Pathological Fracture Laboratory Work-up Quiz

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which criterion is part of the diagnostic criteria for multiple myeloma?

  • Elevated white blood cell count
  • Presence of M component in blood (correct)
  • Low platelet count
  • High red blood cell count

What diagnostic tests are recommended for evaluating plasma dyscrasia?

  • Blood film, chemistry including calcium and creatinine, and bone marrow aspirate & biopsy
  • Serum protein electrophoresis, quantification of immunoglobulins, and CT or MRI (correct)
  • Complete blood count, urine culture, and liver function tests
  • CT or MRI, blood culture, and urine dipstick test

What is the threshold for serum calcium elevation in the CRAB criteria for multiple myeloma?

  • Serum calcium >11.5 mg/dL (correct)
  • Serum calcium >13.5 mg/dL
  • Serum calcium >10.5 mg/dL
  • Serum calcium >12.5 mg/dL

What impacts the aggressiveness of multiple myeloma?

<p>Several variables that impact disease biology (B)</p> Signup and view all the answers

What is the primary cause of pruritus in the context of the given text?

<p>Increased histamine release from basophils and mast cells (A)</p> Signup and view all the answers

Which mutation is typically associated with Polycythemia Vera?

<p>JAK2V617F (A)</p> Signup and view all the answers

What characterizes bone marrow biopsy in Polycythemia Vera?

<p>Hypercellularity for age with trilineage growth (A)</p> Signup and view all the answers

What is the main stimulus for hyperproliferation of fibroblasts in myelofibrosis?

<p>PDGF, EGF, TGF-β released from myeloid cells (A)</p> Signup and view all the answers

What is the predominant phenotypic expression of the myeloproliferative clone in Polycythemia Vera (PV)?

<p>Erythroid proliferation (B)</p> Signup and view all the answers

Which clinical feature is present in approximately 40% of patients at the time of diagnosis of Polycythemia Vera (PV)?

<p>Splenomegaly (C)</p> Signup and view all the answers

What is a common complication of Polycythemia Vera (PV) that can lead to impaired oxygen delivery?

<p>Erythrocytosis and hyperviscosity (D)</p> Signup and view all the answers

What may be observed on examination of the eye grounds in patients with Polycythemia Vera (PV)?

<p>Engorged, tortuous, and irregular vessels (D)</p> Signup and view all the answers

Flashcards are hidden until you start studying

More Like This

Pathological Anatomy Module 2 Quiz
32 questions
Understanding Bone Fractures
34 questions
Fractures and their Classifications
37 questions

Fractures and their Classifications

GroundbreakingAphorism7812 avatar
GroundbreakingAphorism7812
Use Quizgecko on...
Browser
Browser