Parkinson's Medications

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Questions and Answers

What is a potential adverse effect associated with dopamine agonists?

  • Sudden sleep events (correct)
  • Improved concentration
  • Decreased appetite
  • Hypertension

Which statement by a patient taking carbidopa-levodopa indicates a need for further education regarding the medication?

  • "Consuming high-protein foods could impact how the medication works."
  • "I should take the drug with food to improve absorption." (correct)
  • "It may take several weeks to see the full benefits of the medication."
  • "I should take it with food to avoid stomach upset."

A patient has been taking levodopa for 2 weeks and reports no improvement in symptoms. What is the most appropriate response by the healthcare provider?

  • "It can take several months to see a noticeable improvement with this medication." (correct)
  • "You should increase your dose to see if that helps."
  • "The medication is likely not effective for you."
  • "We should switch you to a different medication immediately."

A patient on levodopa is experiencing dystonic movements and nausea. Which medication might be considered as a replacement?

<p>Bromocriptine (Parlodel) (B)</p> Signup and view all the answers

What dietary advice is most important for a patient prescribed selegiline HCl (Eldepryl)?

<p>Avoid foods high in tyramine (C)</p> Signup and view all the answers

Which of the following is an important consideration when educating a patient about apomorphine?

<p>Apomorphine is administered using a multidose injector pen. (A)</p> Signup and view all the answers

Which statement by a student nurse about levodopa/carbidopa indicates that they need further education?

<p>&quot;The combination of these medications results in fewer dyskinesias and decreased psychosis.&quot; (A)</p> Signup and view all the answers

A patient reports no improvement in their Parkinson's symptoms after several months of taking Sinemet (carbidopa/levodopa). What is the most appropriate action for the provider to take?

<p>Re-evaluate the patient's diagnosis. (C)</p> Signup and view all the answers

A patient on Sinemet (carbidopa/levodopa) reports experiencing random 'off' episodes. What is the most appropriate suggestion for the nurse to make?

<p>Suggest adding a COMT inhibitor, such as entacapone. (A)</p> Signup and view all the answers

Which non-pharmacological recommendations are most appropriate for a nurse to offer to a patient in the early stages of Parkinson's disease?

<p>Encouraging exercise, nutritional counseling, and joining support groups (A)</p> Signup and view all the answers

A patient taking rasagiline (Azilect) is found to have elevated blood pressure. Which medication currently prescribed should the nurse consider holding?

<p>Ciprofloxacin (B)</p> Signup and view all the answers

A patient taking entacapone reports experiencing dizziness. What clinical implication does this suggest?

<p>A reduction in the medication dosage may be necessary. (C)</p> Signup and view all the answers

When serving a meal to a patient who is taking an MAO-B inhibitor, which food should be removed from their tray to prevent potential adverse effects?

<p>Cheese (B)</p> Signup and view all the answers

Which of the following instructions should the nurse provide to a patient who is beginning carbidopa-levodopa therapy?

<p>Rise slowly from a bed or chair to reduce the risk of dizziness and falls. (C)</p> Signup and view all the answers

A patient presents with symptoms of shuffling gait and resting tremors. Which medication is the most likely initial treatment?

<p>Carbidopa-levodopa (Sinemet) (C)</p> Signup and view all the answers

Why is carbidopa commonly administered in combination with levodopa for patients with Parkinson's disease?

<p>To reduce peripheral side effects by inhibiting dopa decarboxylase in the periphery (A)</p> Signup and view all the answers

Which side effect is more commonly associated with pramipexole compared to other dopamine agonists?

<p>Sleep attacks (A)</p> Signup and view all the answers

A patient Parkinson patient on Sinemet (carbidopa/levodopa) begins to exhibit tics. What does this clinical development indicate?

<p>The patient may need a decreased dose of Sinemet. (D)</p> Signup and view all the answers

Which potential side effect of levodopa would support a nursing diagnosis of 'Risk for Injury'?

