Pasteurella Overview
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Questions and Answers

What is a key characteristic of Pasteurella multocida toxin?

  • It has a molecular weight of 20,000—30,000.
  • It is a non-lethal toxin that does not cause necrosis.
  • It is primarily cell-associated and released upon bacterial death. (correct)
  • It is heat-stable and not immunogenic.
  • In what manner may Pasteurella multocida enter the body?

  • Only through inhalation.
  • Through ingestion, inhalation, and contact with fomites. (correct)
  • Only through direct contact.
  • Exclusively via wounds.
  • Which of the following best describes the pathogenicity of Pasteurella multocida?

  • It is only a primary pathogen in swine.
  • It is rarely involved in pneumonia of cattle.
  • It is frequently a secondary invader, particularly in pneumonia. (correct)
  • It is never associated with respiratory diseases.
  • What condition is characterized by atrophy of the turbinate bones and distortion of the nasal septum in swine?

    <p>Atrophic rhinitis</p> Signup and view all the answers

    What influences the virulence of Pasteurella multocida?

    <p>Environmental stresses on the host.</p> Signup and view all the answers

    What type of disease does serotype B:2 primarily cause?

    <p>Hemorrhagic septicemia in many regions</p> Signup and view all the answers

    What is the new name proposed for P. haemolytica, biotype T?

    <p>Bibersteinia trehalosi</p> Signup and view all the answers

    What type of toxin do Pasteurella trehalosi and Mannheimia haemolytica produce?

    <p>Leukotoxin</p> Signup and view all the answers

    Which characteristic differentiates the biotypes of P. haemolytica?

    <p>Biochemical activity</p> Signup and view all the answers

    Which of the following properties does the cytotoxin produced by M. haemolytica have?

    <p>It is soluble and immunogenic</p> Signup and view all the answers

    Which of the following diseases is associated with Mannheimia haemolytica?

    <p>Pneumonic pasteurellosis in cattle</p> Signup and view all the answers

    What type of media is required for the optimal growth of Pasteurella species?

    <p>Media containing serum or blood</p> Signup and view all the answers

    What effect does the leukotoxin produced by Pasteurella trehalosi have on ruminants?

    <p>It kills alveolar macrophages</p> Signup and view all the answers

    What is a common characteristic of the colonies produced by Pasteurella species on culture media?

    <p>They are surrounded by a zone of beta-hemolysis</p> Signup and view all the answers

    Study Notes

    Pasteurella

    • Pasteurella and Mannheimia organisms are found worldwide.
    • Pasteurella multocida is a common commensal in the respiratory and digestive tracts of animals.
    • Pasteurella multocida can cause infection through direct or indirect contact, inhalation, ingestion, and wounds.
    • Pasteurella multocida is a secondary invader in many lung infections.
    • Pasteurella multocida is a primary cause of disease in fowl cholera and hemorrhagic septicemia.
    • Pasteurella multocida is also a secondary cause of pneumonia in cattle, swine, sheep, goats, and other species.
    • Pasteurella multocida toxin is cell-associated, heat-labile, and lethal to mice.
    • Pasteurella multocida is the causative agent of atrophic rhinitis in swine.
    • Pasteurella multocida causes a chronic infection in swine, leading to nasal inflammation, bone atrophy, and facial distortion.
    • Pasteurella multocida can be classified into serotypes based on differences in their polysaccharide capsules.
    • Pasteurella multocida Type A is common in fowl cholera, pneumonia, and many other infections in various animals.
    • Pasteurella multocida Type B is a common cause of hemorrhagic septicemia in Asia, the Middle East, and southern Europe.
    • Pasteurella multocida Type D is isolated from pneumonia and atrophic rhinitis in swine.
    • Pasteurella multocida has been linked to "snuffles" in rabbits, mastitis in cattle and sheep, and infections such as encephalitis, meningitis, and abortion.
    • Pasteurella multocida, like many gram-negative bacteria, uses endotoxins in pathogenesis.
    • Pasteurella trehalosi (formerly Pasteurella haemolytica, biotype T) is a distinct biotype, differing in pathogenicity, antigenicity, and biochemistry.
    • Mannheimia haemolytica (formerly Pasteurella haemolytica, biotype A) produces a soluble cytotoxin that kills lung cells, making it a significant pathogen.
    • Mannheimia haemolytica is a primary or secondary cause of pneumonia in cattle, goats, and sheep.
    • Mannheimia haemolytica can also cause mastitis in ewes and septicemia in nursing lambs.
    • Pasteurella trehalosi causes septicemia in feeder lambs.
    • Pasteurella anatipestifer has been renamed Riemerella anatipestifer.

    Laboratory Diagnosis

    • Pasteurella species require media enriched with serum or blood for optimal growth.
    • Pasteurella colonies are typically round, grayish, and may display beta-hemolysis.
    • Pasteurella species are gram-negative rods or coccobacilli and are non-motile.
    • Pasteurella multocida is indole-positive and oxidase-positive.
    • Mannheimia haemolytica is beta-hemolytic and indole-negative.
    • Mannheimia haemolytica can grow on MacConkey agar.
    • Mice and rabbits are generally susceptible to most Pasteurella strains.
    • Definitive diagnosis of Pasteurella species is based on isolation and identification through biochemical tests.
    • Pasteurella species are typically isolated from the site of infection.
    • Pasteurella species survive well in transport media and in refrigerated and frozen tissues.

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    Description

    Explore the fascinating world of Pasteurella, particularly focusing on Pasteurella multocida. This quiz covers its role in animal health, common infections it causes, and classifications within its species. Test your knowledge on how this organism affects various livestock and pets.

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