Particle Size Distribution & Analysis Introduction

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What is the surface diameter of a particle?

The diameter of a sphere with the same surface area as the particle

Which type of diameter is used when analyzing powders used for suspension?

Sedimentation diameter

In microscopy, what is the optical size range for particle size analysis?

0.5-100 µm

What method is used to determine the particle size range through electronic means?

Electronic determination of PS (Coulter counter)

What is the main purpose for using stoke's diameter in particle size analysis?

Measuring sedimentation rate

When analyzing powders for pharmacological action after dissolution and absorption, which diameter is typically used?

Volume diameter

What is the sedimentation diameter used to describe in particle size analysis?

Sedimentation rate of a particle

In microscopy for particle size analysis, how is the sample prepared?

Prepared as a slurry in a liquid dispersion medium

What determines the type of expressed diameter used in particle size analysis?

The method used to determine the diameter

What does volume diameter represent in particle size analysis?

The size of a sphere with the same volume as a particle

Learn about the importance of characterizing physical and chemical properties of drug molecules during preformulation and product development stages, with a focus on designing an optimal drug delivery system. Understand the definition of particle size and how it impacts various properties of drugs.

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