<p>Orthostatic hypotension (D)</p> Signup and view all the answers

A patient taking Sinemet (carbidopa/levodopa) reports experiencing nausea and vomiting. What advice should the nurse provide?

<p>Take a lower dose with a low-protein snack (D)</p> Signup and view all the answers

Flashcards

Dopamine agonists adverse effect

May cause sudden sleep events.

Carbidopa-levodopa teaching

Taking carbidopa-levodopa with food increases absorption.

Levodopa onset

It may take several months for levodopa to show effects.

Apomorphine usage

Combining apomorphine with Tigan can alleviate nausea.

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Levodopa/carbidopa education

Carbidopa reduces side effects, and levodopa crosses the blood-brain barrier.

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No improvement after Sinemet months

Re-evaluate the diagnosis.

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"Off" Episodes on Sinemet

Add a COMT inhibitor like entacapone.

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Non-drug Parkinson's care

Recommend exercise, nutritional counseling, and support groups.

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Rasagiline and high BP

Consider holding ciprofloxacin.

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Entacapone and dizziness

Reduce the medication reduction.

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MAO-B inhibitor diet restrictions

Remove cheese from the meal tray.

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Carbidopa-levodopa education

Rise slowly from bed or a chair to avoid dizziness and falls

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Shuffling gait and resting tremors

Carbidopa-levodopa (Sinemet).

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Why combine carbidopa with levodopa?

To reduce peripheral side effects by inhibiting dopa decarboxylase in the periphery.

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Pramipexole side effect

Sleep attacks.

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Parkinson's patient on Sinemet and develops tics

May need a lower dose of Sinemet.

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Levodopa side effect leading to "Risk for injury"

Orthostatic hypotension.

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Sinemet nausea and vomiting

Take a lower dose with a low-protein snack.

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Study Notes

  • Dopamine agonists may cause sudden sleep events as an adverse effect.
  • A statement indicating the need for further teaching about carbidopa-levodopa is: "I should take the drug with food to increase absorption."
  • In response to a patient reporting no symptom improvement after 2 weeks on levodopa, the nurse should say, "It may take several months for a response to occur."
  • If a patient on levodopa develops dystonic movements and nausea, Bromocriptine (Parlodel) might replace the drug.
  • A patient on Selegiline HCI (Eldepryl) should avoid consuming foods that are high in tyramine.
  • When teaching about apomorphine, include that it does not have any opioid activity, a multidose injector pen is used, nausea may occur and can be treated with Tigan, and sleep attacks or daytime sleepiness may occur.
  • A statement by a student indicating a need for education about levodopa/carbidopa is: "Combination products cause fewer dyskinesias and decreased psychosis."
  • If a patient reports no change in symptoms after months on Sinemet, the provider should re-evaluate the diagnosis.
  • For a patient on Sinemet reporting "off" episodes occurring randomly, the nurse will suggest adding a COMT inhibitor like entacapone.
  • Non-drug recommendations for early-stage Parkinson's include recommending exercise, nutritional counseling, and support groups.
  • For a patient on rasagiline with high BP, the nurse should consider holding Ciprofloxacin.
  • If a patient on entacapone reports dizziness, you need to reduce the medication dosage.
  • When serving a meal to a patient on an MAO-B inhibitor, cheese should be removed.
  • The nurse should teach a patient starting carbidopa-levodopa to rise slowly from bed or a chair to avoid dizziness and falls.
  • A patient presenting with shuffling gait and resting tremors will likely be prescribed Carbidopa-levodopa (Sinemet).
  • Carbidopa is combined with levodopa to reduce peripheral side effects by inhibiting dopa decarboxylase in the periphery.
  • The side effect more likely with pramipexole than other dopamine agonists are sleep attacks.
  • A Parkinson patient on Sinemet developing tics indicates a need for a lower dose of Sinemet.
  • The levodopa side effect that supports a nursing diagnosis of "Risk for injury" is orthostatic hypotension.
  • For a patient on Sinemet reporting nausea and vomiting, the nurse should advise taking a lower dose with a low-protein snack.

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