinous inflammation?

<p>Fibrin deposits. (A)</p> Signup and view all the answers

Which of the following is NOT an endogenous chemotactic factor during acute inflammation?

<p>Bacterial products (C)</p> Signup and view all the answers

What stimulates leukocyte activation in acute inflammation?

<p>Complement system (especially C5a) (D)</p> Signup and view all the answers

What is the consequence of leukocyte activation during acute inflammation?

<p>Phagocytosis of particles (B)</p> Signup and view all the answers

After systemic steroid treatment, what mediators are affected in leukocyte activation during acute inflammation?

<p>Prostaglandins (D)</p> Signup and view all the answers

Flashcards

Copyright material use: Before?

Ensure alignment with the University's Fair Dealing Copyright Guidelines.

Copyright Guidelines: NOT covered?

Posting content on the open web without permission.

'Inflammation' changes covered?

Vascular changes.

'Inflammation Outline': NOT included?

Pathogenesis of Inflammation.

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Copyright material on web: Required?

Seek permission from the copyright holder.

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Acute inflammation: 3 components?

Dilation of small vessels, increased vascular permeability & leukocyte migration/activation.

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Endothelial activation: NOT a factor?

Platelet-deactivating factor.

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Leukocyte positioning process?

Margination.

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Endothelium activation: NOT released?

Interleukin: IL-8.

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Leukocyte's main role?

Adhere to endothelial cells and undergo phagocytosis.

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Vascular permeability during inflammation: Increased by?

Production of PGI2 and NO by endothelium does not INCREASE vascular permeability.

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Phagocytosis: 3 steps?

Recognition, phagosome formation, lysosome discharge.

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Phagocytosis efficiency: Protein?

Lectins.

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Phagocytosis: NOT a major opsonin?

Albumin.

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Phagosome + Lysosome = ?

Phagolysosome.

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Phagocyte granule release: Result?

Damage to normal cells.

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Opsonization effect on Phagocytosis?

Enhances efficiency by binding to microbes.

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Inflammation mediators: Primary cell?

Tissue macrophages.

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MPO converts O2 into?

(OCl-)

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Inflammation type: Typically not infected?

Serous inflammation.

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Fibrinous inflammation characteristic?

Presence of fibrin in lining of body cavities.

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Liquefactive necrosis: Condition?

Purulent inflammation.

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Purulent inflammation: Main component of pus?

Neutrophils.

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Neutrophil infiltration with edema: Inflammation type?

Purulent inflammation.

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Epithelial erosion: Condition?

Ulcers.

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Serous inflammation: characteristic?

Exudation of protein-rich fluid.

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Leukocyte transmigration: Molecule?

PECAM-1 (CD31).

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Selectins role in inflammation?

Promote weak, transient sticking.

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Fibrinous inflammation: Fibrinolysis dissolves?

Fibrin deposits.

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Acute inflammation: NOT an endogenous chemotactic factor?

Bacterial products. (C5a is produced in response to bacterial products).

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Leukocyte Activation: Stimulated by?

Complement system (especially C5a).

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Leukocyte activation consequence?

Phagocytosis of particles.

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Systemic steroid treatment: mediators affected during leukocyte activation?

Prostaglandins.

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