Passively Acquired Immunity Quiz

Passively acquired immunity means 'borrowed' immunity from another source and lasts for a short time. It provides temporary protection against infection and clearance of toxins.

The disadvantages include hypersensitivity in response to the foreign protein, and the protection is lost as acquired antibodies are utilized by combination with antigen or are catabolized in the normal way. These drawbacks can be overcome by replacing polyclonal antibody preparations by human monoclonal antibodies or combinations of such antibodies.

A passively administered antibody is an antibody isolated from the plasma of an individual having a high antibody titer to the pathogen or a hyperimmunized animal. It is used in anti-venoms and in prophylaxis for certain viral infections including cytomegalovirus (CMV) and rabies.

<p>The drawbacks can be overcome by replacing polyclonal antibody preparations by human monoclonal antibodies or combinations of such antibodies.</p> Signup and view all the answers

<p>The major immunoglobulin in milk is secretory IgA (SIgA) and it remains in the intestine to protect the mucosal surfaces.</p> Signup and view all the answers

<p>The fetus is protected by maternally acquired IgG antibodies through placental transfer.</p> Signup and view all the answers

<p>Intravenous immunoglobulin (IVIg) is a preparation of IgG obtained by large-scale fractionation of plasma pooled from thousands of healthy blood donors. It is given to individuals with immunodeficiencies associated with reduced or absent circulating antibody and used in the treatment of infection-associated conditions.</p> Signup and view all the answers

<p>The neonate is protected by maternally derived IgG antibodies through intestinal absorption of colostral immunoglobulins.</p> Signup and view all the answers