Passive Diffusion in Pharmacology
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Questions and Answers

What characterizes passive diffusion of drug molecules?

  • It is a saturable process.
  • It occurs from higher to lower concentration. (correct)
  • It is mediated by specific carriers.
  • It requires energy in the form of ATP.

Aqueous diffusion is dependent on lipid solubility.

False (B)

What is the maximum pore diameter of aquaporins involved in aqueous diffusion?

0.4 nm

Passive diffusion is a process that ______ energy to move drug molecules.

<p>does not require</p> Signup and view all the answers

Match the following terms with their descriptions:

<p>Passive Diffusion = Concentration gradient dependent process, no energy required Aqueous Diffusion = Filtration of water-soluble drugs through aquaporins Hydrophilic Drugs = Drugs that are lipid insoluble Lipophilic Drugs = Drugs that can easily cross lipid membranes</p> Signup and view all the answers

Flashcards

Passive diffusion

Drug movement from high to low concentration, no energy needed, and no specific carrier.

Aqueous diffusion

Water-soluble drugs move through tiny channels, dictated by size and blood flow, not by drug's properties.

Concentration gradient

Difference in drug concentration driving passive diffusion.

Drug transport by Aqueous diffusion

Drug movement through water channels, governed by blood flow and molecular weight.

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Passive diffusion requirement

No energy, concentration difference

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