Pathogenic Gram Positive Cocci & Bacilli: Staphylococcus Structure & Physiology

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Clostridium tetani is a small, motile, obligate anaerobe that produces a terminal endospore, giving the cell a distinctive “lollipop” appearance; it is ubiquitous in soil, dust and GIT of animals and humans. Tetanus toxin is a potent ______ IV.

neurotoxin

Listeria monocytogenes is a non-spore forming coccobacillus found in soil, water, mammals, birds, fish, insects. It enters the body in contaminated food and drink. Binds to surface macrophage and triggers its own phagocytosis – after forming a hole in the phagosome membrane it grows and reproduce inside the cytosol – then tunnels to the cell surface where it forms pseudopods – a neighboring macrophage phagocytizes the pseudopod then cycle begins again. It is a ______ bacterium.

coccobacillus

Corynebacterium is a genus of high G(+)C, pleomorphic, no endospore-forming bacteria that are ubiquitous on plants and in animals – humans; they divide by snapping division. Corynebacterium diphtheria is transmitted via respiratory droplets. Disease caused by Corynebacterium diphtheria is ______.

DIPHTHERIA

Mycobacterium have cell walls containing an abundance of waxy lipid – ______.

MYCOLIC ACID

Propionibacterium acnes – living in sebaceous gland of the skin, causes ______.

acne

Nocardia is a fast, common inhabitant of soils rich in organic matter. Diseases caused by Nocardia include ______.

Pneumonia, Mycetoma

This quiz covers the structure and physiology of Staphylococcus bacteria, including their facultative anaerobic nature, spherical cell arrangement, salt tolerance, and pathogenicity factors. Topics include protein A interference with the immune response and common pathogens such as S. aureus and S. epidermidis.

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