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Pathological Hemostasis and Thrombosis

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Questions and Answers

What is the primary function of a healthy endothelium in preventing thrombosis?

Expressing P-selectin

Preventing platelets from coming into contact with collagen and vWF (correct)

Promoting platelet aggregation

Releasing inflammatory cytokines

What is the main component of a red thrombus?

Fibrin and RBCs (correct)

Fibrin and platelets

Platelets and fibrin

RBCs and leukocytes

What is the result of fibrinolysis in thrombi?

Release of inflammatory cytokines

Accumulation of additional platelets and fibrin

Propagation of the thrombus

Dissolution of the thrombus (correct)

What is the primary cause of death in SARS-Cov2 patients?

Thrombosis Signup and view all the answers

What is the genetic mutation associated with resistance to the anticoagulant action of activated protein C?

Point mutation in factor V Signup and view all the answers

What is the primary requirement for Inappropriate/Pathological Intravasal Activation of Hemostasis to occur?

A live endothelium Signup and view all the answers

What is the main cause of Virchow's Triad?

Endothelial injury Signup and view all the answers

What is the function of Plasminogen activators in the context of hemostasis?

To cause the fibrinolytic activity Signup and view all the answers

What is the effect of Endothelial-derived relaxing factor (EDRF) on blood vessels?

Vasodilation Signup and view all the answers

What is the main consequence of endothelial injury in the context of hemostasis?

Thrombus formation Signup and view all the answers